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domperidone and Bradycardia

domperidone has been researched along with Bradycardia in 4 studies

Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.

Bradycardia: Cardiac arrhythmias that are characterized by excessively slow HEART RATE, usually below 50 beats per minute in human adults. They can be classified broadly into SINOATRIAL NODE dysfunction and ATRIOVENTRICULAR BLOCK.

Research Excerpts

ExcerptRelevanceReference
"A central dopaminergic origin has been demonstrated for the bromocriptine-induced tachycardia in conscious, normotensive rats."7.71Central bromocriptine-induced tachycardia is reversed to bradycardia in conscious, deoxycorticosterone acetate-salt hypertensive rats. ( Lahlou, S, 2001)
"A central dopaminergic origin has been demonstrated for the bromocriptine-induced tachycardia in conscious, normotensive rats."3.71Central bromocriptine-induced tachycardia is reversed to bradycardia in conscious, deoxycorticosterone acetate-salt hypertensive rats. ( Lahlou, S, 2001)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's2 (50.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ritchie, HE1
Huss, IB1
Webster, WS1
Vermeylen, D1
Franco, P1
Hennequin, Y1
Pardou, A1
Brugmans, M1
Simon, P1
Hassid, S1
Lahlou, S2

Trials

1 trial available for domperidone and Bradycardia

ArticleYear
Laryngeal oedema in neonatal apnoea and bradycardia syndrome (a pilot study).
    Early human development, 2005, Volume: 81, Issue:4

    Topics: Administration, Inhalation; Administration, Oral; Adrenal Cortex Hormones; Bradycardia; Caffeine; De

2005

Other Studies

3 other studies available for domperidone and Bradycardia

ArticleYear
The effect of anti-emetic drugs on rat embryonic heart activity.
    Reproductive toxicology (Elmsford, N.Y.), 2019, Volume: 87

    Topics: Animals; Antiemetics; Bradycardia; Domperidone; Droperidol; Embryo, Mammalian; Granisetron; Heart; H

2019
Involvement of spinal dopamine receptors in mediation of the hypotensive and bradycardic effects of systemic quinpirole in anaesthetised rats.
    European journal of pharmacology, 1998, Jul-24, Volume: 353, Issue:2-3

    Topics: Animals; Bradycardia; Domperidone; Dopamine Agonists; Dose-Response Relationship, Drug; Hypotension;

1998
Central bromocriptine-induced tachycardia is reversed to bradycardia in conscious, deoxycorticosterone acetate-salt hypertensive rats.
    Pharmacology & toxicology, 2001, Volume: 88, Issue:5

    Topics: Animals; Aorta, Abdominal; Blood Pressure; Bradycardia; Bromocriptine; Desoxycorticosterone; Domperi

2001