domperidone has been researched along with Appetite Disorders in 2 studies
Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of the DA receptor antagonists metoclopramide and pimozide on food and water intake in male Sprague Dawley rats were compared to those of domperidone, which does not cross the blood-brain barrier, in an attempt to determine whether any extracerebral DA receptors participate in neuroleptic induced anorexia." | 3.66 | Neuroleptic-like anorexia produced by an extra-cerebral DA antagonist. ( Kinchington, PC; Smith, GC; Willis, GL, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Willis, GL | 2 |
| Smith, GC | 2 |
| Kinchington, PC | 1 |
| Sleeman, M | 1 |
| Brodie, G | 1 |
2 other studies available for domperidone and Appetite Disorders
| Article | Year |
|---|---|
Neuroleptic-like anorexia produced by an extra-cerebral DA antagonist.
Topics: Animals; Anorexia; Antipsychotic Agents; Brain; Domperidone; Drinking Behavior; Feeding and Eating D | 1983 |
Observations on dopamine receptor antagonists and gastric ulceration associated with experimental anorexia cachexia.
Topics: Animals; Anorexia; Cachexia; Carcinoma 256, Walker; Domperidone; Dopamine; Dopamine Antagonists; Dri | 1988 |