domperidone has been researched along with Dementia in 1 studies
Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.
Dementia: An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Domperidone is a dopamine D₂ receptor antagonist that does not usually cross the blood-brain barrier." | 5.37 | Domperidone-induced tardive dyskinesia and withdrawal psychosis in an elderly woman with dementia. ( Bocti, C; Hottin, P; Landry, J; Roy-Desruisseaux, J; Tessier, D; Trudel, JF, 2011) |
| "Domperidone is a dopamine D₂ receptor antagonist that does not usually cross the blood-brain barrier." | 1.37 | Domperidone-induced tardive dyskinesia and withdrawal psychosis in an elderly woman with dementia. ( Bocti, C; Hottin, P; Landry, J; Roy-Desruisseaux, J; Tessier, D; Trudel, JF, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Roy-Desruisseaux, J | 1 |
| Landry, J | 1 |
| Bocti, C | 1 |
| Tessier, D | 1 |
| Hottin, P | 1 |
| Trudel, JF | 1 |
1 other study available for domperidone and Dementia
| Article | Year |
|---|---|
Domperidone-induced tardive dyskinesia and withdrawal psychosis in an elderly woman with dementia.
Topics: Aged; Blood-Brain Barrier; Dementia; Domperidone; Dopamine Antagonists; Dopamine D2 Receptor Antagon | 2011 |