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domperidone and Anesthesia

domperidone has been researched along with Anesthesia in 19 studies

Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.

Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.

Research Excerpts

ExcerptRelevanceReference
" We wanted to study the effects of the new antiemetic Domperidone on vomiting after either anesthesia."9.05[Domperidone after ether anaesthesia. Prevention of postoperative hyperemesis (author's transl)]. ( Alon, E; Axhausen, C; Bernoulli, L; Caluori, R; Hossli, G, 1982)
" We wanted to study the effects of the new antiemetic Domperidone on vomiting after either anesthesia."5.05[Domperidone after ether anaesthesia. Prevention of postoperative hyperemesis (author's transl)]. ( Alon, E; Axhausen, C; Bernoulli, L; Caluori, R; Hossli, G, 1982)
"The administration of alfentanil by continuous infusion as supplementation to nitrous oxide for shortlasting anesthesias has been studied in 51 patients."3.66Continuous infusion of alfentanil. ( Booij, LH; Pelgrom, R; Steegers, PA, 1982)
" SCH23390 (3-30 nmol), a selective D-1 DA receptor antagonist, caused a progressive parallel shift to the right in the dose-response curve for DA-induced pancreatic secretion without changes in the maximal response."1.29D-1 dopamine receptors mediate dopamine-induced pancreatic exocrine secretion in anesthetized dogs. ( Chiba, S; Horiuchi, A; Iwatsuki, K; Ren, LM, 1995)
"Metoclopramide pretreatment in urethane-anesthetized rats prevented the decreases in MAP and heart rate induced by LY171555, whereas pretreatment with d(CH2)5Tyr(Me)AVP delayed the recovery phase of the depressor response."1.27Mechanism of the depressor action of LY171555, a selective dopamine D2 receptor agonist, in the anesthetized rat. ( Chen, YF; Lindheimer, MD; Nagahama, S; Oparil, S, 1986)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-199013 (68.42)18.7374
1990's5 (26.32)18.2507
2000's1 (5.26)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Monteiro, TC1
Obeso, A1
Gonzalez, C1
Monteiro, EC1
Palazzo, MG1
Strunin, L1
Steegers, PA1
Booij, LH1
Pelgrom, R1
Minobe, T1
Sekine, H1
Torii, T1
Fujiya, T1
Ohtomo, Y1
Alon, E1
Caluori, R1
Bernoulli, L1
Axhausen, C1
Hossli, G1
Tatsumi, K1
Pickett, CK1
Weil, JV1
Iwatsuki, K1
Horiuchi, A1
Ren, LM1
Chiba, S1
Clark, KL1
Robertson, MJ1
Drew, GM1
Nishiyama, S1
Yoshikawa, M1
Yamaguchi, I1
Lahlou, S1
Demenge, P1
Kopia, GA1
Valocik, RE1
Montastruc, P1
Damase-Michel, C1
Montastruc, JL1
Sowinski, BA1
Lokhandwala, MF1
Foucart, S1
Lacaille-Belanger, P1
Kimura, T1
Nadeau, R1
de Champlain, J1
Ensinger, H1
Majewski, H1
Hedler, L1
Starke, K1
Böhmer, G1
Löffelholz, K1
Schmid, K1
Raach, M1
Gouzoulis, E1
Nagahama, S1
Chen, YF1
Lindheimer, MD1
Oparil, S1
Delpierre, S1
Peyrot, J1
Guillot, C1
Grimaud, C1
Salvati, P1
Bianchi, G1

Reviews

1 review available for domperidone and Anesthesia

ArticleYear
Anaesthesia and emesis. II: Prevention and management.
    Canadian Anaesthetists' Society journal, 1984, Volume: 31, Issue:4

    Topics: Anesthesia; Antiemetics; Butyrophenones; Domperidone; Histamine H1 Antagonists; Humans; Metocloprami

1984

Trials

2 trials available for domperidone and Anesthesia

ArticleYear
[The effect of domperidone in the prevention of nausea and vomiting during post-operative recovery period from anesthesia--a double blind study (author's transl)].
    Masui. The Japanese journal of anesthesiology, 1981, Volume: 30, Issue:12

    Topics: Adult; Anesthesia; Clinical Trials as Topic; Domperidone; Double-Blind Method; Female; Humans; Male;

1981
[Domperidone after ether anaesthesia. Prevention of postoperative hyperemesis (author's transl)].
    Der Anaesthesist, 1982, Volume: 31, Issue:4

    Topics: Adult; Aged; Anesthesia; Domperidone; Ether; Ethyl Ethers; Female; Humans; Male; Middle Aged; Postop

1982

Other Studies

16 other studies available for domperidone and Anesthesia

ArticleYear
Does ageing modify ventilatory responses to dopamine in anaesthetised rats breathing spontaneously?
    Advances in experimental medicine and biology, 2009, Volume: 648

