domperidone has been researched along with Autosomal Dominant Juvenile Parkinson Disease in 2 studies
Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.
| Excerpt | Relevance | Reference |
|---|---|---|
| "domperidone was administered to both 6-hydroxydopamine Parkinsonism models and regular Wistar rats." | 1.51 | Cardiovascular alterations in rats with Parkinsonism induced by 6-OHDA and treated with Domperidone. ( Britto, LRG; Faber, J; Ferraz, HB; Oliveira, LF; Rodrigues, LD; Scorza, CA; Scorza, FA; Shinoda, L, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rodrigues, LD | 1 |
| Oliveira, LF | 1 |
| Shinoda, L | 1 |
| Scorza, CA | 1 |
| Faber, J | 1 |
| Ferraz, HB | 1 |
| Britto, LRG | 1 |
| Scorza, FA | 1 |
| Zhao, T | 1 |
| Zondervan-van der Linde, H | 1 |
| Severijnen, LA | 1 |
| Oostra, BA | 1 |
| Willemsen, R | 1 |
| Bonifati, V | 1 |
2 other studies available for domperidone and Autosomal Dominant Juvenile Parkinson Disease
| Article | Year |
|---|---|
Cardiovascular alterations in rats with Parkinsonism induced by 6-OHDA and treated with Domperidone.
Topics: Animals; Behavior, Animal; Cardiovascular Diseases; Disease Models, Animal; Domperidone; Dopamine An | 2019 |
Dopaminergic neuronal loss and dopamine-dependent locomotor defects in Fbxo7-deficient zebrafish.
Topics: Animals; Apomorphine; Body Patterning; Brain; Disease Models, Animal; Domperidone; Dopamine; Dopamin | 2012 |