domperidone has been researched along with Acid Aspiration Syndrome in 2 studies
Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The domperidone group experienced significantly less dysphagia, nausea and vomiting, and aspiration pneumonia (P < 0." | 9.51 | Evaluation of domperidone efficacy to prevent aspiration pneumonia in patients with acute ischemic stroke: a randomized clinical trial. ( Allami, A; Kianimajd, S; Mavandadi, S; Paybast, S, 2022) |
| " The domperidone group experienced significantly less dysphagia, nausea and vomiting, and aspiration pneumonia (P < 0." | 5.51 | Evaluation of domperidone efficacy to prevent aspiration pneumonia in patients with acute ischemic stroke: a randomized clinical trial. ( Allami, A; Kianimajd, S; Mavandadi, S; Paybast, S, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Allami, A | 1 |
| Kianimajd, S | 1 |
| Mavandadi, S | 1 |
| Paybast, S | 1 |
| Turner, DA | 1 |
| Vickers, A | 1 |
| Smith, G | 1 |
2 trials available for domperidone and Acid Aspiration Syndrome
| Article | Year |
|---|---|
Evaluation of domperidone efficacy to prevent aspiration pneumonia in patients with acute ischemic stroke: a randomized clinical trial.
Topics: Aged; Aged, 80 and over; Domperidone; Female; Humans; Ischemic Stroke; Male; Middle Aged; Pneumonia; | 2022 |
Evaluation of the combined effects of atropine and domperidone on the lower oesophageal sphincter.
Topics: Adult; Atropine; Domperidone; Esophagogastric Junction; Humans; Pneumonia, Aspiration; Pressure | 1985 |