Page last updated: 2024-08-21

docusate and Constipation

docusate has been researched along with Constipation in 49 studies

Research

Studies (49)

Timeframe	Studies, this research(%)	All Research%
pre-1990	19 (38.78)	18.7374
1990's	4 (8.16)	18.2507
2000's	3 (6.12)	29.6817
2010's	16 (32.65)	24.3611
2020's	7 (14.29)	2.80

Authors

Authors	Studies
Coulson, EE; Jierjian, E; Lam, T; Walden, SG; Yang, A	1
Coughlin, AC; Dubois, B; Romanova, A; Woodbury, CF	1
Ahlawat, S; Atkin, S; Donnelly, J; Kaye, AJ; Ziobro, A	1
Ballou, S; Camilleri, M; Lembo, A; Rangan, V; Shin, A	1
Almario, CV; Fuller, G; Khalil, C; Nag, A; Oh, SJ; Patel, D; Spalding, W; Spiegel, BMR	1
Engle, AL; Winans, ARM	1
Campbell, RE; Giunta, NJ; Londahl-Ramsey, VE; Pepe, MD; Tjoumakaris, FP; Tucker, BS; Weekes, DG	1
Bresee, L; Guirguis, M; Pasay, D; Shkrobot, R; Slobodan, J	1
Fakheri, RJ; Volpicelli, FM	1
Frisoli, TM; Makani, H; Sherrid, MV; Swistel, DG	1
Cummings, G; Hunter, K; Lazarescu, A; Ruston, T	1
Fedorak, RN; Paré, P	1
Asgrimsdottir, GM; Bjornsson, ES; Loftsson, T; Lund, SH; Ormarsson, OT; Stefansson, E	1
Cavalcanti, RB; Kamali, R; MacMillan, TE	1
Bonnici, A; Lee, TC; McDonald, EG; Tamblyn, R	1
Dieter, AA; Edenfield, AL; Garrett, MA; Siddiqui, NY; Visco, AG; Wu, JM	1
Bekkali, NL; Benninga, MA; Bongers, ME; Dijkgraaf, MG; Liem, O; van den Berg, MM; van Wijk, MP	1
LaSala, CA; O'Sullivan, DM; Patel, M; Schimpf, MO	1
Ali, SA; Barde, CJ; Kibria, R	1
Ahmedzai, SH; Boland, J	1
Bennett, MI; Bruera, E; De Lima, L; Nekolaichuk, C; Ripamonti, CI; Vignaroli, E; Wenk, R	1
Spooner, GR; Szafran, O; Tarumi, Y; Wilson, MP	1
Clark, K; Currow, DC	1
Sykes, N	1
MALOW, L; SPIESMAN, MG	1
BRODERS, AC	1
HARRIS, R	1
LAMPHIER, TA	1
SOCHA, ES	1
PHELPS, DK	1
WILSON, AK	1
STALTER, RJ	1
GIBSON, JH; HOSP, PH; LOWE, KJ; SMIGEL, JO	1
ANDER, L	1
GIFFONIELLO, AA	1
BRUSCH, CA	1
ELIAS, RA; VOGEL, J; WEYBREW, BB	1
DICKINSON, DG; WILSON, JL	1
Byeon, JJ; Hawley, PH	1
Jones, SR; Maslen, D	1
Sykes, NP	1
Daggy, BP; Diersing, PS; McRorie, JW; Miner, PB; Morel, JG; Robinson, M	1
Hurdon, V; Schroder, C; Viola, R	1
Godding, EW; Russel, RI	1
Dorton, K; Fain, AM; Herring, M; Susat, R	1
Clayden, GS	1
Corman, ML	1
Maddi, VI	1
Cantrell, M; Castle, SC; Israel, DS; Samuelson, MJ	1

