Page last updated: 2024-08-20

ditiocarb and Chemical and Drug Induced Liver Injury

ditiocarb has been researched along with Chemical and Drug Induced Liver Injury in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199014 (58.33)18.7374
1990's4 (16.67)18.2507
2000's4 (16.67)29.6817
2010's2 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Badawy, MM; Gaafa, KM; Hamza, AA1
Carlson, GP1
Amin, A; Hamza, AA1
Meng, Q; Shen, C; Zhang, G; Zhang, H1
Masuda, Y; Murohashi, M; Nakayama, N; Yamaguchi, A1
Siegers, CP; Younes, M1
Gerhardt, H; Homann, J; Hopf, F1
Eade, OE; Lucas, K; Millward-Sadler, GH; Mitchell, J; Wright, R1
Masuda, Y; Nakayama, N1
Heidbüchel, K; Siegers, CP; Younes, M1
Frühling, A; Siegers, CP; Younes, M1
Hanzlik, RP; Traiger, GJ; Vyas, KP1
Hobara, T; Ishiyama, H; Ogino, K1
Delaney, J; Timbrell, JA1
Disilvestro, RA; Lee, HG; Rogers, DL1
Ford, JH; Gopinath, C1
Frimmer, M; Homann, J; Rufeger, U1
Hong, CB; Lee, CC; Minor, JL; Seifter, J; Short, RD; Winston, JM1
Farber, E; Popp, JA; Shinozuka, H1
Siegers, CP; Strubelt, O; Völpel, M1
Khan, S; Lauriault, VV; O'Brien, PJ1
Ishikawa, M; Nakamura, T; Okuyama, Y; Shinzawa, H; Takahashi, T; Togashi, H; Ukai, K; Wakabayashi, H; Yamada, N; Yong, H1
Masuda, Y; Nakayama, N; Yasoshima, M1

Other Studies

24 other study(ies) available for ditiocarb and Chemical and Drug Induced Liver Injury

ArticleYear
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
The protective effects of ascorbic acid, cimetidine, and nifedipine on diethyldithiocarbamate-induced hepatic toxicity in albino rats.
    Drug and chemical toxicology, 2011, Volume: 34, Issue:4

    Topics: Animals; Ascorbic Acid; Biomarkers; Calcium; Chemical and Drug Induced Liver Injury; Cimetidine; Cytochrome P-450 Enzyme System; Ditiocarb; Dose-Response Relationship, Drug; Glutathione; Lipid Peroxidation; Liver; Male; Malondialdehyde; Nifedipine; Oxidative Stress; Protective Agents; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Time Factors

2011
Effect of the inhibition of the metabolism of 4-vinylphenol on its hepatotoxicity and pneumotoxicity in rats and mice.
    Toxicology, 2002, Sep-30, Volume: 179, Issue:1-2

    Topics: Alkynes; Animals; Antidotes; Benzene Derivatives; Bronchoalveolar Lavage Fluid; Cell Count; Chemical and Drug Induced Liver Injury; Ditiocarb; Enzyme Inhibitors; Injections, Intraperitoneal; L-Lactate Dehydrogenase; Lung Diseases; Male; Mice; Mice, Inbred ICR; NAD; Phenols; Rats; Rats, Sprague-Dawley; Succinate Dehydrogenase

2002
Oxidative stress mediates drug-induced hepatotoxicity in rats: a possible role of DNA fragmentation.
    Toxicology, 2005, Mar-30, Volume: 208, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Antiviral Agents; Calcium; Chemical and Drug Induced Liver Injury; Diclofenac; Ditiocarb; DNA Fragmentation; Glutathione; Ketoconazole; Lipid Peroxidation; Liver; Male; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase; Toxicity Tests

2005
Isoniazid-induced hepatotoxicity in rat hepatocytes of gel entrapment culture.
    Toxicology letters, 2006, Nov-01, Volume: 167, Issue:1

    Topics: Acetylcysteine; Animals; Antidotes; Antitubercular Agents; Cell Survival; Cells, Cultured; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Ditiocarb; Female; Glutathione; Glycyrrhiza; Glycyrrhizic Acid; Hepatocytes; Isoniazid; Plant Extracts; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Serum Albumin

2006
The effects of diethyldithiocarbamate and carbon disulfide on acute nephrotoxicity induced by furan, bromobenzene and cephaloridine in mice.
    Japanese journal of pharmacology, 1984, Volume: 34, Issue:2

