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domperidone and Adenoma, Prolactin-Secreting, Pituitary

domperidone has been researched along with Adenoma, Prolactin-Secreting, Pituitary in 7 studies

Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.

Research Excerpts

ExcerptRelevanceReference
"Eighty-four patients (10 male, 74 female) whose investigation of hyperprolactinaemia included a domperidone test and high resolution pituitary MRI."7.69An audit of the diagnostic usefulness of PRL and TSH responses to domperidone and high resolution magnetic resonance imaging of the pituitary in the evaluation of hyperprolactinaemia. ( Bevan, JS; Robb, OJ; Sawers, HA; Shaw, J; Strachan, FM; Walmsley, D, 1997)
"These results suggestthat in PES with prolactinoma the inhibiting dopaminergic tone is increased on the thyrotropic cells and reduced on the lactotropic cells in PES with elevated PRL and that some patients with PES might bear a microprolactinoma in the bottom of the sella which remained undetected by the CT scan."5.29TSH and prolactin responses to thyrotropin releasing hormone (TRH) and domperidone in patients with empty sella syndrome. ( Attali, JR; Combes, ME; Perret, G; Valensi, P, 1996)
"Eighty-four patients (10 male, 74 female) whose investigation of hyperprolactinaemia included a domperidone test and high resolution pituitary MRI."3.69An audit of the diagnostic usefulness of PRL and TSH responses to domperidone and high resolution magnetic resonance imaging of the pituitary in the evaluation of hyperprolactinaemia. ( Bevan, JS; Robb, OJ; Sawers, HA; Shaw, J; Strachan, FM; Walmsley, D, 1997)
"These results suggestthat in PES with prolactinoma the inhibiting dopaminergic tone is increased on the thyrotropic cells and reduced on the lactotropic cells in PES with elevated PRL and that some patients with PES might bear a microprolactinoma in the bottom of the sella which remained undetected by the CT scan."1.29TSH and prolactin responses to thyrotropin releasing hormone (TRH) and domperidone in patients with empty sella syndrome. ( Attali, JR; Combes, ME; Perret, G; Valensi, P, 1996)
"Microprolactinoma is a particular pathological situation characterized by the presence of increased hypothalamic dopaminergic tone reactive to tumoral hyperprolactinemia."1.28Thyrotropin alpha- and beta-subunit responses to thyrotropin-releasing hormone and domperidone in normal subjects and in patients with microprolactinomas. ( Beck-Peccoz, P; Conti, A; Faglia, G; Medri, G; Persani, L, 1991)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (85.71)18.2507
2000's1 (14.29)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pinto, LP1
Hanna, FW1
Evans, LM1
Davies, JS1
John, R1
Scanlon, MF2
Valensi, P1
Combes, ME1
Perret, G1
Attali, JR1
Sawers, HA1
Robb, OJ1
Walmsley, D1
Strachan, FM1
Shaw, J1
Bevan, JS2
Lu, F1
Wu, H1
Zhang, K1
Li, D1
Webster, J1
Page, MD1
Richards, SH1
Douglas-Jones, AG1
Persani, L1
Beck-Peccoz, P1
Medri, G1
Conti, A1
Faglia, G1
Ciccarelli, E1
Ghigo, E1
Miola, C1
Gandini, G1
Muller, EE1
Camanni, F1

Other Studies

7 other studies available for domperidone and Adenoma, Prolactin-Secreting, Pituitary

ArticleYear
The TSH response to domperidone reflects the biological activity of prolactin in macroprolactinaemia and hyperprolactinaemia.
    Clinical endocrinology, 2003, Volume: 59, Issue:5

    Topics: Adult; Domperidone; Dopamine Antagonists; Female; Humans; Hyperprolactinemia; Middle Aged; Pituitary

2003
TSH and prolactin responses to thyrotropin releasing hormone (TRH) and domperidone in patients with empty sella syndrome.
    Journal of endocrinological investigation, 1996, Volume: 19, Issue:5

    Topics: Adult; Domperidone; Empty Sella Syndrome; Female; Humans; Hyperprolactinemia; Male; Middle Aged; Pit

1996
An audit of the diagnostic usefulness of PRL and TSH responses to domperidone and high resolution magnetic resonance imaging of the pituitary in the evaluation of hyperprolactinaemia.
    Clinical endocrinology, 1997, Volume: 46, Issue:3

    Topics: Adolescent; Adult; Domperidone; Dopamine Antagonists; Female; Humans; Hyperprolactinemia; Magnetic R

1997
[Domperidone and hyperprolactinemia].
    Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University, 1998, Volume: 23, Issue:1

    Topics: Adult; Domperidone; Female; Gastrointestinal Agents; Humans; Hyperprolactinemia; Middle Aged; Pituit

1998
Low recurrence rate after partial hypophysectomy for prolactinoma: the predictive value of dynamic prolactin function tests.
    Clinical endocrinology, 1992, Volume: 36, Issue:1

    Topics: Adult; Domperidone; Female; Follow-Up Studies; Humans; Hypophysectomy; Male; Middle Aged; Neoplasm R

1992
Thyrotropin alpha- and beta-subunit responses to thyrotropin-releasing hormone and domperidone in normal subjects and in patients with microprolactinomas.
    Neuroendocrinology, 1991, Volume: 53, Issue:4

    Topics: Adult; Domperidone; Dopamine; Female; Follicle Stimulating Hormone; Glycoprotein Hormones, alpha Sub

1991
Long-term follow-up of 'cured' prolactinoma patients after successful adenomectomy.
    Clinical endocrinology, 1990, Volume: 32, Issue:5

    Topics: Adenoma; Adrenalectomy; Adult; Domperidone; Dopamine Antagonists; Female; Follow-Up Studies; Humans;

1990