Page last updated: 2024-09-03

dl 111-it and Pregnancy

dl 111-it has been researched along with Pregnancy in 15 studies

*Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. [MeSH]

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19908 (53.33)18.7374
1990's3 (20.00)18.2507
2000's4 (26.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Consonni, P; Galliani, G; Omodei-Salé, A1
Fang, RY; He, QJ; Wang, WF; Wu, HH; Yang, B1
Assandri, A; Ferrari, P; Galliani, G; Omodei-Salé, A; Perazzi, A; Ripamonti, A; Tuan, G; Zerilli, LF1
Assandri, A; Galliani, G; Omodei-Salé, A; Perazzi, A; Sartori, G1
Assandri, A; Galliani, G; Grant, AM; Lancini, G; Lerner, LJ; Nock, PE; Omodei-Salè, A1
Assandri, A; Galliani, G; Gallico, L; Lancini, G; Luzzani, F; Oldani, C; Omodei-Salè, A; Soffientini, A1
Galliani, G; Luzzani, F1
Fang, RY; Yang, B1
Bo, Y; Lin, C; Ruiying, F; Zhiping, G1
Fang, RY; He, QJ; Yang, B; Ying, Y1
Fang, RY; He, QJ; Yang, B; Zhou, HJ1
Fang, R; He, Q; Shentu, J; Wang, L; Zhou, H1
Fang, RY; Yang, BZ; Zhang, YP; Zhou, HJ1
Assandri, A; Barone, D; Colombo, G; Conz, A; Galliani, G; Lancini, GC; Luzzani, F; Mistrello, L1
Lerner, LJ1

Other Studies

15 other study(ies) available for dl 111-it and Pregnancy

ArticleYear
A new class of nonhormonal pregnancy-terminating agents. Synthesis and contragestational activity of 3,5-diaryl-s-triazoles.
    Journal of medicinal chemistry, 1983, Volume: 26, Issue:8

    Topics: Abortifacient Agents; Abortifacient Agents, Nonsteroidal; Animals; Cricetinae; Female; Pregnancy; Rats; Structure-Activity Relationship; Triazoles

1983
Synergistic effects of DL111-IT in combination with mifepristone and misoprostol on termination of early pregnancy in preclinical studies.
    Contraception, 2003, Volume: 68, Issue:4

    Topics: Abortifacient Agents, Nonsteroidal; Abortifacient Agents, Steroidal; Abortion, Induced; Animals; Columbidae; Drug Synergism; Drug Therapy, Combination; Female; Guinea Pigs; Male; Mice; Mifepristone; Misoprostol; Pregnancy; Pregnancy Trimester, First; Rats; Rats, Sprague-Dawley; Triazoles; Uterus; Vomiting

2003
Metabolic pathways of the contragestational agent, 3-(2-ethylphenyl)-5-(3-methoxyphenyl)-1H-1,2,4-triazole (DL 111-IT), in the rat.
    Xenobiotica; the fate of foreign compounds in biological systems, 1984, Volume: 14, Issue:6

    Topics: Abortifacient Agents; Animals; Bile; Chemical Phenomena; Chemistry; Feces; Female; Magnetic Resonance Spectroscopy; Pregnancy; Rats; Rats, Inbred Strains; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Triazoles

1984
Pharmacokinetics-activity relationships of a new non-hormonal antifertility agent: 3-(2-ethylphenyl)-5-(3-methoxyphenyl)-1H-1, 2,4-triazole, in the rat and the hamster.
    European journal of drug metabolism and pharmacokinetics, 1983, Volume: 8, Issue:1

    Topics: Animals; Contraceptives, Oral; Cricetinae; Female; Fertility; Half-Life; Kinetics; Mesocricetus; Pregnancy; Protein Binding; Rats; Rats, Inbred Strains; Species Specificity; Tissue Distribution; Triazoles

1983
DL 111, a new non-hormonal antifertility agent: contragestational and kinetic profile in baboons.
    Contraception, 1982, Volume: 26, Issue:2

    Topics: Abortifacient Agents; Animals; Female; Fetus; Gestational Age; Kinetics; Male; Menstruation; Papio; Pregnancy; Progesterone; Triazoles

1982
A new non-hormonal pregnancy-terminating agent.
    Contraception, 1981, Volume: 23, Issue:2

    Topics: Abortifacient Agents; Abortifacient Agents, Nonsteroidal; Adrenalectomy; Animals; Castration; Cricetinae; Dogs; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Hypophysectomy; Mice; Pregnancy; Pregnancy, Animal; Progesterone; Rats; Triazoles

