ditiocarb has been researched along with Acquired Immunodeficiency Syndrome in 20 studies
*Acquired Immunodeficiency Syndrome: An acquired defect of cellular immunity associated with infection by the human immunodeficiency virus (HIV), a CD4-positive T-lymphocyte count under 200 cells/microliter or less than 14% of total lymphocytes, and increased susceptibility to opportunistic infections and malignant neoplasms. Clinical manifestations also include emaciation (wasting) and dementia. These elements reflect criteria for AIDS as defined by the CDC in 1993. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (55.00) | 18.7374 |
| 1990's | 7 (35.00) | 18.2507 |
| 2000's | 2 (10.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| De Guzman, RN; McDonnell, NB; Rice, WG; Summers, MF; Turpin, JA | 1 |
| Guedj, R | 1 |
| Chen, D; Cui, QC; Dou, QP; Pang, H | 1 |
| Funk, CY; Hersh, EM; Mosier, DE; Petersen, EA; Ryschon, KL | 1 |
| Abrams, D; Bartlett, J; Brewton, G; Galpin, J; Gill, P; Gorter, R; Gottlieb, M; Hersh, EM; Jonikas, JJ; Landesman, S | 1 |
| Bock, P; Dietrich, M; Ernst, M; Flad, HD; Kern, P; Reisinger, EC | 1 |
| Funk, CY; Hersh, EM; Mosier, DE; Petersen, EA | 1 |
| Coutance, F; Delsaux, MC; Falkenrodt, A; Lang, JM; Mace, B; Pompidou, A; Telvi, L | 1 |
| Lang, JM | 1 |
| Claussen, M; Dietrich, M; Hübner, C; Kohlschütter, A; Lehr, HA; Reisinger, EC; Schmitz, H; Zimmer, JP | 1 |
| Hersh, EM; Kaplan, CS; Petersen, EA; Yocum, D | 1 |
| Brewton, GW; Hersh, EM; Hollinger, B; Mansell, PW; Reuben, JM; Rios, A | 1 |
| Jones, MM; Topping, RJ | 1 |
| Brewton, GW; Darragh, MJ; Gorman, SR; Gschwind, CR; Hersh, EM; Petersen, EA; Reuben, JA; Yocum, DE | 1 |
| Volberding, PA; Wong, RJ | 1 |
| Aleksijevic, A; Falkenrodt, A; Lang, JM; Mayer, S; Oberling, F | 1 |
| Choutet, P; Falkenrodt, A; Herviou, L; Kirstetter, M; Lang, JM; Livrozet, JM; Retornaz, G; Touraine, F; Touraine, JL; Trepo, C | 1 |
| Charbonnier, C; Lemarie, E; Musset, M; Renoux, G; Renoux, M | 1 |
2 review(s) available for ditiocarb and Acquired Immunodeficiency Syndrome
| Article | Year |
|---|---|
[AIDS: ethics and scientific investigation on human beings].
Topics: Acquired Immunodeficiency Syndrome; Adenine; Animals; Anti-HIV Agents; Azathioprine; Clinical Trials as Topic; Congresses as Topic; Cyclosporine; Developing Countries; Ditiocarb; Double-Blind Method; Drug Evaluation, Preclinical; Drug Therapy, Combination; Ethics Committees, Research; Human Experimentation; Humans; Informed Consent; Mass Media; Oligodeoxyribonucleotides, Antisense; Organophosphonates; Practice Guidelines as Topic; Stavudine; Tenofovir; Thionucleotides | 2008 |
Immunological characteristics and potential approaches to immunotherapy of HIV infection.
Topics: Acquired Immunodeficiency Syndrome; Cytotoxicity, Immunologic; Ditiocarb; Humans; Immunotherapy; Leukocytes, Mononuclear | 1988 |
8 trial(s) available for ditiocarb and Acquired Immunodeficiency Syndrome
| Article | Year |
|---|---|
Multicenter, randomized, placebo-controlled study of ditiocarb (Imuthiol) in human immunodeficiency virus-infected asymptomatic and minimally symptomatic patients. The HIV87 Study Group.
Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; AIDS-Related Complex; CD4-Positive T-Lymphocytes; Ditiocarb; Female; HIV Infections; Humans; Leukocyte Count; Male; Middle Aged | 1993 |
Ditiocarb sodium (diethyldithiocarbamate) therapy in patients with symptomatic HIV infection and AIDS. A randomized, double-blind, placebo-controlled, multicenter study.
Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; CD4-Positive T-Lymphocytes; Ditiocarb; Double-Blind Method; Female; HIV Infections; Humans; Leukocyte Count; Male; Middle Aged; Opportunistic Infections; Placebos; Proportional Hazards Models | 1991 |
Inhibition of HIV progression by dithiocarb. German DTC Study Group.
Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Adult; Ditiocarb; Double-Blind Method; Drug Administration Schedule; Drug Evaluation; Follow-Up Studies; HIV-1; Humans; Injections, Intravenous; Leukocyte Count; Male; Middle Aged; Opportunistic Infections; Randomized Controlled Trials as Topic; T-Lymphocytes, Helper-Inducer; Time Factors | 1990 |
Biological activity of diethyldithiocarbamate (Ditiocarb, Imuthiol) in an animal model of retrovirus-induced immunodeficiency disease and in clinical trials in patients with HIV infection. The Ditiocarb Study Group.
Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Complex; Animals; Disease Models, Animal; Ditiocarb; Double-Blind Method; HIV Infections; Humans; Mice; Mice, Inbred C57BL; Murine Acquired Immunodeficiency Syndrome; Opportunistic Infections; Recurrence | 1990 |
A randomized, controlled dose response study of intravenous sodium diethyldithiocarbamate in patients with advanced human immunodeficiency virus infection.
Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Complex; Ditiocarb; Dose-Response Relationship, Drug; Drug Tolerance; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Randomized Controlled Trials as Topic | 1989 |
A pilot study of diethyldithiocarbamate in patients with acquired immune deficiency syndrome (AIDS) and the AIDS-related complex.
Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Chi-Square Distribution; Clinical Trials as Topic; Ditiocarb; Humans; Injections, Intravenous; Life Tables; Pilot Projects; Random Allocation; Survival Rate | 1989 |
Randomised, double-blind, placebo-controlled trial of ditiocarb sodium ('Imuthiol') in human immunodeficiency virus infection.
Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Adult; Clinical Trials as Topic; Ditiocarb; Double-Blind Method; Drug Administration Schedule; Drug Evaluation; HIV; HIV Seropositivity; Humans; Leukocyte Count; Lymphocytes; Random Allocation; Skin Tests | 1988 |
Clinical characterization of imuthiol.
Topics: Acquired Immunodeficiency Syndrome; Adjuvants, Immunologic; Adult; Aged; Arthritis, Rheumatoid; Bacterial Infections; Bronchiectasis; Bronchitis; Chronic Disease; Clinical Trials as Topic; Ditiocarb; Female; Humans; Male; Middle Aged; Neoplasms; T-Lymphocytes; Thiocarbamates; Tuberculosis, Pulmonary | 1986 |
10 other study(ies) available for ditiocarb and Acquired Immunodeficiency Syndrome
| Article | Year |
|---|---|
Zinc ejection as a new rationale for the use of cystamine and related disulfide-containing antiviral agents in the treatment of AIDS.
Topics: Acquired Immunodeficiency Syndrome; Amino Acid Sequence; Anti-HIV Agents; Capsid; Capsid Proteins; Cells, Cultured; Cystamine; Disulfiram; Ditiocarb; gag Gene Products, Human Immunodeficiency Virus; Gene Products, gag; Humans; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Thiamine; Viral Proteins; Zinc Fingers | 1997 |
Sodium diethyldithiocarbamate, an AIDS progression inhibitor and a copper-binding compound, has proteasome-inhibitory and apoptosis-inducing activities in cancer cells.
Topics: Acquired Immunodeficiency Syndrome; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Nucleus; Copper; Disease Progression; Ditiocarb; Female; Humans; Male; Prostatic Neoplasms; Proteasome Inhibitors; Solutions | 2007 |
Effective therapy of the LP-BM5 murine retrovirus-induced lymphoproliferative immunodeficiency disease with diethyldithiocarbamate.
Topics: Acquired Immunodeficiency Syndrome; Animals; Disease Models, Animal; Ditiocarb; Dose-Response Relationship, Drug; Mice; Mice, Inbred C57BL | 1991 |
Imuthiol for AIDS.
Topics: Acquired Immunodeficiency Syndrome; Ditiocarb; Humans | 1990 |
Isoprinosine and Imuthiol, two potentially active compounds in patients with AIDS-related complex symptoms.
Topics: Acquired Immunodeficiency Syndrome; Adult; Ditiocarb; Homosexuality; Humans; In Vitro Techniques; Inosine; Inosine Pranobex; Leukocyte Count; Lymphocyte Activation; Male; Phytohemagglutinins; T-Lymphocytes; T-Lymphocytes, Helper-Inducer; Thiocarbamates | 1985 |
[Imuthiol and human immunodeficiency virus infection].
Topics: Acquired Immunodeficiency Syndrome; Ditiocarb; Humans | 1989 |
Decreased plasma membrane fluidity of peripheral blood lymphocytes after diethyldithiocarbamate (DTC) therapy in HIV-infected patients.
Topics: Acquired Immunodeficiency Syndrome; Cell Membrane; Diphenylhexatriene; Ditiocarb; Fluorescent Dyes; Humans; Lymphocytes; Membrane Fluidity; Spectrometry, Fluorescence; Stearic Acids | 1989 |
Optimal dithiocarbamate structure for immunomodulator action.
Topics: Acquired Immunodeficiency Syndrome; Adjuvants, Immunologic; Animals; Ditiocarb; Half-Life; Humans; Hydrogen-Ion Concentration; Pyrrolidines; Structure-Activity Relationship; Thiocarbamates | 1988 |
Providing clinical pharmacy services in an AIDS--oncology ambulatory-care clinic.
Topics: Acquired Immunodeficiency Syndrome; Ditiocarb; Drug Labeling; Hospital Bed Capacity, 300 to 499; Humans; Neoplasms; Outpatient Clinics, Hospital; Patient Education as Topic; Pharmacists; Pharmacy Service, Hospital; San Francisco | 1988 |
Immunomodulation with diethyldithiocarbamate in patients with AIDS-related complex.
Topics: Acquired Immunodeficiency Syndrome; Adult; Ditiocarb; Humans; Hypersensitivity, Immediate; Immunity, Cellular; Male; Thiocarbamates | 1985 |