Reviews

7 review(s) available for docusate and Constipation

Article	Year
Prevention of Postoperative Constipation in Urogynecology Patients: A Systematic Review. Urogynecology (Philadelphia, Pa.), 2023, 02-01, Volume: 29, Issue:2 Topics: Adult; Constipation; Defecation; Dioctyl Sulfosuccinic Acid; Humans; Laxatives	2023
Rethinking Docusate's Role in Opioid-Induced Constipation: A Critical Analysis of the Evidence. Journal of pain & palliative care pharmacotherapy, 2021, Volume: 35, Issue:1 Topics: Analgesics, Opioid; Constipation; Dioctyl Sulfosuccinic Acid; Humans; Opioid-Induced Constipation	2021
Efficacy and side-effect profiles of lactulose, docusate sodium, and sennosides compared to PEG in opioid-induced constipation: a systematic review. Canadian oncology nursing journal = Revue canadienne de nursing oncologique, 2013,Autumn, Volume: 23, Issue:4 Topics: Adult; Analgesics, Opioid; Cathartics; Constipation; Dioctyl Sulfosuccinic Acid; Humans; Lactulose; Laxatives; Polyethylene Glycols; Senna Extract; Surface-Active Agents	2013
Systematic review of stimulant and nonstimulant laxatives for the treatment of functional constipation. Canadian journal of gastroenterology & hepatology, 2014, Volume: 28, Issue:10 Topics: Bisacodyl; Canada; Citrates; Constipation; Dioctyl Sulfosuccinic Acid; Humans; Lactulose; Laxatives; Magnesium Oxide; Organometallic Compounds; Paraffin; Picolines; Polyethylene Glycols; Psyllium; Randomized Controlled Trials as Topic; Treatment Outcome	2014
Constipation in people prescribed opioids. BMJ clinical evidence, 2010, Apr-06, Volume: 2010 Topics: Analgesics, Opioid; Constipation; Dioctyl Sulfosuccinic Acid; Humans; Lactulose; Laxatives	2010
Current approaches to the management of constipation. Cancer surveys, 1994, Volume: 21 Topics: Cathartics; Clinical Trials as Topic; Constipation; Dioctyl Sulfosuccinic Acid; Humans; Lactulose; Neoplasms; Palliative Care; Research	1994
How useful is docusate in patients at risk for constipation? A systematic review of the evidence in the chronically ill. Journal of pain and symptom management, 2000, Volume: 19, Issue:2 Topics: Adolescent; Adult; Aged; Chronic Disease; Constipation; Dioctyl Sulfosuccinic Acid; Humans; Middle Aged; Randomized Controlled Trials as Topic; Risk Factors; Surface-Active Agents	2000

