disulfiram has been researched along with Ovarian Neoplasms in 7 studies
Ovarian Neoplasms: Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Among gynecological cancers, ovarian cancer has a high mortality rate." | 1.91 | Proteomics Analysis Revealed Smad3 as a Potential Target of the Synergistic Antitumor Activity of Disulfiram and Cisplatin in Ovarian Cancer. ( Deng, Q; Ding, C; Du, R; Hong, B; Li, K; Nie, J; Qi, J; Sun, F; Sun, Q; Wang, H; Wang, W; Zhong, W, 2023) |
| " A synergistic treatment with drug supporting activity could maximize the cytotoxic effects of chemotherapeutic agents on tumor cells while decreasing the dosage of each drug to potentially reduce toxicity." | 1.72 | Blockade of ALDH in Cisplatin-Resistant Ovarian Cancer Stem Cells In Vitro Synergistically Enhances Chemotherapy-Induced Cell Death. ( Guo, F; Kaufmann, AM; Sehouli, J; Yang, Z, 2022) |
| "Disulfiram (DSF) is a drug used for treatment of alcoholism that has also displayed promising anti-cancer activity." | 1.51 | Inhibitory effect on ovarian cancer ALDH+ stem-like cells by Disulfiram and Copper treatment through ALDH and ROS modulation. ( Albers, AE; Guo, F; Kaufmann, AM; Kulbe, H; Sehouli, J; Yang, Z, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 4 (57.14) | 2.80 |
| Authors | Studies |
|---|---|
| Guo, F | 2 |
| Yang, Z | 2 |
| Sehouli, J | 2 |
| Kaufmann, AM | 2 |
| Du, R | 1 |
| Sun, F | 1 |
| Li, K | 1 |
| Qi, J | 1 |
| Zhong, W | 1 |
| Wang, W | 1 |
| Sun, Q | 1 |
| Deng, Q | 1 |
| Wang, H | 1 |
| Nie, J | 1 |
| Ding, C | 1 |
| Hong, B | 1 |
| Gan, Y | 1 |
| Liu, T | 1 |
| Feng, W | 1 |
| Wang, L | 1 |
| Li, LI | 1 |
| Ning, Y | 1 |
| Kulbe, H | 1 |
| Albers, AE | 1 |
| Torralba, M | 1 |
| Farra, R | 1 |
| Maddaloni, M | 1 |
| Grassi, M | 1 |
| Dapas, B | 1 |
| Grassi, G | 1 |
| Jiao, Y | 1 |
| Hannafon, BN | 1 |
| Zhang, RR | 1 |
| Fung, KM | 1 |
| Ding, WQ | 1 |
| O'Brien, A | 1 |
| Barber, JE | 1 |
| Reid, S | 1 |
| Niknejad, N | 1 |
| Dimitroulakos, J | 1 |
7 other studies available for disulfiram and Ovarian Neoplasms
| Article | Year |
|---|---|
Blockade of ALDH in Cisplatin-Resistant Ovarian Cancer Stem Cells In Vitro Synergistically Enhances Chemotherapy-Induced Cell Death.
Topics: Antineoplastic Agents; Apoptosis; Cisplatin; Disulfiram; