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disulfiram and Pregnancy

disulfiram has been researched along with Pregnancy in 31 studies

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
" Specific prenatal exposures were identified at different times in the first trimester of pregnancy: crack cocaine, marijuana, disulfiram, heavy ethanol exposure, and cigarettes."4.79Prenatal exposure to disulfiram implicated in the cause of malformations in discordant monozygotic twins. ( Aylsworth, AS; Callanan, NP; Farber, RA; Reitnauer, PJ, 1997)
"Disulfiram has been used effectively to deter alcohol consumption in patients with a history of alcohol abuse."3.68First trimester disulfiram exposure: report of two cases. ( Helmbrecht, GD; Hoskins, IA, 1993)
"Disulfiram, in 1 mg and 10 mg oral doses, was given to inbred C3H mice prior to and for the duration of pregnancy."3.67The effects of disulfiram on the experimental C3H mouse embryo. ( Folb, PI; Thompson, PA, 1985)
"We report the case of a severely malformed and retarded girl whose previously alcoholic mother had taken disulfiram early during the pregnancy, but denied having taken alcohol."3.66A malformed child whose previously alcoholic mother had taken disulfiram. ( Clarkson, JE; Gardner, RJ, 1981)
"Disulfiram is a dehydrogenase inhibitor used to treat alcoholism and has been suggested as a proteasome inhibitor."1.48Disulfiram inhibits placental soluble FMS-like tyrosine kinase-1 and soluble endoglin secretion independent of the proteasome. ( Brownfoot, FC; Cannon, P; Hannan, NJ; Hastie, R; Kaitu'u-Lino, TJ; Nguyen, V; Tong, S; Ye, L, 2018)

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-199022 (70.97)18.7374
1990's6 (19.35)18.2507
2000's1 (3.23)29.6817
2010's1 (3.23)24.3611
2020's1 (3.23)2.80

Authors

AuthorsStudies
Kelty, E1
Terplan, M1
Greenland, M1
Preen, D1
Hastie, R1
Ye, L1
Hannan, NJ1
Brownfoot, FC1
Cannon, P1
Nguyen, V1
Tong, S1
Kaitu'u-Lino, TJ1
Kido, R1
Sato, I1
Tsuda, S1
Jasim, S1
Tjälve, H1
Danielsson, BR3
Chan, AW1
Dehaene, P1
Titran, M1
Dubois, D1
Oskarsson, A5
Dencker, L2
Slawson, M1
Slawson, S1
Gardner, RJ1
Clarkson, JE1
Véghelyi, P1
Leisztner, L1
Osztovics, M1
Korányi, G1
Kardos, G1
Ullrich, E1
Helmbrecht, GD1
Hoskins, IA1
Reitnauer, PJ1
Callanan, NP1
Farber, RA1
Aylsworth, AS1
Xavier-Neto, J1
Neville, CM1
Shapiro, MD1
Houghton, L1
Wang, GF1
Nikovits, W1
Stockdale, FE1
Rosenthal, N1
Nora, AH1
Nora, JJ1
Blu, J1
Barry, H1
Hamon, B1
Soyez, C1
Jonville, AP1
Autret, E1
Luthman, J1
Olson, L1
Björklund, H1
Henschen, A1
Hoffer, B1
Khayat, A1
Rao, AR1
Hussain, SP1
Jannu, L1
Johansson, A1
Santos, Rde O1
Guaraldo, AM1
Passos, LA1
Gilioli, R1
Rangel, Hde A1
Thompson, PA1
Folb, PI1
O'Reilly, RA1
Salgo, MP1
Oster, G1
Fujii, T1
Kato, J1
Robens, JF1
Favre-Tissort, M1
Delatour, P1

Reviews

5 reviews available for disulfiram and Pregnancy

ArticleYear
Pharmacotherapies for the Treatment of Alcohol Use Disorders During Pregnancy: Time to Reconsider?
    Drugs, 2021, Volume: 81, Issue:7

    Topics: Acamprosate; Alcohol Abstinence; Alcohol Deterrents; Alcoholism; Animals; Comorbidity; Disulfiram; F

2021
Effects of combined alcohol and benzodiazepine: a review.
    Drug and alcohol dependence, 1984, Volume: 13, Issue:4

    Topics: Abnormalities, Drug-Induced; Accidents, Traffic; Adolescent; Adult; Age Factors; Alcohol Drinking; A

1984
Prenatal exposure to disulfiram implicated in the cause of malformations in discordant monozygotic twins.
    Teratology, 1997, Volume: 56, Issue:6