Trials

9 trial(s) available for docusate and Constipation

Article	Year
The efficacy of docusate sodium and senna glycoside for the treatment of constipation after rotator cuff repair: A randomized controlled study. Journal of the American Association of Nurse Practitioners, 2021, Feb-18, Volume: 34, Issue:1 Topics: Constipation; Dioctyl Sulfosuccinic Acid; Humans; Quality of Life; Rotator Cuff; Sennosides; Treatment Outcome	2021
Free fatty acid suppositories are as effective as docusate sodium and sorbitol enemas in treating constipation in children. Acta paediatrica (Oslo, Norway : 1992), 2016, Volume: 105, Issue:6 Topics: Administration, Rectal; Cathartics; Child; Child, Preschool; Constipation; Defecation; Dioctyl Sulfosuccinic Acid; Enema; Fatty Acids, Nonesterified; Female; Humans; Infant; Male; Sorbitol; Suppositories; Surface-Active Agents	2016
Polyethylene Glycol 3350 and Docusate Sodium Compared With Docusate Sodium Alone After Urogynecologic Surgery: A Randomized Controlled Trial. Obstetrics and gynecology, 2016, Volume: 128, Issue:3 Topics: Aged; Constipation; Defecation; Dioctyl Sulfosuccinic Acid; Double-Blind Method; Drug Therapy, Combination; Fecal Incontinence; Female; Gynecologic Surgical Procedures; Humans; Middle Aged; Pelvic Organ Prolapse; Polyethylene Glycols; Postoperative Period; Surface-Active Agents; Time Factors; Treatment Outcome; Urinary Incontinence; Urologic Surgical Procedures	2016
Rectal fecal impaction treatment in childhood constipation: enemas versus high doses oral PEG. Pediatrics, 2009, Volume: 124, Issue:6 Topics: Administration, Oral; Child; Child, Preschool; Constipation; Dioctyl Sulfosuccinic Acid; Dose-Response Relationship, Drug; Enema; Fecal Impaction; Fecal Incontinence; Female; Gastrointestinal Transit; Humans; Male; Polyethylene Glycols; Prospective Studies; Treatment Outcome	2009
The use of senna with docusate for postoperative constipation after pelvic reconstructive surgery: a randomized, double-blind, placebo-controlled trial. American journal of obstetrics and gynecology, 2010, Volume: 202, Issue:5 Topics: Citric Acid; Constipation; Dioctyl Sulfosuccinic Acid; Double-Blind Method; Gynecologic Surgical Procedures; Humans; Laxatives; Organometallic Compounds; Pelvic Floor; Phytotherapy; Postoperative Complications; Senna Plant; Surface-Active Agents	2010
Randomized, double-blind, placebo-controlled trial of oral docusate in the management of constipation in hospice patients. Journal of pain and symptom management, 2013, Volume: 45, Issue:1 Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Constipation; Dioctyl Sulfosuccinic Acid; Double-Blind Method; Drug Therapy, Combination; Female; Hospice Care; Humans; Laxatives; Male; Middle Aged; Senna Extract; Treatment Outcome	2013
Psyllium is superior to docusate sodium for treatment of chronic constipation. Alimentary pharmacology & therapeutics, 1998, Volume: 12, Issue:5 Topics: Adult; Aged; Cathartics; Chronic Disease; Constipation; Dioctyl Sulfosuccinic Acid; Double-Blind Method; Female; Humans; Male; Middle Aged; Psyllium	1998
Treatment of constipation in geriatric and chronically ill patients: a comparison. Southern medical journal, 1978, Volume: 71, Issue:6 Topics: Aged; Chronic Disease; Clinical Trials as Topic; Constipation; Dioctyl Sulfosuccinic Acid; Female; Humans; Male; Placebos; Succinates	1978
Constipation prevention: empiric use of stool softeners questioned. Geriatrics, 1991, Volume: 46, Issue:11 Topics: Aged; Aged, 80 and over; Cathartics; Constipation; Defecation; Dioctyl Sulfosuccinic Acid; Double-Blind Method; Female; Humans; Male; Nursing Homes	1991

