domperidone has been researched along with Diarrhea in 8 studies
Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.
Diarrhea: An increased liquidity or decreased consistency of FECES, such as running stool. Fecal consistency is related to the ratio of water-holding capacity of insoluble solids to total water, rather than the amount of water present. Diarrhea is not hyperdefecation or increased fecal weight.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study sought to define the therapeutic efficacy of domperidone in infants and children with gastroesophageal reflux." | 9.07 | Efficacy of domperidone in infants and children with gastroesophageal reflux. ( Bines, JE; Kleinman, RE; Quinlan, JE; Treves, S; Winter, HS, 1992) |
| "There is increased awareness about risks and benefits of using domperidone to treat gastroparesis." | 7.83 | Domperidone to Treat Symptoms of Gastroparesis: Benefits and Side Effects from a Large Single-Center Cohort. ( Midani, D; Parkman, HP; Parupalli, R; Roberts, AC; Saadi, M; Schey, R, 2016) |
| "This study sought to define the therapeutic efficacy of domperidone in infants and children with gastroesophageal reflux." | 5.07 | Efficacy of domperidone in infants and children with gastroesophageal reflux. ( Bines, JE; Kleinman, RE; Quinlan, JE; Treves, S; Winter, HS, 1992) |
| " Ondansetron revealed the largest effect in comparison to placebo for cessation of vomiting (odds ratio = 0." | 5.05 | Antiemetics in Children With Acute Gastroenteritis: A Meta-analysis. ( Acosta-Reyes, J; Florez, ID; Niño-Serna, LF; Veroniki, AA, 2020) |
| "There is increased awareness about risks and benefits of using domperidone to treat gastroparesis." | 3.83 | Domperidone to Treat Symptoms of Gastroparesis: Benefits and Side Effects from a Large Single-Center Cohort. ( Midani, D; Parkman, HP; Parupalli, R; Roberts, AC; Saadi, M; Schey, R, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Niño-Serna, LF | 1 |
| Acosta-Reyes, J | 1 |
| Veroniki, AA | 1 |
| Florez, ID | 1 |
| Lewis, K | 1 |
| Alqahtani, Z | 1 |
| Mcintyre, L | 1 |
| Almenawer, S | 1 |
| Alshamsi, F | 1 |
| Rhodes, A | 1 |
| Evans, L | 1 |
| Angus, DC | 1 |
| Alhazzani, W | 1 |
| Schey, R | 1 |
| Saadi, M | 1 |
| Midani, D | 1 |
| Roberts, AC | 1 |
| Parupalli, R | 1 |
| Parkman, HP | 1 |
| Olver, IN | 1 |
| Laidlaw, CR | 1 |
| Matthews, JP | 1 |
| Bishop, JF | 1 |
| Hayes, AM | 1 |
| Wolf, M | 1 |
| Toner, GC | 1 |
| Bines, JE | 1 |
| Quinlan, JE | 1 |
| Treves, S | 1 |
| Kleinman, RE | 1 |
| Winter, HS | 1 |
| Layer, P | 1 |
| Goebell, H | 1 |
| Shafrir, Y | 1 |
| Levy, Y | 1 |
| Ben-Amitai, D | 1 |
| Nitzan, M | 1 |
| Steinherz, R | 1 |
| Friedman, G | 1 |
2 reviews available for domperidone and Diarrhea
| Article | Year |
|---|---|
Antiemetics in Children With Acute Gastroenteritis: A Meta-analysis.
Topics: Acute Disease; Antiemetics; Child; Child, Preschool; Dexamethasone; Diarrhea; Dimenhydrinate; Domper | 2020 |
The efficacy and safety of prokinetic agents in critically ill patients receiving enteral nutrition: a systematic review and meta-analysis of randomized trials.
Topics: Chi-Square Distribution; Critical Illness; Diarrhea; Domperidone; Dopamine Antagonists; Enteral Nutr | 2016 |
2 trials available for domperidone and Diarrhea
| Article | Year |
|---|---|
A randomised double blind crossover study of domperidone and prochlorperazine suppositories for controlling emesis in outpatients receiving chemotherapy.
Topics: Adult; Aged; Antineoplastic Agents; Diarrhea; Domperidone; Double-Blind Method; Female; Humans; Male | 1994 |
Efficacy of domperidone in infants and children with gastroesophageal reflux.
Topics: Child; Child, Preschool; Diarrhea; Domperidone; Double-Blind Method; Female; Gastric Emptying; Gastr | 1992 |
4 other studies available for domperidone and Diarrhea
| Article | Year |
|---|---|
Domperidone to Treat Symptoms of Gastroparesis: Benefits and Side Effects from a Large Single-Center Cohort.
Topics: Adult; Cohort Studies; Diabetes Complications; Diabetes Mellitus; Diarrhea; Domperidone; Dopamine An | 2016 |
[Therapy of motility disorders of the stomach and small intestine].
Topics: Cisapride; Constipation; Diarrhea; Domperidone; Dumping Syndrome; Gastric Emptying; Gastrointestinal | 1991 |
Oculogyric crisis due to domperidone therapy.
Topics: Basal Ganglia Diseases; Diarrhea; Domperidone; Humans; Infant; Male | 1985 |
New drugs in gastroenterology.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Antidiarrheals; Colit | 1985 |