    Topics: Abnormalities, Drug-Induced; Adult; Alcohol Deterrents; Alcohol Drinking; Cleft Palate; Disulfiram;

1997
Treating scabies.
    Drug and therapeutics bulletin, 1988, Mar-07, Volume: 26, Issue:5

    Topics: Benzoates; Disulfiram; Female; Hexachlorocyclohexane; Humans; Malathion; Pregnancy; Scabies

1988
Hazards of anticoagulant treatment: other drugs, other diseases.
    Thrombosis et diathesis haemorrhagica. Supplementum, 1973, Volume: 56

    Topics: Administration, Oral; Animals; Anticoagulants; Barbiturates; Biological Transport; Blood Coagulation

1973

Other Studies

26 other studies available for disulfiram and Pregnancy

ArticleYear
Disulfiram inhibits placental soluble FMS-like tyrosine kinase-1 and soluble endoglin secretion independent of the proteasome.
    Pregnancy hypertension, 2018, Volume: 14

    Topics: Acetaldehyde Dehydrogenase Inhibitors; Disulfiram; Endoglin; Enzyme-Linked Immunosorbent Assay; Fema

2018
Detection of in vivo DNA damage induced by ethanol in multiple organs of pregnant mice using the alkaline single cell gel electrophoresis (Comet) assay.
    The Journal of veterinary medical science, 2006, Volume: 68, Issue:1

    Topics: Acetaldehyde; Analysis of Variance; Animals; Comet Assay; Disulfiram; DNA Damage; Dose-Response Rela

2006
Effect of thiuram sulphides on the uptake and distribution of nickel in pregnant and non-pregnant mice.
    Toxicology, 1984, Sep-28, Volume: 32, Issue:4

    Topics: Administration, Oral; Animals; Autoradiography; Disulfiram; Ditiocarb; Female; Fetus; Maternal-Fetal

1984
Placental transfer and fetal distribution of cadmium and mercury after treatment with dithiocarbamates.
    Archives of toxicology, 1984, Volume: 55, Issue:3

    Topics: Animals; Autoradiography; Cadmium; Disulfiram; Ditiocarb; Female; Fetus; Maternal-Fetal Exchange; Me

1984
[Pierre Robin syndrome and heart malformations in a newborn infant. The role of disulfiram during pregnancy?].
    Presse medicale (Paris, France : 1983), 1984, May-26, Volume: 13, Issue:22

    Topics: Adult; Disulfiram; Female; Heart Defects, Congenital; Humans; Infant, Newborn; Pierre Robin Syndrome

1984
Placental transfer and fetal distribution of lead in mice after treatment with dithiocarbamates.
    Archives of toxicology, 1984, Volume: 55, Issue:1

    Topics: Animals; Disulfiram; Ditiocarb; Female; Fetus; Lead; Maternal-Fetal Exchange; Mice; Mice, Inbred C57

1984
When alcohol is contraindicated don't forget the 'hidden' alcohol in drugs.
    RN, 1983, Volume: 46, Issue:4

    Topics: Adult; Alcoholism; Child; Disulfiram; Ethanol; Female; Humans; Male; Pharmaceutical Preparations; Pr

1983
A malformed child whose previously alcoholic mother had taken disulfiram.
    The New Zealand medical journal, 1981, Mar-25, Volume: 93, Issue:680

    Topics: Abnormalities, Drug-Induced; Child; Child, Preschool; Disulfiram; Female; Fetal Alcohol Spectrum Dis

1981
[Development of the fetal alcohol syndrome].
    Orvosi hetilap, 1980, Jan-20, Volume: 121, Issue:3

    Topics: Acetaldehyde; Alcoholism; Disulfiram; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Humans; Inf

1980
First trimester disulfiram exposure: report of two cases.
    American journal of perinatology, 1993, Volume: 10, Issue:1

    Topics: Abnormalities, Drug-Induced; Adult; Alcoholism; Disulfiram; Female; Fetus; Humans; Infant, Newborn;

1993
A retinoic acid-inducible transgenic marker of sino-atrial development in the mouse heart.
    Development (Cambridge, England), 1999, Volume: 126, Issue:12

    Topics: Alkaline Phosphatase; Animals; Disulfiram; Enzyme Inhibitors; Female; Gene Expression Regulation, De

1999
Limb-reduction anomalies in infants born to disulfiram-treated alcoholic mothers.
    Lancet (London, England), 1977, Sep-24, Volume: 2, Issue:8039

