Page last updated: 2024-10-26

domperidone and Alloxan Diabetes

domperidone has been researched along with Alloxan Diabetes in 4 studies

Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.

Research Excerpts

ExcerptRelevanceReference
"Domperidone is a selective antagonist at peripheral dopamine D2 receptors, with gastroprokinetic and antiemetic properties."2.40Domperidone. A review of its use in diabetic gastropathy. ( Prakash, A; Wagstaff, AJ, 1998)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's3 (75.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Xie, W1
Xing, D1
Zhao, Y1
Su, H1
Meng, Z1
Chen, Y1
Du, L1
Luippold, G2
Beilharz, M2
Wehrmann, M1
Unger, L1
Gross, G1
Mühlbauer, B2
Prakash, A1
Wagstaff, AJ1

Reviews

1 review available for domperidone and Alloxan Diabetes

ArticleYear
Domperidone. A review of its use in diabetic gastropathy.
    Drugs, 1998, Volume: 56, Issue:3

    Topics: Animals; Diabetes Complications; Diabetes Mellitus, Experimental; Domperidone; Dopamine Antagonists;

1998

Other Studies

3 other studies available for domperidone and Alloxan Diabetes

ArticleYear
A new tactic to treat postprandial hyperlipidemia in diabetic rats with gastroparesis by improving gastrointestinal transit.
    European journal of pharmacology, 2005, Mar-07, Volume: 510, Issue:1-2

    Topics: Administration, Oral; Animals; Diabetes Mellitus, Experimental; Domperidone; Dopamine Antagonists; D

2005
Effect of dopamine D3 receptor blockade on renal function and glomerular size in diabetic rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 2005, Volume: 371, Issue:5

    Topics: Animals; Cattle; Diabetes Mellitus, Experimental; Domperidone; Dopamine Antagonists; Glomerular Filt

2005
Reduction of glomerular hyperfiltration by dopamine D(2)-like receptor blockade in experimental diabetes mellitus.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2001, Volume: 16, Issue:7

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Domperidone; Dopamine Antagonists; Dopamine

2001