disulfiram has been researched along with Pemphigoid, Benign Mucous Membrane in 2 studies
Pemphigoid, Benign Mucous Membrane: A chronic blistering disease with predilection for mucous membranes and less frequently the skin, and with a tendency to scarring. It is sometimes called ocular pemphigoid because of conjunctival mucous membrane involvement.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mechanisms underlying scarring are largely unknown in MMP and effective treatment options are limited." | 1.62 | Increased Fibrosis in a Mouse Model of Anti-Laminin 332 Mucous Membrane Pemphigoid Remains Unaltered by Inhibition of Aldehyde Dehydrogenase. ( Boch, K; Brinckmann, J; Busch, H; Chakievska, L; Diel, L; Fähnrich, A; Künzel, S; Patzelt, S; Pigors, M; Schmidt, E; Steenbock, H, 2021) |
| "These data suggest that progressive scarring in OMMP results from ALDH/RA fibroblast autoregulation, that the ALDH1 subfamily has a central role in immune-mediated ocular mucosal scarring, and that ALDH inhibition with disulfiram is a potential and readily translatable antifibrotic therapy." | 1.43 | Aldehyde dehydrogenase inhibition blocks mucosal fibrosis in human and mouse ocular scarring. ( Abraham, DJ; Ahadome, SD; Calder, VL; Daniels, JT; Dart, JK; Norman, JT; Ponticos, M; Rayapureddi, S; Saban, DR; Saw, VP, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Patzelt, S | 1 |
| Pigors, M | 1 |
| Steenbock, H | 1 |
| Diel, L | 1 |
| Boch, K | 1 |
| Chakievska, L | 1 |
| Künzel, S | 1 |
| Busch, H | 1 |
| Fähnrich, A | 1 |
| Brinckmann, J | 1 |
| Schmidt, E | 1 |
| Ahadome, SD | 1 |
| Abraham, DJ | 1 |
| Rayapureddi, S | 1 |
| Saw, VP | 1 |
| Saban, DR | 1 |
| Calder, VL | 1 |
| Norman, JT | 1 |
| Ponticos, M | 1 |
| Daniels, JT | 1 |
| Dart, JK | 1 |
2 other studies available for disulfiram and Pemphigoid, Benign Mucous Membrane
| Article | Year |
|---|---|
Increased Fibrosis in a Mouse Model of Anti-Laminin 332 Mucous Membrane Pemphigoid Remains Unaltered by Inhibition of Aldehyde Dehydrogenase.
Topics: Aldehyde Dehydrogenase; Animals; Autoimmune Diseases; Cicatrix; Collagen; Disease Models, Animal; Di | 2021 |
Aldehyde dehydrogenase inhibition blocks mucosal fibrosis in human and mouse ocular scarring.
Topics: Adult; Aged; Aged, 80 and over; Aldehyde Dehydrogenase; Animals; Cells, Cultured; Cicatrix; Conjunct | 2016 |