Compounds > disulfiram
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disulfiram and Peripheral Nervous System Diseases

disulfiram has been researched along with Peripheral Nervous System Diseases in 42 studies

Peripheral Nervous System Diseases: Diseases of the peripheral nerves external to the brain and spinal cord, which includes diseases of the nerve roots, ganglia, plexi, autonomic nerves, sensory nerves, and motor nerves.

Research Excerpts

ExcerptRelevanceReference
"Disulfiram is an alcohol-deterring agent with few rare serious adverse effects, usually dose-related, reversible, and more frequent with comorbid alcohol and nicotine dependence."6.49Disulfiram-induced combined irreversible anterior ischemic optic neuropathy and reversible peripheral neuropathy: a prospective case report and review of the literature. ( Bairy, BK; Kulkarni, RR; Pradeep, AV, 2013)
"Disulfiram is used in the treatment of chronic alcoholism, because of the unpleasant symptoms produced after ethanol intake."3.78[Disulfiram-induced polyneurophaty]. ( Apostolski, S; Knezević-Apostolski, S; Petković, S; Radulović, L; Vujisić, S; Vukmirović, F, 2012)
"Disulfiram is widely used for aversive treatment of alcoholism."3.71[Disulfiram neuropathy. Report of 3 cases]. ( Bevilacqua, JA; Díaz, M; Díaz, V; Fruns, M; Silva, C, 2002)
"Peripheral neuropathy and optic neuritis occurring in alcoholics are sometimes due to the toxic effects of disulfiram rather than to alcohol."3.65Peripheral neuropathy after disulfiram administration. ( Benjamin, S; Gardner-Thorpe, C, 1971)
"Disulfiram is an alcohol-deterring agent with few rare serious adverse effects, usually dose-related, reversible, and more frequent with comorbid alcohol and nicotine dependence."2.49Disulfiram-induced combined irreversible anterior ischemic optic neuropathy and reversible peripheral neuropathy: a prospective case report and review of the literature. ( Bairy, BK; Kulkarni, RR; Pradeep, AV, 2013)
"Disulfiram may cause a peripheral neuropathy that is considered dose- and duration-of-exposure-related."1.35Disulfiram neuropathy: two cases of distal axonopathy. ( Broglio, L; Buzio, S; Choub, A; Cotelli, MS; Filosto, M; Lazzarini, C; Mancuso, M; Padovani, A; Pasolini, MP; Scarpelli, M; Tentorio, M, 2008)
"To report a case of optic and peripheral neuropathy after chronic use of disulfiram for alcohol dependence management."1.34Disulfiram-induced transient optic and peripheral neuropathy: a case report. ( Beatty, S; Guerin, M; Orakzai, A, 2007)
"Disulfirame is a rare cause of peripheral neuropathy in subjects with chronic alcoholism."1.29[Peripheral neuropathies caused by disulfiram]. ( Bregigeon, M; Brosset, C; Dano, P; Tammam, D, 1996)
"As disulfiram treatment may cause severe side effects it is recommended that the lowest possible dosage by employed."1.28[Disulfiram neuropathy]. ( Klugkist, H; Preuss, S, 1992)
"Disulfiram toxicity is a well-recognized cause of peripheral neuropathy and encephalopathy, usually developing within a few months of the start of therapy."1.27Reversible, late-onset disulfiram-induced neuropathy and encephalopathy. ( Ashby, P; Bilbao, J; Borrett, D; Carlen, P, 1985)
" Later on, a temporary increase in disulfiram dosage to 1."1.26[Disulfiram-induced peripheral neuropathies (author's transl)]. ( Ecoffet, M; Graveleau, J; Villard, A, 1980)

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-199028 (66.67)18.7374
1990's4 (9.52)18.2507
2000's4 (9.52)29.6817
2010's5 (11.90)24.3611
2020's1 (2.38)2.80

Authors

AuthorsStudies
Baraldi, PG1
Preti, D1
Materazzi, S1
Geppetti, P1
Coronel, SI1
Dorman, J1
Kulkarni, RR1
Pradeep, AV1
Bairy, BK1
Tran, AT1
Rison, RA1
Beydoun, SR1
Karamanakos, PN2
Panteli, ES1
Pappas, P1
Marselos, M1
Vujisić, S1
Radulović, L1
Knezević-Apostolski, S1
Petković, S1
Vukmirović, F1
Apostolski, S1
Bevilacqua, JA1
Díaz, M1
Díaz, V1
Silva, C1
Fruns, M1
Orakzai, A1
Guerin, M1
Beatty, S1
Filosto, M1
Tentorio, M1
Broglio, L1
Buzio, S1
Lazzarini, C1
Pasolini, MP1
Cotelli, MS1
Scarpelli, M1
Mancuso, M1
Choub, A1
Padovani, A1
Bilbao, JM3
Briggs, SJ1
Gray, TA1
Graveleau, J2
Ecoffet, M1
Villard, A1
Strandjord, RE1
Haanshuus, AG1
Morcamp, D2
Boudin, G1
Mizon, JP2
Mokri, B1
Ohnishi, A1
Dyck, PJ1
Nukada, H1
Pollock, M1
Marra, TR1
Watson, CP1
Ashby, P3
Ansbacher, LE1
Bosch, EP1
Cancilla, PA1
Lemperiere, T1
Ades, J1
Hardy, P1
van Rossum, J1
Roos, RA1
Bots, GT1
De Sèze, J1
Caparros-Lefebvre, D1
Nkenjuo, JB1
Hurtevent, JF1
Petit, H1
Dano, P1
Tammam, D1
Brosset, C1
Bregigeon, M1
Froissart, M1
Gentit, M1
Moddel, G1
Payne, D1
Norris, FH1
Zuccarello, M1
Anzil, AP1
Klugkist, H1
Preuss, S1
Palliyath, SK1
Schwartz, BD1
Gant, L1
Frisoni, GB1
Di Monda, V1
Bergouignan, FX1
Vital, C1
Henry, P1
Eschapasse, P1
Hassard, GH1
Landgraf, CW1
Borrett, D1
Bilbao, J1
Carlen, P1
Bartle, WR1
Fisher, MM1
Kerenyi, N1
Dalessio, DJ1
Kane, FJ1
Gardner-Thorpe, C1
Benjamin, S1
Leibold, JE1
Kirk, L1
Cavanagh, JB1

Reviews

5 reviews available for disulfiram and Peripheral Nervous System Diseases

ArticleYear
Transient receptor potential ankyrin 1 (TRPA1) channel as emerging target for novel analgesics and anti-inflammatory agents.
    Journal of medicinal chemistry, 2010, Jul-22, Volume: 53, Issue:14

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Asthma; Humans; Ion Channel Gating; Neurons; Pain; Pe

2010
Disulfiram-induced combined irreversible anterior ischemic optic neuropathy and reversible peripheral neuropathy: a prospective case report and review of the literature.
    The Journal of neuropsychiatry and clinical neurosciences, 2013,Fall, Volume: 25, Issue:4

    Topics: Adult; Disulfiram; Humans; Male; Optic Neuropathy, Ischemic; Peripheral Nervous System Diseases; Pro

2013
Disulfiram neuropathy: a review (1971-1988) and report of a case.
    Alcohol and alcoholism (Oxford, Oxfordshire), 1989, Volume: 24, Issue:5

    Topics: Adult; Disulfiram; Gait; Humans; Leg; Male; Movement Disorders; Peripheral Nervous System Diseases;

1989
Drugs having a toxic effect on the optic nerve.
    International ophthalmology clinics, 1971, Volume: 11, Issue:2

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Anti-Infective Agents; Contraceptives, Oral; Digitalis G

1971
Peripheral neuropathy caused by chemical agents.
    CRC critical reviews in toxicology, 1973, Volume: 2, Issue:3

    Topics: Acrylamides; Animals; Arsenic; Axons; Carbon Disulfide; Disulfiram; Humans; In Vitro Techniques; Iso

1973

Other Studies

37 other studies available for disulfiram and Peripheral Nervous System Diseases

ArticleYear
Use of Neuromuscular Ultrasound in the Diagnosis of Disulfiram Polyneuropathy.
    Journal of clinical neuromuscular disease, 2022, Jun-01, Volume: 23, Issue:4

    Topics: Adult; Alcoholism; Disulfiram; Female; Humans; Peripheral Nervous System Diseases; Polyneuropathies;

2022
Disulfiram neuropathy: two case reports.
    Journal of medical case reports, 2016, Mar-31, Volume: 10

    Topics: Adult; Alcohol Deterrents; Alcoholism; Disulfiram; Female; Humans; Hypesthesia; Middle Aged; Neuralg

2016
Comment on: Sensory-motor axonal polyneuropathy involving cranial nerves: An uncommon manifestation of disulfiram toxicity (Santos et al., Clin Neurol Neurosurg, 152:12-15, 2016).
    Clinical neurology and neurosurgery, 2017, Volume: 154

    Topics: Cranial Nerves; Disulfiram; Humans; Peripheral Nervous System Diseases; Polyneuropathies

2017
Disulfiram neuropathy: two cases of distal axonopathy.
    Clinical toxicology (Philadelphia, Pa.), 2008, Volume: 46, Issue:9