Other Studies

33 other study(ies) available for docusate and Constipation

Article	Year
An Evaluation of Docusate Monotherapy and the Prevention of Opioid-Induced Constipation after Surgery. Journal of pain & palliative care pharmacotherapy, 2022, Volume: 36, Issue:1 Topics: Analgesics, Opioid; Cohort Studies; Constipation; Dioctyl Sulfosuccinic Acid; Humans; Laxatives; Opioid-Induced Constipation; Retrospective Studies	2022
Analysis of the economic burden of docusate sodium at a United States tertiary care center. Hospital practice (1995), 2023, Volume: 51, Issue:3 Topics: Constipation; Dioctyl Sulfosuccinic Acid; Drug Costs; Drug Prescriptions; Humans; Laxatives; Tertiary Care Centers; United States	2023
Use of Treatments for Irritable Bowel Syndrome and Patient Satisfaction Based on the IBS in America Survey. Gastroenterology, 2020, Volume: 158, Issue:3 Topics: Attitude of Health Personnel; Constipation; Diarrhea; Diet; Dietary Fiber; Dietary Supplements; Dioctyl Sulfosuccinic Acid; Female; Gastrointestinal Agents; Health Care Surveys; Humans; Irritable Bowel Syndrome; Laxatives; Lubiprostone; Male; Middle Aged; Parasympatholytics; Patient Satisfaction; Probiotics; Rifaximin	2020
Chronic Constipation in the United States: Results From a Population-Based Survey Assessing Healthcare Seeking and Use of Pharmacotherapy. The American journal of gastroenterology, 2020, Volume: 115, Issue:6 Topics: Adult; Age Factors; Bisacodyl; Chronic Disease; Colonoscopy; Constipation; Dietary Fiber; Dioctyl Sulfosuccinic Acid; Emergency Service, Hospital; Employment; Ethnicity; Female; Gastroenterologists; Gastrointestinal Agents; Guanylyl Cyclase C Agonists; Humans; Insurance, Health; Internal-External Control; Lactulose; Laxatives; Male; Marital Status; Middle Aged; Nonprescription Drugs; Patient Acceptance of Health Care; Peptides; Physicians, Primary Care; Polyethylene Glycols; Sennosides; Severity of Illness Index; Sex Factors; Surface-Active Agents; Surveys and Questionnaires; United States	2020
Association of Dissemination of an Educational Communication Tool With Docusate Administration. JAMA internal medicine, 2017, 10-01, Volume: 177, Issue:10 Topics: Alberta; Constipation; Dioctyl Sulfosuccinic Acid; Follow-Up Studies; Health Knowledge, Attitudes, Practice; Humans; Incidence; Information Dissemination; Medication Adherence; Retrospective Studies; Surface-Active Agents; Time Factors	2017
Things We Do for No Reason: Prescribing Docusate for Constipation in Hospitalized Adults. Journal of hospital medicine, 2019, Volume: 14, Issue:2 Topics: Aged, 80 and over; Constipation; Deprescriptions; Dioctyl Sulfosuccinic Acid; Female; Hospitals; Humans; Randomized Controlled Trials as Topic	2019
Wretched excess: stool-softener abuse and cardiogenic shock. The American journal of medicine, 2013, Volume: 126, Issue:9 Topics: Cardiomyopathy, Hypertrophic; Combined Modality Therapy; Constipation; Diagnosis, Differential; Dioctyl Sulfosuccinic Acid; Echocardiography; Electrocardiography; Female; Humans; Middle Aged; Schizophrenia; Shock, Cardiogenic; Surface-Active Agents	2013
Missed Opportunity to Deprescribe: Docusate for Constipation in Medical Inpatients. The American journal of medicine, 2016, Volume: 129, Issue:9 Topics: Aged; Constipation; Deprescriptions; Dioctyl Sulfosuccinic Acid; Female; Hospitalization; Humans; Laxatives; Length of Stay; Male; Patient Discharge; Retrospective Studies	2016
Pattern of Inpatient Laxative Use: Waste Not, Want Not. JAMA internal medicine, 2016, 08-01, Volume: 176, Issue:8 Topics: Constipation; Diagnosis, Differential; Diarrhea; Dioctyl Sulfosuccinic Acid; Enterocolitis, Pseudomembranous; Hospitalization; Humans; Inventories, Hospital; Laxatives; Nursing Service, Hospital; Pharmacy Service, Hospital; Polypharmacy; Practice Patterns, Physicians'; Quebec; Surface-Active Agents	2016
