Page last updated: 2024-10-26

domperidone and 2019 Novel Coronavirus Disease

domperidone has been researched along with 2019 Novel Coronavirus Disease in 1 studies

Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.

Research Excerpts

ExcerptRelevanceReference
"Domperidone has shown in vitro antiviral activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and potential immudolatory properties through the stimulation of prolactin secretion."3.30A randomized, double-blind study on the efficacy of oral domperidone versus placebo for reducing SARS-CoV-2 viral load in mild-to-moderate COVID-19 patients in primary health care. ( Abad Esteban, AM; Arias de Saavedra Criado, MI; Blanco Gallego, AM; Campo Martos, I; Díaz Martín, R; Fernández Rodríguez, Á; García Pérez, L; Gijón Seco, MT; Gil, C; Guirao Sánchez, C; Herrero Vanrell, P; Izquierdo Zamarriego, MJ; Juárez Antón, S; López Gómez, V; López Valero, RM; Martín Alegre, C; Martínez Álvarez, MÁ; Martínez, A; Mestre de Juan, M; Mielgo Salvador, R; Molina Barcena, V; Montegrifo Rentero, VM; Montilla Bernabé, A; Navarro Pablos, M; Navas de la Peña, B; Ortiz Zamorano, S; Rabanal Basalo, A; Revuelta Puigdollers, ML; Rodríguez Jiménez, ME; Saníger Herrera, JM; Santa Cruz Hernández, J; Sarriá Sánchez, MT; Simón Miguel, L; Soler López, B; Vaquero Vinent, A; Vázquez Carrión, I; Viejo Pinero, N; Vila Méndez, ML; Villanueva Morán, MDP, 2023)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
Rabanal Basalo, A1
Navarro Pablos, M1
Viejo Pinero, N1
Vila Méndez, ML1
Molina Barcena, V1
Montilla Bernabé, A1
Villanueva Morán, MDP1
Blanco Gallego, AM1
Guirao Sánchez, C1
Juárez Antón, S1
Fernández Rodríguez, Á1
Revuelta Puigdollers, ML1
Sarriá Sánchez, MT1
Martín Alegre, C1
Martínez Álvarez, MÁ1
Mestre de Juan, M1
Mielgo Salvador, R1
Gijón Seco, MT1
Saníger Herrera, JM1
Rodríguez Jiménez, ME1
Navas de la Peña, B1
Santa Cruz Hernández, J1
Abad Esteban, AM1
Díaz Martín, R1
García Pérez, L1
Herrero Vanrell, P1
Arias de Saavedra Criado, MI1
Vaquero Vinent, A1
López Gómez, V1
Montegrifo Rentero, VM1
Simón Miguel, L1
Campo Martos, I1
Ortiz Zamorano, S1
Izquierdo Zamarriego, MJ1
Vázquez Carrión, I1
López Valero, RM1
Gil, C1
Martínez, A1
Soler López, B1

Trials

1 trial available for domperidone and 2019 Novel Coronavirus Disease

ArticleYear
A randomized, double-blind study on the efficacy of oral domperidone versus placebo for reducing SARS-CoV-2 viral load in mild-to-moderate COVID-19 patients in primary health care.
    Annals of medicine, 2023, Volume: 55, Issue:2

    Topics: Antiviral Agents; COVID-19; Domperidone; Double-Blind Method; Humans; Primary Health Care; SARS-CoV-

2023