Page last updated: 2024-10-26

disulfiram and Schizophrenia

disulfiram has been researched along with Schizophrenia in 24 studies

Schizophrenia: A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.

Research Excerpts

ExcerptRelevanceReference
"The most common conditions underlying catatonia are affective disorders followed by schizophrenia, but several medical conditions including intoxications affecting the central nervous system can also present with catatonic signs and symptoms."6.53Catatonia in disulfiram intoxication - a case report and a brief overview of the literature. ( Faludi, G; Gazdag, G; Milan, F; Takacs, R; Ungvari, GS, 2016)
"Although disulfiram and naltrexone have been approved by the Food and Drug Administration for the treatment of alcoholism, no medications have been approved for individuals with alcohol dependence and comorbid psychiatric disorders."5.12Naltrexone and disulfiram in patients with alcohol dependence and current depression. ( Carroll, K; Levinson, C; Nich, C; Petrakis, I; Poling, J; Ralevski, E; Rounsaville, B, 2007)
"The most common conditions underlying catatonia are affective disorders followed by schizophrenia, but several medical conditions including intoxications affecting the central nervous system can also present with catatonic signs and symptoms."2.53Catatonia in disulfiram intoxication - a case report and a brief overview of the literature. ( Faludi, G; Gazdag, G; Milan, F; Takacs, R; Ungvari, GS, 2016)
"The comorbid substance abuse will markedly affect the course of illness of schizophrenia."2.45Management of schizophrenia with substance use disorders. ( Caroff, S; Lybrand, J, 2009)
"Co-occurring substance use disorder is common among patients with schizophrenia, and its presence greatly worsens the course of schizophrenia."2.43Treatment of schizophrenia and comorbid substance abuse: pharmacologic approaches. ( Green, AI, 2006)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199011 (45.83)18.7374
1990's2 (8.33)18.2507
2000's9 (37.50)29.6817
2010's1 (4.17)24.3611
2020's1 (4.17)2.80

Authors

AuthorsStudies
Hahl-Häkkinen, L1
Rask, SM1
Solismaa, A1
Ruuhonen, S1
Leinonen, E1
Takacs, R1
Milan, F1
Ungvari, GS1
Faludi, G1
Gazdag, G1
Wobrock, T3
Soyka, M2
Lybrand, J1
Caroff, S1
HEATH, RG1
NESSELHOF, W1
BISHOP, MP1
BYERS, LW1
Petrakis, IL1
Nich, C2
Ralevski, E2
Green, AI3
Drake, RE1
Brunette, MF2
Noordsy, DL2
Petrakis, I1
Levinson, C1
Carroll, K1
Poling, J1
Rounsaville, B1
O'Keefe, C1
D'Amelio, R1
Falkai, P1
Sternberg, DE1
VanKammen, DP1
Lerner, P1
Bunney, WE1
Epstein, LH1
Auriol, B1
Bardou, E1
Lambic, C1
Brenner, LM1
Karper, LP1
Krystal, JH1
Beckmann, H1
Gilbert, JC1
Lamprecht, F1
Ban, TA1
Ewing, JA1
Mueller, RA1
Rouse, BA1
Silver, D1
Hotson, JR1
Langston, JW1
Kingsbury, SJ1
Salzman, C1
Israelstam, DM1

Reviews

10 reviews available for disulfiram and Schizophrenia

ArticleYear
Catatonia in disulfiram intoxication - a case report and a brief overview of the literature.
    Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology, 2016, Volume: 18, Issue:2

    Topics: Acetaldehyde Dehydrogenase Inhibitors; Catatonia; Disulfiram; Female; Humans; Mood Disorders; Psycho

2016
Pharmacotherapy of patients with schizophrenia and substance abuse.
    Expert opinion on pharmacotherapy, 2009, Volume: 10, Issue:3

    Topics: Alcohol Deterrents; Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; Diagnosis, Dual (

2009
Management of schizophrenia with substance use disorders.
    The Psychiatric clinics of North America, 2009, Volume: 32, Issue:4

    Topics: Antipsychotic Agents; Diagnosis, Dual (Psychiatry); Disulfiram; Humans; Psychotherapy; Schizophrenia

2009
Treatment of schizophrenia and comorbid substance abuse: pharmacologic approaches.
    The Journal of clinical psychiatry, 2006, Volume: 67 Suppl 7

    Topics: Alcohol Deterrents; Alcoholism; Antipsychotic Agents; Clozapine; Comorbidity; Diagnosis, Dual (Psych

2006
Substance abuse and schizophrenia: pharmacotherapeutic intervention.
    Journal of substance abuse treatment, 2008, Volume: 34, Issue:1

    Topics: Acamprosate; Alcohol Deterrents; Antipsychotic Agents; Clozapine; Disulfiram; Drug Interactions; Hum

2008
[Pharmacotherapy of schizophrenia and comorbid substance use disorder. A systematic review].
    Der Nervenarzt, 2008, Volume: 79, Issue:1

    Topics: Alcohol Deterrents; Alcoholism; Algorithms; Antidepressive Agents, Tricyclic; Antipsychotic Agents;

2008
Pharmacotherapy of schizophrenia with comorbid substance use disorder--reviewing the evidence and clinical recommendations.
    Progress in neuro-psychopharmacology & biological psychiatry, 2008, Aug-01, Volume: 32, Issue:6

    Topics: Alcohol Deterrents; Antidepressive Agents; Antipsychotic Agents; Combined Modality Therapy; Diagnosi

2008
The direct effects of compliance on health outcome.
    Health psychology : official journal of the Division of Health Psychology, American Psychological Association, 1984, Volume: 3, Issue:4