Gone but not forgotten. "Bubble gum enema" containing hydrogen peroxide and causing life-threatening colitis. Gastrointestinal endoscopy, 2010, Volume: 72, Issue:3 Topics: Anti-Infective Agents, Local; Biopsy; Colitis; Colonoscopy; Constipation; Dioctyl Sulfosuccinic Acid; Enema; Gastrointestinal Hemorrhage; Humans; Hydrogen Peroxide; Intestinal Mucosa; Male; Middle Aged; Phosphates; Reactive Oxygen Species; Surface-Active Agents; Ulcer	2010
Strategic pain management: the identification and development of the IAHPC opioid essential prescription package. Journal of palliative medicine, 2012, Volume: 15, Issue:2 Topics: Analgesics, Opioid; Antiemetics; Clinical Protocols; Constipation; Delphi Technique; Dioctyl Sulfosuccinic Acid; Drug Administration Schedule; Drug Therapy, Combination; Drugs, Essential; HIV Infections; Humans; Laxatives; Metoclopramide; Morphine; Nausea; Neoplasms; Pain Management; Palliative Care; Senna Extract	2012
Re: oral docusate in the management of constipation in hospice patients. Journal of pain and symptom management, 2012, Volume: 44, Issue:6 Topics: Constipation; Dioctyl Sulfosuccinic Acid; Female; Humans; Laxatives; Male	2012
Emerging evidence on docusate: commentary on Tarumi et al. Journal of pain and symptom management, 2013, Volume: 45, Issue:1 Topics: Constipation; Dioctyl Sulfosuccinic Acid; Female; Humans; Laxatives; Male	2013
New fecal softener (doxinate) in the treatment of constipation. The Journal-lancet, 1956, Volume: 76, Issue:6 Topics: Constipation; Dioctyl Sulfosuccinic Acid; Humans; Laxatives; Succinates	1956
Clinical studies with dioctyl sodium sulfosuccinate plus cascara derivative; a new agent for the treatment of constipation. The American journal of digestive diseases, 1957, Volume: 2, Issue:9 Topics: Biomedical Research; Cathartics; Constipation; Dioctyl Sulfosuccinic Acid; Humans; Rhamnus; Sodium; Succinates; Surface-Active Agents	1957
Constipation in geriatrics; management with dioctyl sodium sulfosuccinate. The American journal of digestive diseases, 1957, Volume: 2, Issue:9 Topics: Aged; Constipation; Dioctyl Sulfosuccinic Acid; Disease Management; Geriatrics; Humans; Sodium; Succinates; Surface-Active Agents	1957
Peri-colace in the treatment of constipation. American journal of proctology, 1957, Volume: 8, Issue:6 Topics: Cathartics; Constipation; Dioctyl Sulfosuccinic Acid; Humans; Rhamnus	1957
Use of doxinate with danthron as withdrawal therapy in the treatment of chronic functional constipation. Journal - Michigan State Medical Society, 1957, Volume: 56, Issue:11 Topics: Anthraquinones; Constipation; Dioctyl Sulfosuccinic Acid; Humans; Surface-Active Agents	1957
Effect of dioctyl sodium sulfosuccinate on bowel function in mental patients. The Journal of the Indiana State Medical Association, 1958, Volume: 51, Issue:5 Topics: Cathartics; Constipation; Defecation; Dioctyl Sulfosuccinic Acid; Humans; Mental Disorders; Mentally Ill Persons; Sodium; Succinates	1958
Dioctyl sodium sulfosuccinate (doxinate) as an adjunct in the roentgenologic investigation of the gastrointestinal tract; a clinical study. The American journal of roentgenology, radium therapy, and nuclear medicine, 1958, Volume: 80, Issue:1 Topics: Cathartics; Constipation; Dioctyl Sulfosuccinic Acid; Gastrointestinal Tract; Humans; Radiography; Sodium; Succinates	1958