    Topics: Animals; Bromobenzenes; Carbon Disulfide; Carbon Tetrachloride Poisoning; Cephaloridine; Chemical and Drug Induced Liver Injury; Ditiocarb; Furans; Kidney; Kidney Diseases; Liver; Male; Mice; Mice, Inbred C57BL; Thiocarbamates

1984
Inhibition of the hepatotoxicity of paracetamol and its irreversible binding to rat liver microsomal protein.
    Archives of toxicology, 1980, Volume: 45, Issue:1

    Topics: Acetaminophen; Animals; Catechin; Chemical and Drug Induced Liver Injury; Deanol; Dimethyl Sulfoxide; Ditiocarb; In Vitro Techniques; Microsomes, Liver; Phenobarbital; Protein Binding; Rats; Time Factors

1980
[Protective and curative effects of diethyldithiocarbamate on galactosamine hepatitis in the rat (author's transl)].
    Arzneimittel-Forschung, 1980, Volume: 30, Issue:4

    Topics: Animals; Chemical and Drug Induced Liver Injury; Ditiocarb; Enzymes; Galactosamine; Male; Rats; Thiocarbamates

1980
Hepatic necrosis in rats following halothane administration: protective effect of diethyldithiocarbamate.
    Scandinavian journal of gastroenterology, 1980, Volume: 15, Issue:7

    Topics: Anesthesia, Inhalation; Animals; Chemical and Drug Induced Liver Injury; Ditiocarb; Halothane; Liver; Male; Necrosis; Rats; Thiocarbamates

1980
Protective effect of diethyldithiocarbamate and carbon disulfide against liver injury induced by various hepatotoxic agents.
    Biochemical pharmacology, 1982, Sep-01, Volume: 31, Issue:17

    Topics: Animals; Carbon Disulfide; Chemical and Drug Induced Liver Injury; Ditiocarb; Hexobarbital; Male; Mice; Mixed Function Oxygenases; Paralysis; Rats; Rats, Inbred Strains; Sleep; Thiocarbamates; Time Factors; Zoxazolamine

1982
Influence of alcohol, dithiocarb and (+)-catechin on the hepatotoxicity and metabolism of vinylidene chloride in rats.
    Journal of applied toxicology : JAT, 1983, Volume: 3, Issue:2

    Topics: Animals; Benzopyrans; Catechin; Chemical and Drug Induced Liver Injury; Dichloroethylenes; Ditiocarb; Drug Interactions; Ethanol; Hydrocarbons, Chlorinated; Liver; Male; Rats; Rats, Inbred Strains; Thiocarbamates; Water

1983
Influence of dithiocarb, (+)-catechin and silybine on halothane hepatotoxicity in the hypoxic rat model.
    Acta pharmacologica et toxicologica, 1983, Volume: 53, Issue:2

    Topics: Animals; Benzopyrans; Catechin; Chemical and Drug Induced Liver Injury; Ditiocarb; Flavonoids; Fluorides; Glutathione; Halothane; Liver; Male; Phenobarbital; Rats; Rats, Inbred Strains; Silymarin; Thiocarbamates

1983
Effect of thiocarbonyl compounds on alpha-naphthylisothiocyanate-induced hepatotoxicity and the urinary excretion of [35S]alpha-naphthylisothiocyanate in the rat.
    Toxicology and applied pharmacology, 1984, Mar-15, Volume: 72, Issue:3

    Topics: 1-Naphthylisothiocyanate; Animals; Chemical and Drug Induced Liver Injury; Disulfiram; Ditiocarb; Ethionamide; Male; Rats; Rats, Inbred Strains; Sulfates; Thiocarbamates; Thiocyanates

1984
Role of Kupffer cells in rat liver injury induced by diethyldithiocarbamate.
    European journal of pharmacology, 1995, Jan-13, Volume: 292, Issue:2

    Topics: Adenosine Triphosphate; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Dexamethasone; Dimethyl Sulfoxide; Ditiocarb; In Vitro Techniques; Kupffer Cells; Lipid Peroxidation; Male; Potassium; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Superoxides

1995
Role of cytochrome P450 in hydrazine toxicity in isolated hepatocytes in vitro.
    Xenobiotica; the fate of foreign compounds in biological systems, 1995, Volume: 25, Issue:12

