domperidone has been researched along with Carcinogenesis in 1 studies
Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.
Carcinogenesis: The origin, production or development of cancer through genotypic and phenotypic changes which upset the normal balance between cell proliferation and cell death. Carcinogenesis generally requires a constellation of steps, which may occur quickly or over a period of many years.
| Excerpt | Relevance | Reference |
|---|---|---|
| "PRL deficiency accelerated liver carcinogenesis in Prl(-/-) mice of both sexes." | 1.40 | Prolactin prevents hepatocellular carcinoma by restricting innate immune activation of c-Myc in mice. ( Fox, JG; Hartwell, HJ; Horseman, ND; Petrosky, KY; Rogers, AB, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hartwell, HJ | 1 |
| Petrosky, KY | 1 |
| Fox, JG | 1 |
| Horseman, ND | 1 |
| Rogers, AB | 1 |
1 other study available for domperidone and Carcinogenesis
| Article | Year |
|---|---|
Prolactin prevents hepatocellular carcinoma by restricting innate immune activation of c-Myc in mice.
Topics: Adult; Animals; Carcinogenesis; Carcinoma, Hepatocellular; Domperidone; Female; Humans; Immunity, In | 2014 |