domperidone has been researched along with Depressive Disorder, Major in 2 studies
Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.
Depressive Disorder, Major: Disorder in which five (or more) of the following symptoms have been present during the same 2-week period and represent a change from previous functioning; at least one of the symptoms is either (1) depressed mood or (2) loss of interest or pleasure. Symptoms include: depressed mood most of the day, nearly every daily; markedly diminished interest or pleasure in activities most of the day, nearly every day; significant weight loss when not dieting or weight gain; Insomnia or hypersomnia nearly every day; psychomotor agitation or retardation nearly every day; fatigue or loss of energy nearly every day; feelings of worthlessness or excessive or inappropriate guilt; diminished ability to think or concentrate, or indecisiveness, nearly every day; or recurrent thoughts of death, recurrent suicidal ideation without a specific plan, or a suicide attempt. (DSM-5)
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this report, we describe a case of domperidone withdrawal in a woman with a history of major depressive disorder and obsessive-compulsive disorder (OCD), who experienced a recurrence of these disorders after stopping domperidone." | 4.12 | Domperidone Withdrawal in a Nursing Female with Pre-existing Psychiatric Illness: A Case Report. ( Doobay, M; Sharma, S; Sharma, V, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sharma, V | 1 |
| Sharma, S | 1 |
| Doobay, M | 1 |
| Chang, CC | 1 |
| Shiah, IS | 1 |
| Chang, HA | 1 |
| Mao, WC | 1 |
2 other studies available for domperidone and Depressive Disorder, Major
| Article | Year |
|---|---|
Domperidone Withdrawal in a Nursing Female with Pre-existing Psychiatric Illness: A Case Report.
Topics: Anxiety Disorders; Comorbidity; Depressive Disorder, Major; Domperidone; Female; Humans; Obsessive-C | 2022 |
Does domperidone potentiate mirtazapine-associated restless legs syndrome?
Topics: Adult; Antidepressive Agents, Tricyclic; Depressive Disorder, Major; Domperidone; Dopamine Antagonis | 2006 |