    Topics: Alcohol Deterrents; Animals; Axons; Disulfiram; Dopamine beta-Hydroxylase; Dose-Response Relationshi

2008
[Disulfiram-induced polyneurophaty].
    Vojnosanitetski pregled, 2012, Volume: 69, Issue:5

    Topics: Alcohol Deterrents; Alcoholism; Disulfiram; Humans; Male; Peripheral Nervous System Diseases; Young

2012
[Disulfiram neuropathy. Report of 3 cases].
    Revista medica de Chile, 2002, Volume: 130, Issue:9

    Topics: Adult; Alcohol Deterrents; Alcoholism; Disulfiram; Humans; Male; Middle Aged; Peripheral Nervous Sys

2002
Disulfiram-induced transient optic and peripheral neuropathy: a case report.
    Irish journal of medical science, 2007, Volume: 176, Issue:4

    Topics: Alcoholism; Disulfiram; Follow-Up Studies; Humans; Male; Middle Aged; Optic Nerve Diseases; Peripher

2007
Disulfiram neuropathy: two cases of distal axonopathy.
    Clinical toxicology (Philadelphia, Pa.), 2008, Volume: 46, Issue:4

    Topics: Adult; Alcohol Deterrents; Axons; Disulfiram; Female; Humans; Male; Peripheral Nerves; Peripheral Ne

2008
Filamentous axonopathy in disulfiram neuropathy.
    Ultrastructural pathology, 1984, Volume: 7, Issue:4

    Topics: Alcoholism; Axons; Disulfiram; Female; Humans; Middle Aged; Peripheral Nervous System Diseases; Spin

1984
[Disulfiram-induced peripheral neuropathies (author's transl)].
    La Nouvelle presse medicale, 1980, Oct-25, Volume: 9, Issue:39

    Topics: Adult; Disulfiram; Female; Humans; Peripheral Nervous System Diseases

1980
[Polyneuropathy induced by disulfiram].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1980, Oct-20, Volume: 100, Issue:29

    Topics: Adult; Disulfiram; Humans; Male; Peripheral Nervous System Diseases

1980
[Unusual neurologic complications of disulfiram].
    La Nouvelle presse medicale, 1981, Feb-07, Volume: 10, Issue:5

    Topics: Adult; Disulfiram; Humans; Papilledema; Peripheral Nervous System Diseases

1981
Disulfiram neuropathy.
    Neurology, 1981, Volume: 31, Issue:6

    Topics: Adult; Alcoholism; Carbon Disulfide; Disulfiram; Female; Humans; Male; Mathematics; Middle Aged; Mye

1981
Disulfiram neuropathy. A morphometric study of sural nerve.
    Journal of the neurological sciences, 1981, Volume: 51, Issue:1

    Topics: Adult; Chloral Hydrate; Disulfiram; Female; Humans; Male; Middle Aged; Nerve Fibers; Peripheral Nerv

1981
Disulfiram neuropathy.
    Wisconsin medical journal, 1981, Volume: 80, Issue:5

    Topics: Adult; Alcoholism; Disulfiram; Humans; Male; Peripheral Nervous System Diseases

1981
Disulfiram neuropathy.
    Canadian Medical Association journal, 1980, Jul-19, Volume: 123, Issue:2

    Topics: Adult; Disulfiram; Female; Humans; Male; Middle Aged; Peripheral Nerves; Peripheral Nervous System D

1980
Disulfiram neuropathy: a neurofilamentous distal axonopathy.
    Neurology, 1982, Volume: 32, Issue:4

    Topics: Action Potentials; Adult; Axons; Cytoskeleton; Disulfiram; Female; Humans; Microscopy, Electron; Ner

1982
[Neuropsychic complications of disulfiram therapy. Apropos of a case].
    Annales medico-psychologiques, 1982, Volume: 140, Issue:1

    Topics: Disulfiram; Female; Humans; Middle Aged; Peripheral Nervous System Diseases; Substance-Related Disor

1982
Disulfiram polyneuropathy.
    Clinical neurology and neurosurgery, 1984, Volume: 86, Issue:2

    Topics: Adult; Carbon Disulfide; Disulfiram; Dose-Response Relationship, Drug; Female; Humans; Male; Middle

1984
[Acute and reversible myoclonic encephalopathy, extrapyramidal syndrome, polyneuropathy caused by chronic disulfiram poisoning].
    Revue neurologique, 1995, Volume: 151, Issue:11

    Topics: Acute Disease; Adult; Alcohol Deterrents; Basal Ganglia Diseases; Chronic Disease; Disulfiram; Femal

1995
[Peripheral neuropathies caused by disulfiram].
    Revue neurologique, 1996, Volume: 152, Issue:4

