domperidone has been researched along with Cancer of Liver in 3 studies
Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Domperidone use was analyzed overall, and by number of prescriptions and cumulative dose." | 1.48 | Domperidone use and risk of primary liver cancer in the Clinical Practice Research Datalink. ( Bradley, MC; Graubard, BI; McGlynn, KA; Petrick, JL; Thistle, JE; Yang, B, 2018) |
| "PRL deficiency accelerated liver carcinogenesis in Prl(-/-) mice of both sexes." | 1.40 | Prolactin prevents hepatocellular carcinoma by restricting innate immune activation of c-Myc in mice. ( Fox, JG; Hartwell, HJ; Horseman, ND; Petrosky, KY; Rogers, AB, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Thistle, JE | 1 |
| Petrick, JL | 1 |
| Yang, B | 1 |
| Bradley, MC | 1 |
| Graubard, BI | 1 |
| McGlynn, KA | 1 |
| Uña, E | 1 |
| Alonso, P | 1 |
| Hartwell, HJ | 1 |
| Petrosky, KY | 1 |
| Fox, JG | 1 |
| Horseman, ND | 1 |
| Rogers, AB | 1 |
1 review available for domperidone and Cancer of Liver
| Article | Year |
|---|---|
High dose of prokinetics for refractory hiccups after chemotherapy or the return to a simple drug.
Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Domperidone; Dopamine Antagonists | 2013 |
2 other studies available for domperidone and Cancer of Liver
| Article | Year |
|---|---|
Domperidone use and risk of primary liver cancer in the Clinical Practice Research Datalink.
Topics: Adult; Biomedical Research; Case-Control Studies; Databases, Factual; Domperidone; Dopamine Antagoni | 2018 |
Prolactin prevents hepatocellular carcinoma by restricting innate immune activation of c-Myc in mice.
Topics: Adult; Animals; Carcinogenesis; Carcinoma, Hepatocellular; Domperidone; Female; Humans; Immunity, In | 2014 |