    Topics: Aging; Anesthesia; Animals; Domperidone; Dopamine; Dopamine Antagonists; Dose-Response Relationship,

2009
Continuous infusion of alfentanil.
    Acta anaesthesiologica Belgica, 1982, Volume: 33, Issue:2

    Topics: Adult; Alfentanil; Anesthesia; Blood Pressure; Domperidone; Droperidol; Female; Fentanyl; Heart Rate

1982
Decreased carotid body hypoxic sensitivity in chronic hypoxia: role of dopamine.
    Respiration physiology, 1995, Volume: 101, Issue:1

    Topics: Anesthesia; Animals; Carotid Body; Carotid Sinus; Cats; Chronic Disease; Domperidone; Dopamine; Dopa

1995
D-1 dopamine receptors mediate dopamine-induced pancreatic exocrine secretion in anesthetized dogs.
    Hypertension research : official journal of the Japanese Society of Hypertension, 1995, Volume: 18 Suppl 1

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Anesthesia; Animals; Benzazepines; Dogs;

1995
Do renal tubular dopamine receptors mediate dopamine-induced diuresis in the anesthetized cat?
    Journal of cardiovascular pharmacology, 1991, Volume: 17, Issue:2

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Anesthesia; Animals; Benzazepines; Cats;

1991
A novel orally active dopamine (DA) prodrug TA-870. IV. Renal vasodilatory and negative chronotropic effects in anesthetized dogs: influence of DA1 and DA2 dopamine receptor selective antagonists.
    Journal of cardiovascular pharmacology, 1991, Volume: 17, Issue:4

    Topics: Anesthesia; Animals; Benzazepines; Blood Pressure; Depression, Chemical; Dogs; Domperidone; Dopamine

1991
Contribution of spinal dopamine receptors to the hypotensive action of bromocriptine in rats.
    Journal of cardiovascular pharmacology, 1991, Volume: 18, Issue:3

    Topics: Anesthesia; Animals; Antihypertensive Agents; Blood Pressure; Bromocriptine; Domperidone; Dose-Respo

1991
Demonstration of specific dopamine-1 receptor-mediated coronary vasodilation in the anesthetized dog.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 248, Issue:1

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Anesthesia; Angina Pectoris; Animals; Be

1989
Apomorphine potentiates vagal bradycardia.
    European journal of pharmacology, 1989, Aug-03, Volume: 166, Issue:3

    Topics: Anesthesia; Animals; Apomorphine; Benzazepines; Blood Pressure; Dogs; Domperidone; Dopamine Antagoni

1989
Identification of dopamine receptor subtypes in the hypotensive action of SK&F 85174 in anesthetized rats.
    Journal of autonomic pharmacology, 1987, Volume: 7, Issue:2

    Topics: Anesthesia; Animals; Antipsychotic Agents; Benzazepines; Blood Pressure; Domperidone; Ergolines; Hea

1987
Modulation of adrenal catecholamine release by DA2 dopamine receptors in the anaesthetized dog.
    Clinical and experimental pharmacology & physiology, 1988, Volume: 15, Issue:8

    Topics: Adrenal Glands; Adrenal Medulla; Anesthesia; Animals; Blood Pressure; Catecholamines; Dimethyl Sulfo

1988
Neuronal and postjunctional components in the blood pressure effects of dopamine and bromocriptine in rabbits.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 234, Issue:3

    Topics: Anesthesia; Animals; Benzazepines; Blood Pressure; Bromocriptine; Clonidine; Decerebrate State; Desi

1985
Dopaminergic control of respiration as shown by effects of 4-aminopyridine.
    European journal of pharmacology, 1986, Jan-29, Volume: 120, Issue:3

    Topics: 4-Aminopyridine; Aminopyridines; Anesthesia; Animals; Atropine; Domperidone; Dopamine; Haloperidol;

1986
Mechanism of the depressor action of LY171555, a selective dopamine D2 receptor agonist, in the anesthetized rat.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 239, Issue:2

    Topics: Anesthesia; Animals; Arginine Vasopressin; Blood Pressure; Domperidone; Drug Interactions; Epinephri

1986
Ventilatory effects of domperidone, a new dopamine antagonist, in anaesthetized rabbits.
    Archives internationales de pharmacodynamie et de therapie, 1985, Volume: 275, Issue:1

    Topics: Anesthesia; Animals; Blood Gas Analysis; Carbon Dioxide; Domperidone; Dopamine Antagonists; Heart Ra

1985
Involvement of peripheral dopamine receptors in the antihypertensive effect of a new ergoline derivative (355/1057).
    Archives internationales de pharmacodynamie et de therapie, 1985, Volume: 274, Issue:2

    Topics: Anesthesia; Animals; Antihypertensive Agents; Blood Pressure; Cats; Dogs; Domperidone; Ergolines; Fe

1985