domperidone has been researched along with Carcinoma, Hepatocellular in 1 studies
Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.
Carcinoma, Hepatocellular: A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.
| Excerpt | Relevance | Reference |
|---|---|---|
| "PRL deficiency accelerated liver carcinogenesis in Prl(-/-) mice of both sexes." | 1.40 | Prolactin prevents hepatocellular carcinoma by restricting innate immune activation of c-Myc in mice. ( Fox, JG; Hartwell, HJ; Horseman, ND; Petrosky, KY; Rogers, AB, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hartwell, HJ | 1 |
| Petrosky, KY | 1 |
| Fox, JG | 1 |
| Horseman, ND | 1 |
| Rogers, AB | 1 |
1 other study available for domperidone and Carcinoma, Hepatocellular
| Article | Year |
|---|---|
Prolactin prevents hepatocellular carcinoma by restricting innate immune activation of c-Myc in mice.
Topics: Adult; Animals; Carcinogenesis; Carcinoma, Hepatocellular; Domperidone; Female; Humans; Immunity, In | 2014 |