domperidone has been researched along with Abnormalities, Drug-Induced in 4 studies
Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.
Abnormalities, Drug-Induced: Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Domperidone is widely used during pregnancy, although the risks associated with pregnant women have not been adequately evaluated." | 8.02 | Risk of Pregnancy Termination and Congenital Anomalies After Domperidone Exposure: A Study in the EFEMERIS Database. ( Araujo, M; Benevent, J; Damase-Michel, C; Hurault-Delarue, C; Lacroix, I; Sommet, A; Vabre, C, 2021) |
| "The safety of domperidone in pregnancy remains unknown." | 7.79 | Fetal and neonatal outcomes in women taking domperidone during pregnancy. ( Ahn, HK; Choi, JS; Han, JY; Kim, MY; Koren, G; Nava-Ocampo, AA; Ryu, HM; Yang, JH, 2013) |
| "Domperidone is widely used during pregnancy, although the risks associated with pregnant women have not been adequately evaluated." | 4.02 | Risk of Pregnancy Termination and Congenital Anomalies After Domperidone Exposure: A Study in the EFEMERIS Database. ( Araujo, M; Benevent, J; Damase-Michel, C; Hurault-Delarue, C; Lacroix, I; Sommet, A; Vabre, C, 2021) |
| "The safety of domperidone in pregnancy remains unknown." | 3.79 | Fetal and neonatal outcomes in women taking domperidone during pregnancy. ( Ahn, HK; Choi, JS; Han, JY; Kim, MY; Koren, G; Nava-Ocampo, AA; Ryu, HM; Yang, JH, 2013) |
| "Migraine is a typical "women's disease": the fluctuations of sex hormones, in particular estrogens, during woman's reproductive life show a direct and major influence on migraine course." | 2.42 | [Migraine during pregnancy and lactation: treatment of the acute attack and non-pharmacological prophylactic strategies]. ( Airola, G; Allais, G; Benedetto, C; Bosio, A; Ciochetto, D; De Lorenzo, C; Mana, O; Quirico, PE; Terzi, MG, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ishikawa, T | 1 |
| Obara, T | 1 |
| Akazawa, M | 1 |
| Noda, A | 1 |
| Oyanagi, G | 1 |
| Morishita, K | 1 |
| Miyakoda, K | 1 |
| Nishigori, H | 1 |
| Kawame, H | 1 |
| Yaegashi, N | 1 |
| Kuriyama, S | 1 |
| Mano, N | 1 |
| Araujo, M | 1 |
| Vabre, C | 1 |
| Benevent, J | 1 |
| Sommet, A | 1 |
| Damase-Michel, C | 1 |
| Hurault-Delarue, C | 1 |
| Lacroix, I | 1 |
| Choi, JS | 1 |
| Han, JY | 1 |
| Ahn, HK | 1 |
| Ryu, HM | 1 |
| Kim, MY | 1 |
| Yang, JH | 1 |
| Nava-Ocampo, AA | 1 |
| Koren, G | 1 |
| Allais, G | 1 |
| Bosio, A | 1 |
| Mana, O | 1 |
| Airola, G | 1 |
| Ciochetto, D | 1 |
| Terzi, MG | 1 |
| De Lorenzo, C | 1 |
| Quirico, PE | 1 |
| Benedetto, C | 1 |
1 review available for domperidone and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
[Migraine during pregnancy and lactation: treatment of the acute attack and non-pharmacological prophylactic strategies].
Topics: Abnormalities, Drug-Induced; Acetaminophen; Acupuncture Points; Acupuncture Therapy; Adult; Analgesi | 2003 |
3 other studies available for domperidone and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
Risk of major congenital malformations associated with first-trimester exposure to propulsives: A health administrative database study in Japan.
Topics: Abnormalities, Drug-Induced; Databases, Factual; Domperidone; Female; Gastrointestinal Agents; Human | 2022 |
Risk of Pregnancy Termination and Congenital Anomalies After Domperidone Exposure: A Study in the EFEMERIS Database.
Topics: Abnormalities, Drug-Induced; Abortion, Induced; Domperidone; Female; Humans; Infant, Newborn; Pregna | 2021 |
Fetal and neonatal outcomes in women taking domperidone during pregnancy.
Topics: Abnormalities, Drug-Induced; Adult; Antiemetics; Birth Weight; Domperidone; Female; Fetal Developmen | 2013 |