    Topics: Adult; Alcohol Deterrents; Disulfiram; Dose-Response Relationship, Drug; Humans; Male; Peripheral Ne

1996
[Peripheral neurologic manifestations in conjunction with prolonged use of disulfiram].
    Lille medical : journal de la Faculte de medecine et de pharmacie de l'Universite de Lille, 1977, Volume: 22, Issue:10

    Topics: Adult; Disulfiram; Humans; Male; Peripheral Nervous System Diseases

1977
Disulfiram neuropathy.
    Archives of neurology, 1978, Volume: 35, Issue:10

    Topics: Adult; Disulfiram; Humans; Male; Peripheral Nervous System Diseases; Sural Nerve

1978
Neuropathy associated with disulfiram administration.
    Archives of neurology, 1979, Volume: 36, Issue:6

    Topics: Adult; Disulfiram; Female; Humans; Male; Paralysis; Peripheral Nervous System Diseases; Peroneal Ner

1979
A localized model of experimental neuropathy by topical application of disulfiram.
    Experimental neurology, 1979, Volume: 64, Issue:3

    Topics: Animals; Disease Models, Animal; Disulfiram; Male; Peripheral Nervous System Diseases; Rats; Sciatic

1979
[Disulfiram neuropathy].
    Deutsche medizinische Wochenschrift (1946), 1992, Aug-21, Volume: 117, Issue:34

    Topics: Adult; Alcoholism; Axons; Disulfiram; Electromyography; Electrophysiology; Female; Humans; Male; Par

1992
Peripheral nerve functions in chronic alcoholic patients on disulfiram: a six month follow up.
    Journal of neurology, neurosurgery, and psychiatry, 1990, Volume: 53, Issue:3

    Topics: Alcoholism; Disulfiram; Electromyography; Humans; Median Nerve; Motor Neurons; Muscles; Neural Condu

1990
Disulfiram neuropathy.
    Journal of neurology, 1988, Volume: 235, Issue:6

    Topics: Alcoholism; Disulfiram; Humans; Male; Microscopy, Electron; Middle Aged; Motor Neurons; Neurons, Aff

1988
Peripheral neuropathy from disulfiram (Antabuse) therapy.
    South Dakota journal of medicine, 1988, Volume: 41, Issue:10

    Topics: Alcoholism; Disulfiram; Drug Interactions; Humans; Male; Peripheral Nervous System Diseases

1988
Reversible, late-onset disulfiram-induced neuropathy and encephalopathy.
    Annals of neurology, 1985, Volume: 17, Issue:4

    Topics: Aged; Biopsy; Brain Diseases; Disulfiram; Humans; Male; Peripheral Nervous System Diseases; Sural Ne

1985
Disulfiram-induced hepatitis. Report of two cases and review of the literature.
    Digestive diseases and sciences, 1985, Volume: 30, Issue:9

    Topics: Adult; Alcoholism; Alkaline Phosphatase; Chemical and Drug Induced Liver Injury; Cyanamide; Disulfir

1985
Peripheral neuropathy and disulfiram.
    Lancet (London, England), 1971, Sep-18, Volume: 2, Issue:7725

    Topics: Alcoholism; Disulfiram; Humans; Neural Conduction; Peripheral Nervous System Diseases

1971
Peripheral neuropathy associated with disulfiram (Antabuse) therapy.
    Bulletin of the Los Angeles neurological societies, 1968, Volume: 33, Issue:3

    Topics: Alcoholism; Disulfiram; Female; Humans; Male; Middle Aged; Peripheral Nervous System Diseases

1968
Carbon disulfide intoxication from overdosage of disulfiram.
    The American journal of psychiatry, 1970, Volume: 127, Issue:5

    Topics: Adult; Brain Injuries; Carbon Disulfide; Chlordiazepoxide; Depression; Disulfiram; Electroencephalog

1970
Peripheral neuropathy after disulfiram administration.
    Journal of neurology, neurosurgery, and psychiatry, 1971, Volume: 34, Issue:3

    Topics: Adult; Alcoholism; Brain; Disulfiram; Female; Humans; Male; Middle Aged; Optic Neuritis; Peripheral

1971
[Peripheral neuropathies caused by disulfiram (antabuse)].
    Revue neurologique, 1972, Volume: 126, Issue:2

    Topics: Alcoholic Intoxication; Deglutition Disorders; Disulfiram; Ethanol; Facial Paralysis; Female; Humans

1972
[Should we contnue to use disulfiram (Antabus)].
    Ugeskrift for laeger, 1973, Jul-09, Volume: 135, Issue:28

    Topics: Alcoholism; Disulfiram; Humans; Optic Neuritis; Peripheral Nervous System Diseases; Scotoma

1973