domperidone has been researched along with Diabetes Mellitus, Adult-Onset in 5 studies
Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Domperidone has difficulty passing the blood-brain barrier, thus rarely causes tardive dyskinesia." | 7.91 | Severe tardive dyskinesia induced by domperidone in presenile and non-dementia type 2 diabetes man with alcohol misuse showing albuminocytological dissociation and white matter hyperintensity. ( Kanzaki, A; Nakamura, T; Otsuka, A; Tada, H, 2019) |
| "The purpose is to evaluate the effectiveness of itopride (IP) and domperidone (DP) in the treatment of patients with gastroesophageal reflux disease (GERD), in combination with diabetes mellitus (DM) type 1 and 2." | 5.17 | [Comparative data of prokinetics in treatment of gastroesophageal reflux disease in patients with diabetes]. ( Fedorchenko, IuL, 2013) |
| "Domperidone has difficulty passing the blood-brain barrier, thus rarely causes tardive dyskinesia." | 3.91 | Severe tardive dyskinesia induced by domperidone in presenile and non-dementia type 2 diabetes man with alcohol misuse showing albuminocytological dissociation and white matter hyperintensity. ( Kanzaki, A; Nakamura, T; Otsuka, A; Tada, H, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kanzaki, A | 1 |
| Tada, H | 1 |
| Otsuka, A | 1 |
| Nakamura, T | 1 |
| Janssen, P | 1 |
| Harris, MS | 1 |
| Jones, M | 1 |
| Masaoka, T | 1 |
| Farré, R | 1 |
| Törnblom, H | 1 |
| Van Oudenhove, L | 1 |
| Simrén, M | 1 |
| Tack, J | 1 |
| Fedorchenko, IuL | 1 |
| Segula, D | 1 |
| Mwandiambira, V | 1 |
| Howson, W | 1 |
| Allain, TJ | 1 |
| Wang, L | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Pilot, Randomized, Double-blind, Placebo-controlled Trial of Promethazine for Treatment of Diabetic Gastroparesis.[NCT02130622] | Phase 2 | 3 participants (Actual) | Interventional | 2014-07-31 | Terminated (stopped due to Lack of recruitment) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for domperidone and Diabetes Mellitus, Adult-Onset
| Article | Year |
|---|---|
The relation between symptom improvement and gastric emptying in the treatment of diabetic and idiopathic gastroparesis.
Topics: Cisapride; Diabetes Mellitus, Type 2; Domperidone; Erythromycin; Gastric Emptying; Gastrointestinal | 2013 |
2 trials available for domperidone and Diabetes Mellitus, Adult-Onset
| Article | Year |
|---|---|
[Comparative data of prokinetics in treatment of gastroesophageal reflux disease in patients with diabetes].
Topics: Adult; Benzamides; Benzyl Compounds; Diabetes Complications; Diabetes Mellitus, Type 1; Diabetes Mel | 2013 |
Clinical observation on acupuncture treatment in 35 cases of diabetic gastroparesis.
Topics: Acupuncture Therapy; Adult; Aged; Combined Modality Therapy; Diabetes Mellitus, Type 2; Domperidone; | 2004 |
2 other studies available for domperidone and Diabetes Mellitus, Adult-Onset
| Article | Year |
|---|---|
Severe tardive dyskinesia induced by domperidone in presenile and non-dementia type 2 diabetes man with alcohol misuse showing albuminocytological dissociation and white matter hyperintensity.
Topics: Alcoholism; Blood-Brain Barrier; Diabetes Mellitus, Type 2; Diagnosis, Differential; Domperidone; Do | 2019 |
Case report--the 46 year old man with a 5 month history of vomiting.
Topics: Antiemetics; Diabetes Mellitus, Type 2; Diagnosis, Differential; Domperidone; Gastroparesis; Humans; | 2011 |