1981
On the mechanism of action of a new pregnancy-terminating agent. Part I: Effects of prostaglandin F2 alpha metabolism in the rat and the hamster.
    Contraception, 1981, Volume: 23, Issue:3

    Topics: Abortifacient Agents; Animals; Cricetinae; Female; Lung; Placenta; Pregnancy; Prostaglandins F; Rats; Triazoles; Uterus

1981
Synergistic effects on pregnancy-termination activity of DL111-IT in combination with mifepristone.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1996, Volume: 17, Issue:4

    Topics: Abortifacient Agents, Nonsteroidal; Abortifacient Agents, Steroidal; Abortion, Induced; Animals; Cells, Cultured; Decidua; Drug Synergism; Female; Humans; Mifepristone; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Progesterone; Triazoles; Uterus

1996
Luteolytic effects of DL111-IT in pregnant rats.
    European journal of pharmacology, 1999, Sep-10, Volume: 380, Issue:2-3

    Topics: 20-alpha-Hydroxysteroid Dehydrogenase; 20-Hydroxysteroid Dehydrogenases; 3-Hydroxysteroid Dehydrogenases; Abortifacient Agents, Nonsteroidal; Animals; Corpus Luteum; DNA; Female; Histocytochemistry; Luteolytic Agents; Male; Nucleosomes; Organ Size; Ovary; Pregnancy; Progesterone; Proteins; Rats; Rats, Sprague-Dawley; Triazoles

1999
Synergistic effects of DL111-IT combined with mifepristone on termination of early pregnancy in rhesus monkeys.
    Contraception, 2000, Volume: 62, Issue:4

    Topics: Abortifacient Agents, Nonsteroidal; Abortion, Induced; Abortion, Veterinary; Animals; Drug Synergism; Female; Macaca mulatta; Male; Mifepristone; Pregnancy; Triazoles

2000
Termination of early pregnancy in the mouse, rat and hamster with DL111-IT and RU486.
    Contraception, 2000, Volume: 62, Issue:4

    Topics: Abortifacient Agents, Nonsteroidal; Abortion, Induced; Abortion, Veterinary; Animals; Cricetinae; Female; Male; Mesocricetus; Mice; Mifepristone; Pregnancy; Rats; Rats, Sprague-Dawley; Triazoles

2000
Effects of DL111-IT or combined with RU486 on uterine polyamines biosynthesis in rats during early gestation.
    Contraception, 2001, Volume: 63, Issue:5

    Topics: Abortifacient Agents, Nonsteroidal; Abortifacient Agents, Steroidal; Abortion, Induced; Animals; Biogenic Polyamines; Decidua; Female; Histocytochemistry; Male; Mifepristone; Pregnancy; Random Allocation; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric; Triazoles; Uterus

2001
Embryotoxicity and teratogenicity of DL111-IT, an early pregnancy-terminating agent, in the subsequent gestation following administration in rats.
    Contraception, 1991, Volume: 43, Issue:3

    Topics: Abnormalities, Drug-Induced; Abortifacient Agents, Nonsteroidal; Animals; Embryonic and Fetal Development; Female; Incidence; Injections, Subcutaneous; Male; Mice; Pregnancy; Pregnancy, Animal; Rats; Rats, Inbred Strains; Triazoles

1991
On the mode of action of a new contragestational agent (DL 111-IT).
    Contraception, 1986, Volume: 33, Issue:3

    Topics: Abortifacient Agents, Nonsteroidal; Animals; Cricetinae; Decidua; DNA; Female; Follicle Stimulating Hormone; Glucosephosphate Dehydrogenase; Lactates; Lactic Acid; Luteinizing Hormone; Mesocricetus; Ornithine Decarboxylase; Placenta; Pregnancy; Prolactin; Protein Biosynthesis; Rats; Rats, Inbred Strains; Receptors, Progesterone; Regional Blood Flow; RNA; Triazoles; Uterus

1986
Development of novel embryotoxic compounds for interceptive fertility control in the dog.
    Journal of reproduction and fertility. Supplement, 1989, Volume: 39

    Topics: Abortifacient Agents; Abortifacient Agents, Nonsteroidal; Animals; Cricetinae; Dogs; Dose-Response Relationship, Drug; Female; Guinea Pigs; Indoles; Isoindoles; Isoquinolines; Pregnancy; Pregnancy, Animal; Rats; Time Factors; Triazoles

1989