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domperidone and Anochlesia

domperidone has been researched along with Anochlesia in 7 studies

Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.

Research Excerpts

ExcerptRelevanceReference
"The intensity of DOM-induced catalepsy was significantly potentiated by the coadministration of CsA."1.32Potentiation of domperidone-induced catalepsy by a P-glycoprotein inhibitor, cyclosporin A. ( Dan, Y; Iga, T; Murakami, H; Nogawa, K; Ohtani, H; Sato, H; Sawada, Y; Tsujikawa, K; Yamada, Y, 2003)
"The emetic and catalepsy-inducing actions of buflomedil were studied in dog and mice."1.27[Emetic and catalepsy-inducing actions of buflomedil]. ( Hashimoto, T; Koda, H; Kuriyama, K, 1988)
"The chronic administration of haloperidol (HAL), domperidone (DOM), or sulpiride (SUL) increased the density of striatal dopamine (DA) receptors in intact but not in hypophysectomized (Hypox) male rats."1.27Modulatory role for prolactin in the elevation of striatal dopamine receptor density induced by chronic treatment with dopamine receptor antagonists. ( Hruska, RE, 1986)
"Prior to the induction of catalepsy and after recovery from it, mice display the entire range of typical apomorphine-induced behavior including sniffing, climbing, gnawing, and licking."1.27Simultaneous catalepsy and apomorphine-induced stereotypic behavior in mice. ( Randall, PK; Yurek, DM, 1985)
"Domperidone induced a weak catalepsy in decompressed rats, but failed to induce any catalepsy in control rats."1.26Changes in blood-brain barrier permeability to drugs in decompressed rats. ( Kaakkola, S; Laitinen, LA; Lehtosalo, J, 1982)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19905 (71.43)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Monković, I1
Willner, D1
Adam, MA1
Brown, M1
Crenshaw, RR1
Fuller, CE1
Juby, PF1
Luke, GM1
Matiskella, JA1
Montzka, TA1
Koener, B1
Goursaud, S1
Van De Stadt, M1
Calas, AG1
Jeanjean, AP1
Maloteaux, JM1
Hermans, E1
Tsujikawa, K1
Dan, Y1
Nogawa, K1
Sato, H1
Yamada, Y1
Murakami, H1
Ohtani, H1
Sawada, Y1
Iga, T1
Kaakkola, S1
Lehtosalo, J1
Laitinen, LA1
Koda, H1
Hashimoto, T1
Kuriyama, K1
Hruska, RE1
Yurek, DM1
Randall, PK1

Other Studies

7 other studies available for domperidone and Anochlesia

ArticleYear
Substituted benzamides. 1. Potential nondopaminergic antagonists of chemotherapy-induced nausea and emesis.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:8

    Topics: Animals; Antiemetics; Benzamides; Catalepsy; Chemical Phenomena; Chemistry; Cisplatin; Dogs; Dopamin

1988
Pharmacological blockade of dopamine D2 receptors by aripiprazole is not associated with striatal sensitization.
    Naunyn-Schmiedeberg's archives of pharmacology, 2011, Volume: 383, Issue:1

    Topics: Animals; Apomorphine; Aripiprazole; Buffers; Catalepsy; Cell Membrane; Cerebral Cortex; Corpus Stria

2011
Potentiation of domperidone-induced catalepsy by a P-glycoprotein inhibitor, cyclosporin A.
    Biopharmaceutics & drug disposition, 2003, Volume: 24, Issue:3

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Catalepsy; Cyclosporine; Domperido

2003
Changes in blood-brain barrier permeability to drugs in decompressed rats.
    Undersea biomedical research, 1982, Volume: 9, Issue:3

    Topics: Animals; Atropine; Atropine Derivatives; Blood-Brain Barrier; Catalepsy; Decompression Sickness; Dom

1982
[Emetic and catalepsy-inducing actions of buflomedil].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1988, Volume: 92, Issue:6

    Topics: Administration, Oral; Animals; Bromocriptine; Catalepsy; Dogs; Domperidone; Dose-Response Relationsh

1988
Modulatory role for prolactin in the elevation of striatal dopamine receptor density induced by chronic treatment with dopamine receptor antagonists.
    Brain research bulletin, 1986, Volume: 16, Issue:3

    Topics: Animals; Behavior, Animal; Catalepsy; Corpus Striatum; Domperidone; Haloperidol; Male; Prolactin; Ra

1986
Simultaneous catalepsy and apomorphine-induced stereotypic behavior in mice.
    Life sciences, 1985, Nov-04, Volume: 37, Issue:18

    Topics: Animals; Apomorphine; Catalepsy; Chlorpromazine; Domperidone; Drug Interactions; Haloperidol; Inject

1985