domperidone has been researched along with Adrenal Cancer in 2 studies
Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The gastroprokinetic agent metoclopramide is known to stimulate catecholamine secretion from pheochromocytomas." | 7.75 | Metoclopramide stimulates catecholamine- and granin-derived peptide secretion from pheochromocytoma cells through activation of serotonin type 4 (5-HT4) receptors. ( Anouar, Y; Bastard, C; Bertherat, J; Cartier, D; Compagnon, P; Guillemot, J; Kuhn, JM; Lefebvre, H; Lihrmann, I; Pichon, P; Plouin, PF; Thouennon, E; Thuillez, C; Yon, L, 2009) |
| "Administration of two dopamine antagonists, domperidone and metoclopramide, gave a marked rise in blood pressure with an increase in plasma catecholamines in two patients with pheochromocytoma." | 7.67 | Increase in blood pressure in pheochromocytoma induced by domperidone and metoclopramide. ( Arai, M; Ichikawa, S; Murata, K; Ono, Z, 1985) |
| "The gastroprokinetic agent metoclopramide is known to stimulate catecholamine secretion from pheochromocytomas." | 3.75 | Metoclopramide stimulates catecholamine- and granin-derived peptide secretion from pheochromocytoma cells through activation of serotonin type 4 (5-HT4) receptors. ( Anouar, Y; Bastard, C; Bertherat, J; Cartier, D; Compagnon, P; Guillemot, J; Kuhn, JM; Lefebvre, H; Lihrmann, I; Pichon, P; Plouin, PF; Thouennon, E; Thuillez, C; Yon, L, 2009) |
| "Administration of two dopamine antagonists, domperidone and metoclopramide, gave a marked rise in blood pressure with an increase in plasma catecholamines in two patients with pheochromocytoma." | 3.67 | Increase in blood pressure in pheochromocytoma induced by domperidone and metoclopramide. ( Arai, M; Ichikawa, S; Murata, K; Ono, Z, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Guillemot, J | 1 |
| Compagnon, P | 1 |
| Cartier, D | 1 |
| Thouennon, E | 1 |
| Bastard, C | 1 |
| Lihrmann, I | 1 |
| Pichon, P | 1 |
| Thuillez, C | 1 |
| Plouin, PF | 1 |
| Bertherat, J | 1 |
| Anouar, Y | 1 |
| Kuhn, JM | 1 |
| Yon, L | 1 |
| Lefebvre, H | 1 |
| Ichikawa, S | 1 |
| Ono, Z | 1 |
| Arai, M | 1 |
| Murata, K | 1 |
2 other studies available for domperidone and Adrenal Cancer
| Article | Year |
|---|---|
Metoclopramide stimulates catecholamine- and granin-derived peptide secretion from pheochromocytoma cells through activation of serotonin type 4 (5-HT4) receptors.
Topics: Adrenal Gland Neoplasms; Adrenal Medulla; Catecholamines; Chromogranins; Cisapride; Contraindication | 2009 |
Increase in blood pressure in pheochromocytoma induced by domperidone and metoclopramide.
Topics: Adrenal Gland Neoplasms; Adult; Blood Pressure; Domperidone; Epinephrine; Female; Humans; Hypertensi | 1985 |