Page last updated: 2024-10-26

domperidone and Anorexia Nervosa

domperidone has been researched along with Anorexia Nervosa in 5 studies

Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.

Anorexia Nervosa: An eating disorder that is characterized by the lack or loss of APPETITE, known as ANOREXIA. Other features include excess fear of becoming OVERWEIGHT; BODY IMAGE disturbance; significant WEIGHT LOSS; refusal to maintain minimal normal weight; and AMENORRHEA. This disorder occurs most frequently in adolescent females. (APA, Thesaurus of Psychological Index Terms, 1994)

Research Excerpts

ExcerptRelevanceReference
"A woman with anorexia nervosa who displayed severe bloating after eating was treated with domperidone, a novel compound with prokinetic properties."7.66Delayed gastric emptying and improvement with domperidone in a patient with anorexia nervosa. ( Feiglin, DH; Freedman, ML; Garfinkel, PE; Jeejeebhoy, KN; Russell, DM; Swinson, RP, 1983)
"symptoms of disordered upper gastrointestinal motor activity may be mistaken as indicating primary anorexia nervosa; clinical evaluation of patients with presumed primary anorexia nervosa should rule out the possibility that disordered oesophageal motor activity underlies the symptoms; delayed gastric emptying is a frequent feature in primary anorexia nervosa and might be returned to normal with domperidone."5.06Oesophageal and gastric motility disorders in patients categorised as having primary anorexia nervosa. ( Bergmann, H; Höbart, J; Kiss, A; Schneider, C; Stacher, G; Wiesnagrotzki, S, 1986)
" The circadian rhythm of beta-endorphin (beta-EP) and beta-lipotropin (beta-LPH), and their responses to the administration of corticotropin releasing hormone (CRH, 1 micrograms/kg body weight, i."3.68Peripheral opioid secretory pattern in anorexia nervosa. ( Brambilla, F; Catalano, M; Facchinetti, F; Ferrari, E; Genazzani, AR; Petraglia, F, 1991)
"A woman with anorexia nervosa who displayed severe bloating after eating was treated with domperidone, a novel compound with prokinetic properties."3.66Delayed gastric emptying and improvement with domperidone in a patient with anorexia nervosa. ( Feiglin, DH; Freedman, ML; Garfinkel, PE; Jeejeebhoy, KN; Russell, DM; Swinson, RP, 1983)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19904 (80.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Russell, DM1
Freedman, ML1
Feiglin, DH1
Jeejeebhoy, KN1
Swinson, RP1
Garfinkel, PE1
Brambilla, F1
Ferrari, E1
Petraglia, F1
Facchinetti, F1
Catalano, M1
Genazzani, AR1
Devesa, J1
Pérez-Fernández, R1
Bokser, L1
Gaudiero, GJ1
Lima, L1
Casanueva, FF1
Ricci, DA1
McCallum, RW1
Stacher, G1
Kiss, A1
Wiesnagrotzki, S1
Bergmann, H1
Höbart, J1
Schneider, C1

Reviews

1 review available for domperidone and Anorexia Nervosa

ArticleYear
Diagnosis and treatment of delayed gastric emptying.
    Advances in internal medicine, 1988, Volume: 33

    Topics: Anemia, Pernicious; Anorexia Nervosa; Cisapride; Connective Tissue Diseases; Diabetes Complications;

1988

Trials

1 trial available for domperidone and Anorexia Nervosa

ArticleYear
Oesophageal and gastric motility disorders in patients categorised as having primary anorexia nervosa.
    Gut, 1986, Volume: 27, Issue:10

    Topics: Adolescent; Adult; Anorexia Nervosa; Diagnosis, Differential; Domperidone; Esophageal Diseases; Fema

1986

Other Studies

3 other studies available for domperidone and Anorexia Nervosa

ArticleYear
Delayed gastric emptying and improvement with domperidone in a patient with anorexia nervosa.
    The American journal of psychiatry, 1983, Volume: 140, Issue:9

    Topics: Adult; Anorexia Nervosa; Domperidone; Female; Gastric Emptying; Humans; Hyperphagia; Satiation

1983
Peripheral opioid secretory pattern in anorexia nervosa.
    Psychiatry research, 1991, Volume: 39, Issue:2

    Topics: 5-Hydroxytryptophan; Adolescent; Adult; Anorexia Nervosa; beta-Endorphin; beta-Lipotropin; Body Weig

1991
Adrenal androgen secretion and dopaminergic activity in anorexia nervosa.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1988, Volume: 20, Issue:1

    Topics: Adolescent; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Androgens; Androstenedione; Anorexia

1988