ditercalinium has been researched along with Leukemia L 1210 in 6 studies
ditercalinium: structure given in first source; RN given refers to parent cpd
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ditercalinium (NSC 366241) is a 7H-pyrido[4,3-c]carbazole dimer with a diethylbipiperidine rigid chain linking the two heterocyclic rings." | 1.28 | Synthesis and biological activity of new dimers in the 7H-pyrido[4,3-c] carbazole antitumor series. ( Barsi, MC; Garbay-Jaureguiberry, C; Jacquemin-Sablon, A; Le Pecq, JB; Roques, BP, 1992) |
| "Ditercalinium (NSC 335153) was synthesized as a bifunctional DNA intercalator." | 1.28 | Recognition by the DNA repair system of DNA structural alterations induced by reversible drug-DNA interactions. ( Esnault, C; Jones, B; Lambert, B; Le Pecq, JB; Roques, BP; Segal-Bendirdjian, E; Yeung, AT, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (50.00) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Esnault, C | 4 |
| Roques, BP | 6 |
| Jacquemin-Sablon, A | 2 |
| Le Pecq, JB | 6 |
| Garbay-Jaureguiberry, C | 2 |
| Barsi, MC | 2 |
| Lambert, B | 1 |
| Segal-Bendirdjian, E | 2 |
| Jones, B | 1 |
| Yeung, AT | 1 |
| Brown, SC | 1 |
| Coulaud, D | 1 |
| Mishal, Z | 1 |
| Markovits, J | 1 |
| Pommier, Y | 1 |
| Mattern, MR | 1 |
| Kohn, KW | 1 |
| Léon, P | 1 |
6 other studies available for ditercalinium and Leukemia L 1210
| Article | Year |
|---|---|
Effects of new antitumor bifunctional intercalators derived from 7H-pyridocarbazole on sensitive and resistant L 1210 cells.
Topics: Animals; Antineoplastic Agents; Carbazoles; Cell Division; Cell Survival; Drug Evaluation, Preclinic | 1984 |
Synthesis and biological activity of new dimers in the 7H-pyrido[4,3-c] carbazole antitumor series.
Topics: Animals; Antineoplastic Agents; Carbazoles; DNA, Neoplasm; Leukemia L1210; Mice; Mice, Inbred DBA; S | 1992 |
Recognition by the DNA repair system of DNA structural alterations induced by reversible drug-DNA interactions.
Topics: Animals; Carbazoles; DNA; DNA Repair; Drug Interactions; Drug Screening Assays, Antitumor; Endodeoxy | 1990 |
Selective alteration of mitochondrial function by Ditercalinium (NSC 335153), a DNA bisintercalating agent.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Carbazoles; Carbonyl Cyanide m-Chlorophenyl | 1990 |
Effects of the bifunctional antitumor intercalator ditercalinium on DNA in mouse leukemia L1210 cells and DNA topoisomerase II.
Topics: Amsacrine; Animals; Carbazoles; Cross-Linking Reagents; DNA Damage; DNA, Neoplasm; Etoposide; Interc | 1986 |
Modulation of the antitumor activity by methyl substitutions in the series of 7H-pyridocarbazole monomers and dimers.
Topics: Animals; Antineoplastic Agents; Carbazoles; DNA; Leukemia L1210; Mice; Structure-Activity Relationsh | 1987 |