domperidone has been researched along with Alcoholism in 3 studies
Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.
Alcoholism: A primary, chronic disease with genetic, psychosocial, and environmental factors influencing its development and manifestations. The disease is often progressive and fatal. It is characterized by impaired control over drinking, preoccupation with the drug alcohol, use of alcohol despite adverse consequences, and distortions in thinking, most notably denial. Each of these symptoms may be continuous or periodic. (Morse & Flavin for the Joint Commission of the National Council on Alcoholism and Drug Dependence and the American Society of Addiction Medicine to Study the Definition and Criteria for the Diagnosis of Alcoholism: in JAMA 1992;268:1012-4)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Domperidone has difficulty passing the blood-brain barrier, thus rarely causes tardive dyskinesia." | 7.91 | Severe tardive dyskinesia induced by domperidone in presenile and non-dementia type 2 diabetes man with alcohol misuse showing albuminocytological dissociation and white matter hyperintensity. ( Kanzaki, A; Nakamura, T; Otsuka, A; Tada, H, 2019) |
| "Domperidone has difficulty passing the blood-brain barrier, thus rarely causes tardive dyskinesia." | 3.91 | Severe tardive dyskinesia induced by domperidone in presenile and non-dementia type 2 diabetes man with alcohol misuse showing albuminocytological dissociation and white matter hyperintensity. ( Kanzaki, A; Nakamura, T; Otsuka, A; Tada, H, 2019) |
| " In the first case, the drugs venlafaxine, amiodarone and domperidone may have contributed to QT interval prolongation in a patient with hypokalemia and hypomagnesaemia." | 3.76 | Multifactorial QT interval prolongation. ( Baranchuk, A; Digby, G; Machaalany, J; Malik, P; Methot, M; Redfearn, D; Simpson, CS, 2010) |
| "The phenomenon of sudden cardiac death is usually related to the worsening of existing heart conditions leading to ventricular arrhythmia (VA)." | 1.42 | A case of sudden cardiac death following Domperidone self-medication. ( De Leo, D; Fais, P; Gottardo, R; Laposata, C; Lockwood, R; Vermiglio, E, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kanzaki, A | 1 |
| Tada, H | 1 |
| Otsuka, A | 1 |
| Nakamura, T | 1 |
| Fais, P | 1 |
| Vermiglio, E | 1 |
| Laposata, C | 1 |
| Lockwood, R | 1 |
| Gottardo, R | 1 |
| De Leo, D | 1 |
| Digby, G | 1 |
| Machaalany, J | 1 |
| Malik, P | 1 |
| Methot, M | 1 |
| Simpson, CS | 1 |
| Redfearn, D | 1 |
| Baranchuk, A | 1 |
3 other studies available for domperidone and Alcoholism
| Article | Year |
|---|---|
Severe tardive dyskinesia induced by domperidone in presenile and non-dementia type 2 diabetes man with alcohol misuse showing albuminocytological dissociation and white matter hyperintensity.
Topics: Alcoholism; Blood-Brain Barrier; Diabetes Mellitus, Type 2; Diagnosis, Differential; Domperidone; Do | 2019 |
A case of sudden cardiac death following Domperidone self-medication.
Topics: Alcoholism; Arrhythmias, Cardiac; Death, Sudden, Cardiac; Domperidone; Female; Gastrointestinal Agen | 2015 |
Multifactorial QT interval prolongation.
Topics: Alcoholism; Amiodarone; Antipsychotic Agents; Arrhythmias, Cardiac; Biomarkers; Citalopram; Cyclohex | 2010 |