domperidone has been researched along with Cardiomegaly in 1 studies
Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.
Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In ovariectomized female rats raised at sea level, domperidone, a peripheral D2-receptor antagonist, increased ventilation in normoxia (minute ventilation = +55%) and acute hypoxia (+32%)." | 3.71 | Dopaminergic metabolism in carotid bodies and high-altitude acclimatization in female rats. ( Favier, R; Joseph, V; Pequignot, J; Pequignot, JM; Soliz, J; Soria, R; Spielvogel, H, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Joseph, V | 1 |
| Soliz, J | 1 |
| Soria, R | 1 |
| Pequignot, J | 1 |
| Favier, R | 1 |
| Spielvogel, H | 1 |
| Pequignot, JM | 1 |
1 other study available for domperidone and Cardiomegaly
| Article | Year |
|---|---|
Dopaminergic metabolism in carotid bodies and high-altitude acclimatization in female rats.
Topics: Acclimatization; Altitude; Animals; Cardiomegaly; Carotid Body; Catecholamines; Domperidone; Dopamin | 2002 |