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Alcoholism; Disulfiram; Ectromelia; Female; Hu

1977
Contribution to understanding and treating alcoholics.
    Annals of the New York Academy of Sciences, 1976, Volume: 273

    Topics: Adult; Aggression; Alcoholism; Behavior; Child; Disulfiram; Female; Humans; Male; Marriage; Methods;

1976
[Pregnancy in patients treated with disulfiram].
    Presse medicale (Paris, France : 1983), 1991, Jun-15, Volume: 20, Issue:23

    Topics: Abortion, Therapeutic; Adult; Disulfiram; Female; Humans; Pregnancy

1991
Combined lead acetate and disulfiram treatment-induced alterations of glial fibrillary acidic protein (GFA) immunoreactive astrocytes in brain smears.
    Toxicology, 1991, Volume: 65, Issue:3

    Topics: Animals; Animals, Suckling; Astrocytes; Body Weight; Cerebellar Cortex; Disulfiram; Drug Interaction

1991
Foetal and maternal distribution of inhaled mercury vapour in pregnant mice: influence of selenite and dithiocarbamates.
    Pharmacology & toxicology, 1990, Volume: 67, Issue:3

    Topics: Administration, Inhalation; Animals; Disulfiram; Ditiocarb; Female; Fetus; Maternal-Fetal Exchange;

1990
Modulation of 7,12-dimethylbenz[a]anthracene-induced transmammary carcinogenesis by disulfiram and butylated hydroxyanisole in mice.
    Japanese journal of cancer research : Gann, 1989, Volume: 80, Issue:12

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Butylated Hydroxyanisole; Disulfiram; Female; Lactation;

1989
Effects of perinatal treatment with lead and disulfiram on ALAD activity in blood, liver and kidney and urinary ALA excretion in rats.
    Pharmacology & toxicology, 1989, Volume: 64, Issue:4

    Topics: Aminolevulinic Acid; Animals; Body Weight; Disulfiram; Drinking; Female; Hematocrit; Kidney; Lead; L

1989
Lead-induced inclusion bodies in rat kidney after perinatal treatment with lead and disulfiram.
    Toxicology, 1987, Volume: 44, Issue:1

    Topics: Animals; Chelating Agents; Disulfiram; Female; Inclusion Bodies; Kidney; Kidney Tubules, Proximal; L

1987
[Use of tetraethylthiuram monosulfide in the treatment of ectoparasites in mice].
    Revista de saude publica, 1988, Volume: 22, Issue:1

    Topics: Animals; Animals, Laboratory; Disulfiram; Female; Male; Mice; Mice, Inbred BALB C; Mice, Inbred CBA;

1988
Effect of disulfiram on milk transfer and tissue distribution of lead in the neonatal rat.
    Toxicology letters, 1987, Volume: 36, Issue:1

    Topics: Animals; Animals, Newborn; Disulfiram; Female; Lead Poisoning; Milk; Pregnancy; Rats; Rats, Inbred S

1987
The effects of disulfiram on the experimental C3H mouse embryo.
    Journal of applied toxicology : JAT, 1985, Volume: 5, Issue:1

    Topics: Abnormalities, Drug-Induced; Acetaldehyde; Animals; Disulfiram; DNA; Embryo, Mammalian; Female; Fetu

1985
Fetal resorption induced by disulfiram in rats.
    Journal of reproduction and fertility, 1974, Volume: 39, Issue:2

    Topics: Abortifacient Agents; Administration, Oral; Animals; Disulfiram; Embryo Implantation; Female; Pregna

1974
Proceedings: Effects of L-DOPA, disulfiram and haloperidol on reappearance of cyclicity in androgen-sterilized rats (ASR).
    Japanese journal of pharmacology, 1974, Volume: 24, Issue:0

    Topics: Androgens; Animals; Dihydroxyphenylalanine; Disulfiram; Estrus; Female; Haloperidol; Infertility, Fe

1974
Teratologic studies of carbaryl, diazinon, norea, disulfiram, and thiram in small laboratory animals.
    Toxicology and applied pharmacology, 1969, Volume: 15

    Topics: Abnormalities, Drug-Induced; Animals; Anti-Infective Agents, Local; Bone and Bones; Carbamates; Cric

1969
[Psychopharmacology and teratogenesis a propos of disulfiram: experimental trial].
    Annales medico-psychologiques, 1965, Volume: 123, Issue:5

    Topics: Abnormalities, Drug-Induced; Adult; Animals; Clubfoot; Disulfiram; Female; Humans; In Vitro Techniqu

1965