domperidone has been researched along with Cardiovascular Diseases in 2 studies
Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.
Cardiovascular Diseases: Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.
| Excerpt | Relevance | Reference |
|---|---|---|
| "domperidone was administered to both 6-hydroxydopamine Parkinsonism models and regular Wistar rats." | 1.51 | Cardiovascular alterations in rats with Parkinsonism induced by 6-OHDA and treated with Domperidone. ( Britto, LRG; Faber, J; Ferraz, HB; Oliveira, LF; Rodrigues, LD; Scorza, CA; Scorza, FA; Shinoda, L, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shin, SM | 1 |
| Jeong, HE | 1 |
| Lee, H | 1 |
| Shin, JY | 1 |
| Rodrigues, LD | 1 |
| Oliveira, LF | 1 |
| Shinoda, L | 1 |
| Scorza, CA | 1 |
| Faber, J | 1 |
| Ferraz, HB | 1 |
| Britto, LRG | 1 |
| Scorza, FA | 1 |
2 other studies available for domperidone and Cardiovascular Diseases
| Article | Year |
|---|---|
Association between domperidone use and adverse cardiovascular events: A nested case-control and case-time-control study.
Topics: Cardiovascular Diseases; Case-Control Studies; Domperidone; Humans; Metoclopramide; Odds Ratio | 2020 |
Cardiovascular alterations in rats with Parkinsonism induced by 6-OHDA and treated with Domperidone.
Topics: Animals; Behavior, Animal; Cardiovascular Diseases; Disease Models, Animal; Domperidone; Dopamine An | 2019 |