    Topics: Acetone; Animals; Cells, Cultured; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Ditiocarb; Glutathione; Hydrazines; Isoenzymes; Isoniazid; L-Lactate Dehydrogenase; Liver; Liver Diseases; Male; Mixed Function Oxygenases; Oxidoreductases; Rats; Rats, Sprague-Dawley

1995
Diethyldithiocarbamate inhibition of galactosamine-induced hepatitis in rats.
    Pharmacological research, 2002, Volume: 45, Issue:3

    Topics: Acute Disease; Alanine Transaminase; Animals; Antioxidants; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Ditiocarb; Galactosamine; Glucuronidase; Male; Rats; Rats, Sprague-Dawley; Superoxide Dismutase

2002
The role of microsomal hydroxylases in the modification of chloroform hepatotoxicity in rats.
    British journal of experimental pathology, 1975, Volume: 56, Issue:5

    Topics: Animals; Carbon Disulfide; Chemical and Drug Induced Liver Injury; Chloroform; Chlorpromazine; DDT; Ditiocarb; Drug Interactions; Enzyme Induction; Female; Hexobarbital; Liver; Male; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases, N-Demethylating; Phenobarbital; Phenylbutazone; Proadifen; Rats; Sleep

1975
[Inhibition by diethyldithiocarbamate (DEDTC) of acute hepatotoxic effects induced by polyhalogenated hydrocarbons (PHHC)].
    Der Anaesthesist, 1976, Volume: 25, Issue:3

    Topics: Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chloroform; Ditiocarb; Glutathione; Halothane; Hydrocarbons, Halogenated; Liver Diseases; Male; Microcirculation; Perfusion; Phenobarbital; Rats; Thiocarbamates; Trichloroethylene

1976
Toxicity of vinylidene chloride in mice and rats and its alterations by various treatments.
    Journal of toxicology and environmental health, 1977, Volume: 3, Issue:5-6

    Topics: Animals; Chemical and Drug Induced Liver Injury; Dichloroethylenes; Ditiocarb; Environmental Exposure; Hydrocarbons, Chlorinated; Injections, Intraperitoneal; Kidney; Liver; Mice; Rats; Species Specificity; Thiram

1977
The protective effects of diethyldithiocarbamate and cycloheximide on the multiple hepatic lesions induced by carbon tetrachloride in the rat.
    Toxicology and applied pharmacology, 1978, Volume: 45, Issue:2

    Topics: Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cycloheximide; Ditiocarb; Liver; Male; Rats; Thiocarbamates; Time Factors

1978
The antihepatotoxic activity of dithiocarb as compared with six other thio compounds in mice.
    Archives of toxicology, 1978, Oct-13, Volume: 41, Issue:1

    Topics: Allyl Compounds; Aniline Hydroxylase; Animals; Bromobenzenes; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Dimethylnitrosamine; Ditiocarb; Male; Mice; Sulfhydryl Compounds; Sulfur; Thioacetamide; Thiocarbamates

1978
Hepatocyte cytotoxicity induced by various hepatotoxins mediated by cytochrome P-450IIE1: protection with diethyldithiocarbamate administration.
    Chemico-biological interactions, 1992, Volume: 81, Issue:3

    Topics: Animals; Carbon Disulfide; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; Disulfiram; Ditiocarb; Liver Diseases; Male; Microsomes, Liver; NADP; Oxidoreductases, N-Demethylating; Pyrazoles; Rats; Rats, Inbred Strains

1992
Superoxide is involved in the pathogenesis of paraquat-induced injury in cultured rat liver slices.
    Hepatology (Baltimore, Md.), 1991, Volume: 14, Issue:4 Pt 1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Culture Techniques; Ditiocarb; Drug Carriers; L-Lactate Dehydrogenase; Liposomes; Liver Diseases; Paraquat; Rats; Superoxide Dismutase

1991
The effects of diethyldithiocarbamate on the hepatotoxic action and antitumor activity of N-methylformamide in mice.
    Japanese journal of pharmacology, 1986, Volume: 40, Issue:4

    Topics: Animals; Antineoplastic Agents; Chemical and Drug Induced Liver Injury; Ditiocarb; Formamides; Glutathione; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred ICR; Species Specificity; Thiocarbamates; Time Factors

1986