domperidone has been researched along with Complications of Diabetes Mellitus in 20 studies
Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To describe the health-related quality of life (HRQOL) of patients with insulin-treated diabetes and symptoms of diabetic gastroparesis and to assess the impact of domperidone on HRQOL in these patients." | 9.08 | Effect of domperidone on the health-related quality of life of patients with symptoms of diabetic gastroparesis. ( Farup, CE; Helbers, L; Leidy, NK; Murray, M; Quigley, EM; Williams, GR, 1998) |
| "Despite being widely used in more than 20 countries for the treatment of diabetic gastroparesis for several decades, domperidone is approved only on an investigational basis in the United States." | 8.84 | A systematic review of the efficacy of domperidone for the treatment of diabetic gastroparesis. ( Pasricha, PJ; Singh, A; Sugumar, A, 2008) |
| "Domperidone improves symptoms of gastroparesis, reducing overall gastroparesis symptom severity and decreasing early satiety, postprandial fullness, and nausea." | 7.88 | Therapeutic response to domperidone in gastroparesis: A prospective study using the GCSI-daily diary. ( Heckert, J; Parkman, HP, 2018) |
| "There is increased awareness about risks and benefits of using domperidone to treat gastroparesis." | 7.83 | Domperidone to Treat Symptoms of Gastroparesis: Benefits and Side Effects from a Large Single-Center Cohort. ( Midani, D; Parkman, HP; Parupalli, R; Roberts, AC; Saadi, M; Schey, R, 2016) |
| "The purpose is to evaluate the effectiveness of itopride (IP) and domperidone (DP) in the treatment of patients with gastroesophageal reflux disease (GERD), in combination with diabetes mellitus (DM) type 1 and 2." | 5.17 | [Comparative data of prokinetics in treatment of gastroesophageal reflux disease in patients with diabetes]. ( Fedorchenko, IuL, 2013) |
| "To describe the health-related quality of life (HRQOL) of patients with insulin-treated diabetes and symptoms of diabetic gastroparesis and to assess the impact of domperidone on HRQOL in these patients." | 5.08 | Effect of domperidone on the health-related quality of life of patients with symptoms of diabetic gastroparesis. ( Farup, CE; Helbers, L; Leidy, NK; Murray, M; Quigley, EM; Williams, GR, 1998) |
| "Despite being widely used in more than 20 countries for the treatment of diabetic gastroparesis for several decades, domperidone is approved only on an investigational basis in the United States." | 4.84 | A systematic review of the efficacy of domperidone for the treatment of diabetic gastroparesis. ( Pasricha, PJ; Singh, A; Sugumar, A, 2008) |
| "Domperidone improves symptoms of gastroparesis, reducing overall gastroparesis symptom severity and decreasing early satiety, postprandial fullness, and nausea." | 3.88 | Therapeutic response to domperidone in gastroparesis: A prospective study using the GCSI-daily diary. ( Heckert, J; Parkman, HP, 2018) |
| "There is increased awareness about risks and benefits of using domperidone to treat gastroparesis." | 3.83 | Domperidone to Treat Symptoms of Gastroparesis: Benefits and Side Effects from a Large Single-Center Cohort. ( Midani, D; Parkman, HP; Parupalli, R; Roberts, AC; Saadi, M; Schey, R, 2016) |
| "Domperidone is a selective antagonist at peripheral dopamine D2 receptors, with gastroprokinetic and antiemetic properties." | 2.40 | Domperidone. A review of its use in diabetic gastropathy. ( Prakash, A; Wagstaff, AJ, 1998) |
| "Domperidone, which has also been shown to stimulate gastric motility and to possess antiemetic properties, improves symptoms in patients suffering from diabetic gastroparesis." | 2.38 | Use of metoclopramide, domperidone, and cisapride in the management of diabetic gastroparesis. ( Brown, CK; Khanderia, U, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (10.00) | 18.7374 |
| 1990's | 8 (40.00) | 18.2507 |
| 2000's | 4 (20.00) | 29.6817 |
| 2010's | 6 (30.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Asha, MZ | 1 |
| Khalil, SFH | 1 |
| Heckert, J | 1 |
| Parkman, HP | 2 |
| Kim, KH | 1 |
| Lee, MS | 1 |
| Choi, TY | 1 |
| Kim, TH | 1 |
| Fedorchenko, IuL | 1 |
| Schey, R | 1 |
| Saadi, M | 1 |
| Midani, D | 1 |
| Roberts, AC | 1 |
| Parupalli, R | 1 |
| Sugumar, A | 1 |
| Singh, A | 1 |
| Pasricha, PJ | 1 |
| Stiefelhagen, P | 1 |
| Kong, MF | 1 |
| Horowitz, M | 1 |
| Jiang, RQ | 1 |
| Zhang, DX | 1 |
| Bai, CY | 1 |
| Czambor-Ksiazek, E | 1 |
| Pokrzywnicki, W | 1 |
| Grzeszczak, W | 1 |
| Duda, G | 1 |
| Farup, CE | 1 |
| Leidy, NK | 1 |
| Murray, M | 1 |
| Williams, GR | 1 |
| Helbers, L | 1 |
| Quigley, EM | 1 |
| Prakash, A | 1 |
| Wagstaff, AJ | 1 |
| Dumitrascu, DL | 1 |
| Weinbeck, M | 1 |
| Drenth, JP | 1 |
| Engels, LG | 1 |
| Jian, R | 1 |
| Hongo, M | 1 |
| Toyota, T | 1 |
| Brown, CK | 1 |
| Khanderia, U | 1 |
| Hngo, M | 1 |
| Stern, WR | 1 |
| Ricci, DA | 1 |
| McCallum, RW | 1 |
9 reviews available for domperidone and Complications of Diabetes Mellitus
| Article | Year |
|---|---|
Pharmacological Approaches to Diabetic Gastroparesis: A systematic review of randomised clinical trials.
