Page last updated: 2024-10-26

domperidone and Colonic Inertia

domperidone has been researched along with Colonic Inertia in 4 studies

Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.

Colonic Inertia: Symptom characterized by the passage of stool once a week or less.

Research Excerpts

ExcerptRelevanceReference
"There was no additional effect of domperidone as adjunct to PEG in the treatment of children with constipation."9.19Oral domperidone has no additional effect on chronic functional constipation in children: a randomized clinical trial. ( Askarian, M; Dehghani, SM; Kaffashan, HA, 2014)
"There was no additional effect of domperidone as adjunct to PEG in the treatment of children with constipation."5.19Oral domperidone has no additional effect on chronic functional constipation in children: a randomized clinical trial. ( Askarian, M; Dehghani, SM; Kaffashan, HA, 2014)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Gimeno-García, AZ1
González-Suárez, B1
Ganzo, ZA1
Fernández, OA1
Ramos, L1
Giordano, A1
Carretero, C1
Jiménez, A1
Nicolás, D1
Guerra, MH1
Quintero, E1
Dehghani, SM1
Askarian, M1
Kaffashan, HA1
Hanauer, SB1
Layer, P1
Goebell, H1

Trials

1 trial available for domperidone and Colonic Inertia

ArticleYear
Oral domperidone has no additional effect on chronic functional constipation in children: a randomized clinical trial.
    Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 2014, Volume: 33, Issue:2

    Topics: Administration, Oral; Child; Child, Preschool; Chronic Disease; Constipation; Domperidone; Dopamine

2014

Other Studies

3 other studies available for domperidone and Colonic Inertia

ArticleYear
Predictive factors for inadequate bowel cleansing in colon capsule endoscopy.
    Gastroenterologia y hepatologia, 2022, Volume: 45, Issue:8

    Topics: Aged; Bisacodyl; Capsule Endoscopy; Cathartics; Colon; Colonoscopy; Constipation; Diatrizoate Meglum

2022
Moving ahead or falling behind?
    Nature clinical practice. Gastroenterology & hepatology, 2007, Volume: 4, Issue:6

    Topics: Cisapride; Constipation; Domperidone; Gastrointestinal Agents; Gastrointestinal Diseases; Gastrointe

2007
[Therapy of motility disorders of the stomach and small intestine].
    Deutsche medizinische Wochenschrift (1946), 1991, Feb-22, Volume: 116, Issue:8

    Topics: Cisapride; Constipation; Diarrhea; Domperidone; Dumping Syndrome; Gastric Emptying; Gastrointestinal

1991