    Topics: Alcoholism; Chlorpromazine; Chorionic Gonadotropin; Clofibrate; Coronary Disease; Disulfiram; Drug T

1984
Epilepsy and schizophrenia: a neurochemical bridge.
    Journal of neural transmission, 1977, Volume: 40, Issue:2

    Topics: Amphetamine; Anticonvulsants; Brain; Butyrophenones; Disulfiram; Dopamine; Dopamine beta-Hydroxylase

1977
Alcoholism and schizophrenia: diagnostic and therapeutic considerations.
    Alcoholism, clinical and experimental research, 1977, Volume: 1, Issue:2

    Topics: Alcoholism; Brain; Disulfiram; Dopamine; Humans; Methyltyrosines; Metronidazole; NAD; Norepinephrine

1977

Trials

3 trials available for disulfiram and Schizophrenia

ArticleYear
Psychotic spectrum disorders and alcohol abuse: a review of pharmacotherapeutic strategies and a report on the effectiveness of naltrexone and disulfiram.
    Schizophrenia bulletin, 2006, Volume: 32, Issue:4

    Topics: Adult; Alcohol Deterrents; Alcoholism; Bipolar Disorder; Combined Modality Therapy; Comorbidity; Dia

2006
Naltrexone and disulfiram in patients with alcohol dependence and current depression.
    Journal of clinical psychopharmacology, 2007, Volume: 27, Issue:2

    Topics: Alcohol Deterrents; Alcoholism; Bipolar Disorder; Cocaine-Related Disorders; Comorbidity; Connecticu

2007
The direct effects of compliance on health outcome.
    Health psychology : official journal of the Division of Health Psychology, American Psychological Association, 1984, Volume: 3, Issue:4

    Topics: Alcoholism; Chlorpromazine; Chorionic Gonadotropin; Clofibrate; Coronary Disease; Disulfiram; Drug T

1984

Other Studies

12 other studies available for disulfiram and Schizophrenia

ArticleYear
Co-medication with disulfiram markedly increased serum clozapine levels: Two case reports.
    Journal of psychopharmacology (Oxford, England), 2023, Volume: 37, Issue:2

    Topics: Alcoholism; Antipsychotic Agents; Clozapine; Cytochrome P-450 CYP1A2; Disulfiram; Humans; Schizophre

2023
BEHAVIORAL AND METABOLIC CHANGES ASSOCIATED WITH ADMINISTRATION OF TETRAETHYLTHIURAM DISULFIDE (ANTABUSE).
    Diseases of the nervous system, 1965, Volume: 26

    Topics: Autonomic Nervous System; Blood Chemical Analysis; Body Weight; Disulfiram; Electroencephalography;

1965
Schizophrenia and co-occurring substance use disorder.
    The American journal of psychiatry, 2007, Volume: 164, Issue:3

    Topics: Acamprosate; Adult; Alcohol-Related Disorders; Antipsychotic Agents; Comorbidity; Diagnosis, Dual (P

2007
Schizophrenia: dopamine beta-hydroxylase activity and treatment response.
    Science (New York, N.Y.), 1982, Jun-25, Volume: 216, Issue:4553

    Topics: Antipsychotic Agents; Disulfiram; Dopamine beta-Hydroxylase; Fusaric Acid; Humans; Levodopa; Schizop

1982
Control experiment in man on the sedative effect of disulfiram, an inhibitor of dopamine-beta-hydroxylase.
    Biological psychiatry, 1980, Volume: 15, Issue:4

    Topics: Bipolar Disorder; Disulfiram; Dopamine beta-Hydroxylase; Humans; Norepinephrine; Psychomotor Agitati

1980
Short-term use of disulfiram with clozapine.
    Journal of clinical psychopharmacology, 1994, Volume: 14, Issue:3

    Topics: Adult; Alcoholism; Clozapine; Disulfiram; Drug Therapy, Combination; Humans; Male; Schizophrenia

1994
[Psychotropic drugs as tools for clinical research into schizophrenia (author's transl)].
    Fortschritte der Neurologie, Psychiatrie, und ihrer Grenzgebiete, 1978, Volume: 46, Issue:10

    Topics: Acute Disease; Amphetamines; Antipsychotic Agents; Apomorphine; Blood Platelets; Bromocriptine; Disu

1978
Psychological medicine. Drugs used in psychological medicine: pharmacological basis of treatment.
    British medical journal, 1976, Apr-10, Volume: 1, Issue:6014

    Topics: Adenosine Triphosphatases; Alcoholism; Antidepressive Agents, Tricyclic; Anxiety; Barbiturates; Brai

1976
Low levels of dopamine beta-hydroxylase and psychosis.
    The American journal of psychiatry, 1977, Volume: 134, Issue:8

    Topics: Adult; Central Nervous System; Disulfiram; Dopamine; Dopamine beta-Hydroxylase; Humans; Male; Placeb

1977
Disulfiram-induced encephalopathy.
    Archives of neurology, 1976, Volume: 33, Issue:2

    Topics: Adult; Alcoholism; Brain Diseases; Disulfiram; Humans; Male; Middle Aged; Psychoses, Substance-Induc

1976
Disulfiram in the treatment of alcoholic patients with schizophrenia.
    Hospital & community psychiatry, 1990, Volume: 41, Issue:2

    Topics: Alcoholism; Disulfiram; Humans; Schizophrenia

1990
From medical physicist to psychopharmacologist: a neo-renaissance interdisciplinary evolution of.
    Perspectives in biology and medicine, 1972,Spring, Volume: 15, Issue:3

    Topics: Dihydroxyphenylalanine; Disulfiram; Electroconvulsive Therapy; Enzyme Induction; History, 20th Centu

1972