domperidone has been researched along with Colonic Diseases, Functional in 7 studies
Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.
Colonic Diseases, Functional: Chronic or recurrent colonic disorders without an identifiable structural or biochemical explanation. The widely recognized IRRITABLE BOWEL SYNDROME falls into this category.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Domperidone treatment did not differ significantly from placebo treatment in irritable bowel syndrome patients concurrently put on high fibre diet." | 2.65 | Domperidone treatment in the irritable bowel syndrome. ( Fielding, JF, 1982) |
| "Domperidone was taken at a dosage of 10 mg tablets 4-times daily." | 2.65 | Use of the peripheral dopamine antagonist, domperidone, in the management of gastro-intestinal symptoms in patients with irritable bowel syndrome. ( Milo, R, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fielding, JF | 1 |
| Cann, PA | 2 |
| Read, NW | 1 |
| Holdsworth, CD | 1 |
| Milo, R | 1 |
| Champion, MC | 1 |
| Fallingborg, J | 1 |
| Christensen, LA | 1 |
| Nielsen, ST | 1 |
| Thommesen, P | 1 |
| Jensen, PF | 1 |
| Lanfranchi, GA | 1 |
| Bazzocchi, G | 1 |
| Fois, F | 1 |
| Brignola, C | 1 |
| Campieri, M | 1 |
| Menni, B | 1 |
1 review available for domperidone and Colonic Diseases, Functional
| Article | Year |
|---|---|
Domperidone.
Topics: Colonic Diseases, Functional; Domperidone; Dyspepsia; Esophagitis, Peptic; Gastrointestinal Motility | 1988 |
4 trials available for domperidone and Colonic Diseases, Functional
| Article | Year |
|---|---|
Domperidone treatment in the irritable bowel syndrome.
Topics: Adolescent; Adult; Clinical Trials as Topic; Colonic Diseases, Functional; Dietary Fiber; Domperidon | 1982 |
Oral domperidone: double blind comparison with placebo in irritable bowel syndrome.
Topics: Administration, Oral; Adult; Clinical Trials as Topic; Colonic Diseases, Functional; Domperidone; Do | 1983 |
Use of the peripheral dopamine antagonist, domperidone, in the management of gastro-intestinal symptoms in patients with irritable bowel syndrome.
Topics: Abdomen; Adult; Aged; Benzimidazoles; Clinical Trials as Topic; Colonic Diseases, Functional; Defeca | 1980 |
[Domperidone in the treatment of irritable colon. A placebo-controlled double-blind study].
Topics: Adult; Clinical Trials as Topic; Colonic Diseases, Functional; Domperidone; Double-Blind Method; Fem | 1987 |
2 other studies available for domperidone and Colonic Diseases, Functional
| Article | Year |
|---|---|
An approach to the design of therapeutic trials in IBS.
Topics: Clinical Trials as Topic; Colonic Diseases, Functional; Domperidone; Dose-Response Relationship, Dru | 1987 |
Effect of domperidone and dopamine on colonic motor activity in patients with the irritable bowel syndrome.
Topics: Adult; Colon; Colonic Diseases, Functional; Domperidone; Dopamine; Female; Gastrointestinal Motility | 1985 |