Page last updated: 2024-10-26

domperidone and Bilateral Headache

domperidone has been researched along with Bilateral Headache in 8 studies

Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.

Research Excerpts

ExcerptRelevanceReference
"There is increased awareness about risks and benefits of using domperidone to treat gastroparesis."7.83Domperidone to Treat Symptoms of Gastroparesis: Benefits and Side Effects from a Large Single-Center Cohort. ( Midani, D; Parkman, HP; Parupalli, R; Roberts, AC; Saadi, M; Schey, R, 2016)
"To determine the safety of domperidone in the treatment of nausea associated with dihydroergotamine (DHE) infusion and headache."7.83Safety of domperidone in treating nausea associated with dihydroergotamine infusion and headache. ( Goadsby, PJ; Ito, H; Robbins, NM; Scheinman, MM, 2016)
"Etiology identification of the stroke included cardiogenic pathology and coagulopathy, but acitretin treatment was considered the likeliest explanation."7.71Acitretin-associated thrombotic stroke. ( Davani, S; Kantelip, JP; Muret, P; Royer, B; Ziegler, F, 2002)
"There is increased awareness about risks and benefits of using domperidone to treat gastroparesis."3.83Domperidone to Treat Symptoms of Gastroparesis: Benefits and Side Effects from a Large Single-Center Cohort. ( Midani, D; Parkman, HP; Parupalli, R; Roberts, AC; Saadi, M; Schey, R, 2016)
"To determine the safety of domperidone in the treatment of nausea associated with dihydroergotamine (DHE) infusion and headache."3.83Safety of domperidone in treating nausea associated with dihydroergotamine infusion and headache. ( Goadsby, PJ; Ito, H; Robbins, NM; Scheinman, MM, 2016)
"Domperidone is a dopamine antagonist that has recently been released in Canada."3.76Domperidone, a new dopamine antagonist. ( Champion, MC; Hartnett, M; Yen, M, 1986)
"Etiology identification of the stroke included cardiogenic pathology and coagulopathy, but acitretin treatment was considered the likeliest explanation."3.71Acitretin-associated thrombotic stroke. ( Davani, S; Kantelip, JP; Muret, P; Royer, B; Ziegler, F, 2002)
"Cephalalgias are divided into four syndromes and the most severe of these, migraine, presents several therapeutic applications."2.38[Therapy of headache]. ( Cavanna, M, 1989)
"Patients with migraine show a hypersensitivity to dopamine or its agonists."1.27Pharmacological exploration of dopamine hypersensitivity in migraine patients. ( Bès, A; Bessoles, G; Dupui, P; Géraud, G; Güell, A, 1986)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19903 (37.50)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's4 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Braillon, A1
Robbins, NM2
Goadsby, PJ2
Schey, R1
Saadi, M1
Midani, D1
Roberts, AC1
Parupalli, R1
Parkman, HP1
Ito, H1
Scheinman, MM1
Royer, B1
Ziegler, F1
Muret, P1
Davani, S1
Kantelip, JP1
Cavanna, M1
Champion, MC1
Hartnett, M1
Yen, M1
Bès, A1
Dupui, P1
Güell, A1
Bessoles, G1
Géraud, G1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Oral Domperidone for Relief of Gastrointestinal Disorders in Patients Who Failed Standard Therapy[NCT00761254]42 participants (Actual)Interventional2008-08-31Terminated (stopped due to PI withdrew due to increased responsibilities in clinical department.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for domperidone and Bilateral Headache

ArticleYear
[Therapy of headache].
    La Clinica terapeutica, 1989, Apr-30, Volume: 129, Issue:2

    Topics: Cluster Headache; Dextropropoxyphene; Dihydroergotamine; Domperidone; Ergotamine; Headache; Humans;

1989
Domperidone, a new dopamine antagonist.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 1986, Sep-01, Volume: 135, Issue:5

    Topics: Administration, Oral; Adult; Child; Clinical Trials as Topic; Domperidone; Dopamine Antagonists; Dys

1986

Trials

1 trial available for domperidone and Bilateral Headache

ArticleYear
Domperidone, a new dopamine antagonist.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 1986, Sep-01, Volume: 135, Issue:5

    Topics: Administration, Oral; Adult; Child; Clinical Trials as Topic; Domperidone; Dopamine Antagonists; Dys

1986

Other Studies

6 other studies available for domperidone and Bilateral Headache

ArticleYear
Letter re: Safety of domperidone in treating nausea associated with dihydroergotamine infusion and headache.
    Neurology, 2017, 05-30, Volume: 88, Issue:22

    Topics: Dihydroergotamine; Domperidone; Headache; Humans; Nausea

2017
Author response: Safety of domperidone in treating nausea associated with dihydroergotamine infusion and headache.
    Neurology, 2017, 05-30, Volume: 88, Issue:22

    Topics: Dihydroergotamine; Domperidone; Headache; Humans; Nausea

2017
Domperidone to Treat Symptoms of Gastroparesis: Benefits and Side Effects from a Large Single-Center Cohort.
    Digestive diseases and sciences, 2016, Volume: 61, Issue:12

    Topics: Adult; Cohort Studies; Diabetes Complications; Diabetes Mellitus; Diarrhea; Domperidone; Dopamine An

2016
Safety of domperidone in treating nausea associated with dihydroergotamine infusion and headache.
    Neurology, 2016, Dec-13, Volume: 87, Issue:24

    Topics: Adolescent; Adult; Aged; Antiemetics; Dihydroergotamine; Domperidone; Female; Headache; Humans; Male

2016
Acitretin-associated thrombotic stroke.
    The Annals of pharmacotherapy, 2002, Volume: 36, Issue:12

    Topics: Acitretin; Analgesics; Anticoagulants; Antiemetics; Dextropropoxyphene; Domperidone; Female; Headach

2002
Pharmacological exploration of dopamine hypersensitivity in migraine patients.
    International journal of clinical pharmacology research, 1986, Volume: 6, Issue:3

    Topics: Cerebrovascular Circulation; Domperidone; Dopamine; Headache; Humans; Hypotension; Migraine Disorder

1986