domperidone has been researched along with Abdominal Pain in 3 studies
Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.
Abdominal Pain: Sensation of discomfort, distress, or agony in the abdominal region.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of the study was to evaluate the therapeutic effect of domperidone on children with abdominal pain predominant functional gastrointestinal disorders (AP-FGIDs)." | 9.27 | Randomized Controlled Clinical Trial on Value of Domperidone in Functional Abdominal Pain in Children. ( de Silva, A; Devanarayana, NM; Gunawardena, S; Karunanayake, A; Rajindrajith, S, 2018) |
| "Our aim was to determine whether domperidone could improve the symptoms of patients with gastroparesis, accelerate gastric emptying, and enhance quality of life." | 7.69 | The effect of chronic oral domperidone therapy on gastrointestinal symptoms, gastric emptying, and quality of life in patients with gastroparesis. ( McCallum, RW; Sarosiek, I; Soykan, I, 1997) |
| "The aim of the study was to evaluate the therapeutic effect of domperidone on children with abdominal pain predominant functional gastrointestinal disorders (AP-FGIDs)." | 5.27 | Randomized Controlled Clinical Trial on Value of Domperidone in Functional Abdominal Pain in Children. ( de Silva, A; Devanarayana, NM; Gunawardena, S; Karunanayake, A; Rajindrajith, S, 2018) |
| "Our aim was to determine whether domperidone could improve the symptoms of patients with gastroparesis, accelerate gastric emptying, and enhance quality of life." | 3.69 | The effect of chronic oral domperidone therapy on gastrointestinal symptoms, gastric emptying, and quality of life in patients with gastroparesis. ( McCallum, RW; Sarosiek, I; Soykan, I, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Karunanayake, A | 1 |
| Devanarayana, NM | 1 |
| de Silva, A | 1 |
| Gunawardena, S | 1 |
| Rajindrajith, S | 1 |
| Ramos, L | 1 |
| Alarcón, O | 1 |
| Adrian, Z | 1 |
| Gimeno-García, AZ | 1 |
| Nicolás-Pérez, D | 1 |
| Jiménez-Sosa, A | 1 |
| Quintero, E | 1 |
| Soykan, I | 1 |
| Sarosiek, I | 1 |
| McCallum, RW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| An Investigational New Drug Program for the Use of Domperidone in the Treatment of Refractory Gastroesophageal Reflux Disease and Other Gastrointestinal Motility Disorders[NCT00777439] | 75 participants (Anticipated) | Interventional | 2008-10-31 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for domperidone and Abdominal Pain
| Article | Year |
|---|---|
Randomized Controlled Clinical Trial on Value of Domperidone in Functional Abdominal Pain in Children.
Topics: Abdominal Pain; Child; Child, Preschool; Domperidone; Dopamine Antagonists; Double-Blind Method; Fem | 2018 |
One-day versus two-day cleansing for colon capsule endoscopy: a prospective randomized pilot study.
Topics: Abdominal Pain; Adult; Aged; Bisacodyl; Capsule Endoscopy; Cathartics; Colon; Dietary Fiber; Domperi | 2014 |
1 other study available for domperidone and Abdominal Pain
| Article | Year |
|---|---|
The effect of chronic oral domperidone therapy on gastrointestinal symptoms, gastric emptying, and quality of life in patients with gastroparesis.
Topics: Abdominal Pain; Administration, Oral; Adult; Aged; Antiemetics; Domperidone; Dopamine Antagonists; E | 1997 |