Page last updated: 2024-10-26

domperidone and Breast Cancer

domperidone has been researched along with Breast Cancer in 4 studies

Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.

Research Excerpts

ExcerptRelevanceReference
" CMF were included in a double-blind comparative study aimed at evaluating the efficacy of 3 different drugs (methylprednisolone (MP), metoclopramide (MTC), and domperidone (DMP) in preventing chemotherapy-induced nausea and vomiting."9.06Double-blind controlled trial of the antiemetic efficacy and toxicity of methylprednisolone (MP), metoclopramide (MTC) and domperidone (DMP) in breast cancer patients treated with i.v. CMF. ( Ballatori, E; Basurto, C; del Favero, A; Minotti, V; Roila, F; Tonato, M, 1987)
" CMF were included in a double-blind comparative study aimed at evaluating the efficacy of 3 different drugs (methylprednisolone (MP), metoclopramide (MTC), and domperidone (DMP) in preventing chemotherapy-induced nausea and vomiting."5.06Double-blind controlled trial of the antiemetic efficacy and toxicity of methylprednisolone (MP), metoclopramide (MTC) and domperidone (DMP) in breast cancer patients treated with i.v. CMF. ( Ballatori, E; Basurto, C; del Favero, A; Minotti, V; Roila, F; Tonato, M, 1987)
"Domperidone was given twice a day for one week."1.27[Effect of combined use of adrenocortical hormones and domperidone as anti-emetics during cisplatin therapy]. ( Hirose, Y; Matsushita, T; Mise, K; Nakanishi, M; Shirosaki, H; Tanaka, T; Yamaoto, T, 1985)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (25.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Stricker, HM1
Rommerswinkel, N1
Keil, S1
Gnoth, SA1
Niggemann, B1
Dittmar, T1
Ye, Q1
Kantonen, S1
Gomez-Cambronero, J1
Roila, F1
Tonato, M1
Basurto, C1
Minotti, V1
Ballatori, E1
del Favero, A1
Tanaka, T1
Nakanishi, M1
Hirose, Y1
Mise, K1
Matsushita, T1
Yamaoto, T1
Shirosaki, H1

Trials

1 trial available for domperidone and Breast Cancer

ArticleYear
Double-blind controlled trial of the antiemetic efficacy and toxicity of methylprednisolone (MP), metoclopramide (MTC) and domperidone (DMP) in breast cancer patients treated with i.v. CMF.
    European journal of cancer & clinical oncology, 1987, Volume: 23, Issue:6

    Topics: Age Factors; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as To

1987

Other Studies

3 other studies available for domperidone and Breast Cancer

ArticleYear
The phospholipase D inhibitor FIPI potently blocks EGF-induced calcium signaling in human breast cancer cells.
    Cell communication and signaling : CCS, 2021, 04-08, Volume: 19, Issue:1

    Topics: Breast Neoplasms; Calcium; Calcium Signaling; Cell Line, Tumor; Cell Movement; Domperidone; Enzyme I

2021
Serum deprivation confers the MDA-MB-231 breast cancer line with an EGFR/JAK3/PLD2 system that maximizes cancer cell invasion.
    Journal of molecular biology, 2013, Feb-22, Volume: 425, Issue:4

    Topics: Apigenin; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Culture Media, Serum

2013
[Effect of combined use of adrenocortical hormones and domperidone as anti-emetics during cisplatin therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:5

    Topics: Adult; Aged; Breast Neoplasms; Cisplatin; Domperidone; Drug Therapy, Combination; Esophageal Neoplas

1985