domperidone has been researched along with Acute Lung Injury in 1 studies
Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.
Acute Lung Injury: A condition of lung damage that is characterized by bilateral pulmonary infiltrates (PULMONARY EDEMA) rich in NEUTROPHILS, and in the absence of clinical HEART FAILURE. This can represent a spectrum of pulmonary lesions, endothelial and epithelial, due to numerous factors (physical, chemical, or biological).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Domperidone treatment increased LPS-induced tumor necrosis factor (TNF) and interleukin (IL)-6 production in the bronchoalveolar lavage fluid, without altering tissue damage and the number of immune cells in the lungs and circulation." | 5.48 | Repeated Domperidone treatment modulates pulmonary cytokines in LPS-induced acute lung injury in mice. ( Barreto, TR; Costola-de-Souza, C; Felício, LF; Margatho, RO; Palermo-Neto, J; Queiroz-Hazarbassanov, N; Rodrigues, SC; Zager, A, 2018) |
| "Domperidone treatment increased LPS-induced tumor necrosis factor (TNF) and interleukin (IL)-6 production in the bronchoalveolar lavage fluid, without altering tissue damage and the number of immune cells in the lungs and circulation." | 1.48 | Repeated Domperidone treatment modulates pulmonary cytokines in LPS-induced acute lung injury in mice. ( Barreto, TR; Costola-de-Souza, C; Felício, LF; Margatho, RO; Palermo-Neto, J; Queiroz-Hazarbassanov, N; Rodrigues, SC; Zager, A, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barreto, TR | 1 |
| Costola-de-Souza, C | 1 |
| Margatho, RO | 1 |
| Queiroz-Hazarbassanov, N | 1 |
| Rodrigues, SC | 1 |
| Felício, LF | 1 |
| Palermo-Neto, J | 1 |
| Zager, A | 1 |
1 other study available for domperidone and Acute Lung Injury
| Article | Year |
|---|---|
Repeated Domperidone treatment modulates pulmonary cytokines in LPS-induced acute lung injury in mice.
Topics: Acute Lung Injury; Animals; Bronchoalveolar Lavage Fluid; Disease Progression; Domperidone; Dopamine | 2018 |