Dioctyl sodium sulfosuccinate; its use in the prevention of impaction in hospitalized mental patients. Pennsylvania medical journal (1928), 1958, Volume: 61, Issue:5 Topics: Cathartics; Constipation; Dioctyl Sulfosuccinic Acid; Gastrointestinal Diseases; Humans; Mental Disorders; Mentally Ill Persons; Sodium; Succinates	1958
Constipation in elderly patients; treatment with dioctyl sodium sulfosuccinate and dioctyl sodium sulfosuccinate plus peristim. Medical times, 1958, Volume: 86, Issue:12 Topics: Aged; Cathartics; Constipation; Dioctyl Sulfosuccinic Acid; Humans; Patients; Sodium; Succinates; Surface-Active Agents	1958
[Remarks on obstipation & its treatment with dioctyl sodium sulfosuccinate & casanthranol; experiences of a clinical trial]. Svenska lakartidningen, 1959, Feb-06, Volume: 56, Issue:6 Topics: Constipation; Dioctyl Sulfosuccinic Acid; Rhamnus; Sodium; Succinates	1959
A new bowel corrective in anorectal surgery. (A preliminary report). Current therapeutic research, clinical and experimental, 1961, Volume: 3 Topics: Anal Canal; Catecholamines; Constipation; Digestive System Surgical Procedures; Dioctyl Sulfosuccinic Acid; Humans; Intestine, Large; Intestines; Rectum	1961
Treatment of chronic functional constipation with dioctyl sodium sulfosuccinate and danthron. The Journal of the Indiana State Medical Association, 1959, Volume: 52 Topics: Anthraquinones; Cathartics; Constipation; Dioctyl Sulfosuccinic Acid; Humans; Sodium; Succinates	1959
Dioctyl sodium sulfosuccinate in the control of constipation. A study in submariners during prolonged cruise. United States Armed Forces medical journal, 1960, Volume: 11 Topics: Cathartics; Constipation; Dioctyl Sulfosuccinic Acid; Humans; Military Personnel; Sodium; Succinates; Surface-Active Agents	1960
Use of dioctyl sodium sulfosuccinate (aerosol O.T.) for severe constipation. Journal of the American Medical Association, 1955, May-28, Volume: 158, Issue:4 Topics: Aerosols; Constipation; Dioctyl Sulfosuccinic Acid; Humans; Sodium; Succinates	1955
A comparison of sennosides-based bowel protocols with and without docusate in hospitalized patients with cancer. Journal of palliative medicine, 2008, Volume: 11, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Anthraquinones; Constipation; Dioctyl Sulfosuccinic Acid; Female; Hospitalization; Humans; Laxatives; Male; Middle Aged; Neoplasms; Senna Extract; Sennosides; Surface-Active Agents; Treatment Outcome	2008
Constipation in the elderly. Journal of the American Geriatrics Society, 1994, Volume: 42, Issue:5 Topics: Aged; Cathartics; Constipation; Dioctyl Sulfosuccinic Acid; Humans	1994
Chronic constipation in childhood. Lancet (London, England), 1978, Jul-15, Volume: 2, Issue:8081 Topics: Age Factors; Child; Chronic Disease; Constipation; Dioctyl Sulfosuccinic Acid; Humans	1978
Dioctyl sodium sulphosuccinate in constipation. Lancet (London, England), 1978, Oct-07, Volume: 2, Issue:8093 Topics: Administration, Oral; Child; Constipation; Dioctyl Sulfosuccinic Acid; Drug Evaluation; Enema; Gastrointestinal Hemorrhage; Humans; Succinates	1978
Management of postoperative constipation in anorectal surgery. Diseases of the colon and rectum, 1979, Volume: 22, Issue:3 Topics: Adult; Aged; Anal Canal; Cathartics; Constipation; Dioctyl Sulfosuccinic Acid; Female; Glycosides; Humans; Male; Middle Aged; Peristalsis; Postoperative Complications; Rectum; Senna Extract; Succinates	1979
Regulation of bowel function by a laxative/stool softener preparation in aged nursing home patients. Journal of the American Geriatrics Society, 1979, Volume: 27, Issue:10 Topics: Aged; Cathartics; Constipation; Dietary Fiber; Dioctyl Sulfosuccinic Acid; Drug Combinations; Enema; Female; Humans; Male; Nursing Homes; Senna Extract	1979