domperidone has been researched along with Aging in 11 studies
Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Out-of-hospital sudden cardiac death was assessed by linkage with Hospital Episode Statistics and death certificates." | 1.42 | Risk of Out-of-Hospital Sudden Cardiac Death in Users of Domperidone, Proton Pump Inhibitors, or Metoclopramide: A Population-Based Nested Case-Control Study. ( Arana, A; Fife, D; Johannes, CB; McQuay, LJ; Rothman, KJ; Varas-Lorenzo, C, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (36.36) | 18.7374 |
| 1990's | 3 (27.27) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 2 (18.18) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arana, A | 1 |
| Johannes, CB | 1 |
| McQuay, LJ | 1 |
| Varas-Lorenzo, C | 1 |
| Fife, D | 1 |
| Rothman, KJ | 1 |
| Monteiro, TC | 1 |
| Obeso, A | 1 |
| Gonzalez, C | 1 |
| Monteiro, EC | 1 |
| Morcom, AM | 1 |
| Bullmore, ET | 1 |
| Huppert, FA | 1 |
| Lennox, B | 1 |
| Praseedom, A | 1 |
| Linnington, H | 1 |
| Fletcher, PC | 1 |
| Ibayashi, H | 2 |
| Tomares, SM | 1 |
| Bamford, OS | 1 |
| Sterni, LM | 1 |
| Fitzgerald, RS | 1 |
| Carroll, JL | 1 |
| Prasad, C | 1 |
| Ikegami, H | 1 |
| Shimizu, I | 1 |
| Onaivi, ES | 1 |
| Bairam, A | 1 |
| Kinkead, R | 1 |
| Marchal, F | 1 |
| Arey, BJ | 1 |
| Freeman, ME | 1 |
| Gelbard, HA | 1 |
| Teicher, MH | 1 |
| Faedda, G | 1 |
| Baldessarini, RJ | 1 |
| Giusti, M | 1 |
| Lomeo, A | 1 |
| Marini, G | 1 |
| Attanasio, R | 1 |
| Barreca, A | 1 |
| Camogliano, L | 1 |
| Peluffo, F | 1 |
| Giordano, G | 1 |
| Muta, K | 1 |
| Maki, T | 1 |
| Kato, K | 1 |
2 trials available for domperidone and Aging
| Article | Year |
|---|---|
Memory encoding and dopamine in the aging brain: a psychopharmacological neuroimaging study.
Topics: Adolescent; Adult; Aged; Aging; Analysis of Variance; Brain; Brain Mapping; Cross-Over Studies; Domp | 2010 |
Role of aging on growth hormone and prolactin release after growth hormone-releasing hormone and domperidone in man.
Topics: Adult; Aged; Aged, 80 and over; Aging; Domperidone; Growth Hormone; Growth Hormone-Releasing Hormone | 1987 |
9 other studies available for domperidone and Aging
| Article | Year |
|---|---|
Risk of Out-of-Hospital Sudden Cardiac Death in Users of Domperidone, Proton Pump Inhibitors, or Metoclopramide: A Population-Based Nested Case-Control Study.
Topics: Aging; Antiemetics; Case-Control Studies; Death, Sudden, Cardiac; Domperidone; Dose-Response Relatio | 2015 |
Does ageing modify ventilatory responses to dopamine in anaesthetised rats breathing spontaneously?
Topics: Aging; Anesthesia; Animals; Domperidone; Dopamine; Dopamine Antagonists; Dose-Response Relationship, | 2009 |
[Aging and hormones].
Topics: Adrenocorticotropic Hormone; Adult; Aged; Aging; Domperidone; Estradiol; Female; Follicle Stimulatin | 1983 |
The role of endogenous dopamine as an inhibitory neuromodulator in neonatal and adult carotid bodies.
Topics: Aging; Animals; Animals, Newborn; Carotid Body; Cats; Domperidone; Dopamine; Female; Hypoxia; Male; | 1994 |
Chronic nicotine intake decelerates aging of nigrostriatal dopaminergic neurons.
Topics: Aging; Animals; Apomorphine; Benzazepines; Binding Sites; Body Weight; Cellular Senescence; Corpus S | 1994 |
Age-dependent effect of domperidone on dopamine release by the hypoxic carotid body in the rabbit.
Topics: Aging; Animals; Carotid Body; Domperidone; Dopamine; Dopamine Antagonists; In Vitro Techniques; Oxyg | 2001 |
Ontogeny of the endogenous stimulatory rhythm regulating prolactin secretion in immature female rats.
Topics: Aging; Animals; Circadian Rhythm; Domperidone; Female; Prolactin; Rats | 1991 |
Postnatal development of dopamine D1 and D2 receptor sites in rat striatum.
Topics: Aging; Animals; Benzazepines; Corpus Striatum; Domperidone; Female; Rats; Rats, Inbred Strains; Rece | 1989 |
[Aging in the dopaminergic regulation of the pituitary hormone secretion in men (II): Changes in the pituitary response to domperidone].
Topics: Adult; Aged; Aged, 80 and over; Aging; Domperidone; Dopamine; Humans; Hypothalamo-Hypophyseal System | 1986 |