domperidone has been researched along with Depressive Disorder in 3 studies
Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.
Depressive Disorder: An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood disturbance is prominent and relatively persistent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate whether the inhibitory control exerted by endogenous dopamine on thyroid-stimulating hormone (TSH) secretion is altered in patients with major depressive disorder, 11 depressed patients and 9 normal controls were tested with the dopaminergic receptor antagonist domperidone (10 or 20 mg i." | 3.67 | Dopaminergic control of TSH secretion in endogenous depression. ( Bianconi, L; Chiodera, P; Dassò, L; De Ferri, A; De Risio, C; Gnudi, A; Govi, AM; Marchesi, C; Minelli, R; Piagneri, B, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Johnson, TW | 1 |
| Polger, S | 1 |
| Emerich, DF | 1 |
| Freeman, TB | 1 |
| Cahill, DW | 1 |
| Sanberg, PR | 1 |
| Marchesi, C | 2 |
| Gnudi, A | 2 |
| Chiodera, P | 2 |
| De Risio, C | 2 |
| Fava, A | 1 |
| Dasso, L | 2 |
| De Ferri, A | 2 |
| Guerra, M | 1 |
| Coiro, V | 1 |
| Govi, AM | 1 |
| Piagneri, B | 1 |
| Minelli, R | 1 |
| Bianconi, L | 1 |
3 other studies available for domperidone and Depressive Disorder
| Article | Year |
|---|---|
Neuroleptic dysphoria: in search of an animal model.
Topics: Brain; Depressive Disorder; Domperidone; Haloperidol; Humans; Psychotic Disorders | 1993 |
Involvement of a dopaminergic mechanism in the response of growth hormone to thyrotropin releasing hormone in patients with major depression.
Topics: Adult; Aged; Aged, 80 and over; Depressive Disorder; Domperidone; Female; Growth Hormone; Humans; Ma | 1987 |
Dopaminergic control of TSH secretion in endogenous depression.
Topics: Adult; Aged; Aged, 80 and over; Brain; Depressive Disorder; Domperidone; Female; Humans; Male; Middl | 1988 |