domperidone has been researched along with Anhedonia in 1 studies
Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.
Anhedonia: Inability to experience pleasure due to impairment or dysfunction of normal psychological and neurobiological mechanisms. It is a symptom of many PSYCHOTIC DISORDERS (e.g., DEPRESSIVE DISORDER, MAJOR; and SCHIZOPHRENIA).
| Excerpt | Relevance | Reference |
|---|---|---|
| " Imipramine was administered for the next 5 weeks, and it reversed anhedonia in majority of animals (imipramine-reactive); however, in some animals, it did not (imipramine-non-reactive)." | 3.88 | Regulation of somatostatin receptor 2 in the context of antidepressant treatment response in chronic mild stress in rat. ( Antkiewicz-Michaluk, L; Dziedzicka-Wasylewska, M; Faron-Górecka, A; Gruca, P; Kolasa, M; Kuśmider, M; Pabian, P; Papp, M; Romańska, I; Solich, J; Szlachta, M; Żurawek, D, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Faron-Górecka, A | 1 |
| Kuśmider, M | 1 |
| Solich, J | 1 |
| Kolasa, M | 1 |
| Pabian, P | 1 |
| Gruca, P | 1 |
| Romańska, I | 1 |
| Żurawek, D | 1 |
| Szlachta, M | 1 |
| Papp, M | 1 |
| Antkiewicz-Michaluk, L | 1 |
| Dziedzicka-Wasylewska, M | 1 |
1 other study available for domperidone and Anhedonia
| Article | Year |
|---|---|
Regulation of somatostatin receptor 2 in the context of antidepressant treatment response in chronic mild stress in rat.
Topics: Anhedonia; Animals; Antidepressive Agents; Autoradiography; Brain; Depression; Disease Models, Anima | 2018 |