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domperidone and Adenohypophyseal Diseases

domperidone has been researched along with Adenohypophyseal Diseases in 5 studies

Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.

Research Excerpts

ExcerptRelevanceReference
"Fifteen normal menstruating women in the early follicular phase of their menstrual cycle, fifteen patients with prolactin secreting adenomas, two patients with a suprahypophysial lesion and an hyperprolactinemia, underwent a dopamine infusion (4 micrograms/kg/mn for four hours and an orally administration of domperidone (40 mg)."3.66[Kinetics of prolactinemia after withdrawal of dopamine perfusion and during the administration of domperidone. Normal and hyperprolactinemic subjects (prolactinomas and suprahypophyseal lesions)]. ( Bercovici, JP; Besson, G; Caroff, J; Khoury, S; Tater, D, 1983)
"Domperidone is a peripheral antagonist of dopamine which does not cross the blood-brain barrier."1.26[Domperidone: a new pharmacodynamic agent for exploration of the hypophysis (author's transl)]. ( Bercovici, JP; Besson, G; Caroff, J; Khoury, S; Sudre, Y; Tater, D, 1981)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19903 (60.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Beech, J1
McFarlane, D1
Lindborg, S1
Sojka, JE2
Boston, RC1
Miller, MA1
Pardo, ID1
Jackson, LP1
Moore, GE1
Bercovici, JP2
Khoury, S2
Tater, D2
Besson, G2
Caroff, J2
Webb, CB1
Thominet, JL1
Barowsky, H1
Berelowitz, M1
Frohman, LA1
Sudre, Y1

Other Studies

5 other studies available for domperidone and Adenohypophyseal Diseases

ArticleYear
α-Melanocyte--stimulating hormone and adrenocorticotropin concentrations in response to thyrotropin-releasing hormone and comparison with adrenocorticotropin concentration after domperidone administration in healthy horses and horses with pituitary pars i
    Journal of the American Veterinary Medical Association, 2011, May-15, Volume: 238, Issue:10

    Topics: Adrenocorticotropic Hormone; alpha-MSH; Animals; Domperidone; Dopamine Antagonists; Hormones; Horse

2011
Correlation of pituitary histomorphometry with adrenocorticotrophic hormone response to domperidone administration in the diagnosis of equine pituitary pars intermedia dysfunction.
    Veterinary pathology, 2008, Volume: 45, Issue:1

    Topics: Adrenocorticotropic Hormone; Animals; Domperidone; Dopamine Antagonists; Female; Horse Diseases; Hor

2008
[Kinetics of prolactinemia after withdrawal of dopamine perfusion and during the administration of domperidone. Normal and hyperprolactinemic subjects (prolactinomas and suprahypophyseal lesions)].
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 1983, Volume: 37, Issue:5

    Topics: Adenoma; Adult; Domperidone; Dopamine; Female; Follicular Phase; Humans; Kinetics; Pituitary Disease

1983
Evidence for lactotroph dopamine resistance in idiopathic hyperprolactinemia.
    The Journal of clinical endocrinology and metabolism, 1983, Volume: 56, Issue:6

    Topics: Adult; Bromocriptine; Domperidone; Dopamine; Dopamine Antagonists; Drug Resistance; Female; Humans;

1983
[Domperidone: a new pharmacodynamic agent for exploration of the hypophysis (author's transl)].
    La Nouvelle presse medicale, 1981, Jul-04, Volume: 10, Issue:29

    Topics: Benzimidazoles; Domperidone; Female; Growth Hormone; Humans; Male; Piperidines; Pituitary Diseases;

1981