Topics: Antiemetics; Cisapride; Diabetes Complications; Domperidone; Gastric Emptying; Gastrointestinal Agen | 2019 |
Acupuncture for symptomatic gastroparesis.
Topics: Acupuncture Therapy; Benzamides; Cimetidine; Cisapride; Diabetes Complications; Domperidone; Gastroi | 2018 |
A systematic review of the efficacy of domperidone for the treatment of diabetic gastroparesis.
Topics: Clinical Trials as Topic; Diabetes Complications; Domperidone; Gastroparesis; Humans; Treatment Outc | 2008 |
[Disorders of gastric emptying in diabetes. II. Treatment].
Topics: Cisapride; Diabetes Complications; Domperidone; Dopamine Agents; Erythromycin; Gastric Emptying; Hum | 1997 |
Domperidone. A review of its use in diabetic gastropathy.
Topics: Animals; Diabetes Complications; Diabetes Mellitus, Experimental; Domperidone; Dopamine Antagonists; | 1998 |
Diabetic gastroparesis. A critical reappraisal of new treatment strategies.
Topics: Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cisapride; Diabetes | 1992 |
[Disorders of gastric emptying].
Topics: Cisapride; Diabetes Complications; Domperidone; Dyspepsia; Gastric Emptying; Gastroesophageal Reflux | 1992 |
Use of metoclopramide, domperidone, and cisapride in the management of diabetic gastroparesis.
Topics: Cisapride; Diabetes Complications; Domperidone; Gastric Emptying; Gastrointestinal Diseases; Humans; | 1990 |
Diagnosis and treatment of delayed gastric emptying.
Topics: Anemia, Pernicious; Anorexia Nervosa; Cisapride; Connective Tissue Diseases; Diabetes Complications; | 1988 |
5 trials available for domperidone and Complications of Diabetes Mellitus
| Article | Year |
|---|---|
[Comparative data of prokinetics in treatment of gastroesophageal reflux disease in patients with diabetes].
Topics: Adult; Benzamides; Benzyl Compounds; Diabetes Complications; Diabetes Mellitus, Type 1; Diabetes Mel | 2013 |
[Clinical study on Tangweikang in treating diabetic gastroparesis].
Topics: Aged; Antiemetics; Diabetes Complications; Domperidone; Drug Therapy, Combination; Drugs, Chinese He | 2007 |
Effect of domperidone on the health-related quality of life of patients with symptoms of diabetic gastroparesis.
Topics: Adult; Aged; Antiemetics; Diabetes Complications; Diabetes Mellitus; Domperidone; Double-Blind Metho | 1998 |
Domperidone versus metoclopramide in the treatment of diabetic gastroparesis.
Topics: Adult; Aged; Diabetes Complications; Domperidone; Double-Blind Method; Female; Gastric Emptying; Gas | 2000 |
Diabetic gastroparesis. A critical reappraisal of new treatment strategies.
Topics: Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cisapride; Diabetes | 1992 |
7 other studies available for domperidone and Complications of Diabetes Mellitus
| Article | Year |
|---|---|
Therapeutic response to domperidone in gastroparesis: A prospective study using the GCSI-daily diary.
Topics: Adult; Antiemetics; Diabetes Complications; Domperidone; Female; Gastric Emptying; Gastroparesis; Hu | 2018 |
Domperidone to Treat Symptoms of Gastroparesis: Benefits and Side Effects from a Large Single-Center Cohort.
Topics: Adult; Cohort Studies; Diabetes Complications; Diabetes Mellitus; Diarrhea; Domperidone; Dopamine An | 2016 |
[Prescriptions for gastroparesis].
Topics: Antiemetics; Diabetes Complications; Diagnosis, Differential; Domperidone; Gastroparesis; Humans; Ma | 2010 |
Diabetic gastroparesis.
Topics: Adult; Antiemetics; Diabetes Complications; Diet; Domperidone; Dopamine Agonists; Erythromycin; Fema | 2005 |
[Diabetic gastropathy].
Topics: Diabetes Complications; Domperidone; Gastric Emptying; Gastrointestinal Motility; Humans; Insulin; M | 1991 |
[Effect of acute and long-term administration of a stimulative agent on gastrointestinal motility in the therapy of patients with diabetic gastroparesis].
Topics: Diabetes Complications; Diabetes Mellitus; Domperidone; Female; Gastric Emptying; Humans; Male; Midd | 1990 |
Summary of the 34th meeting of the Food and Drug Administration Gastrointestinal Drugs Advisory Committee. March 15 and 16, 1989 (omeprazole and domperidone).
Topics: Animals; Diabetes Complications; Domperidone; Duodenal Ulcer; Gastroesophageal Reflux; Humans; Omepr | 1989 |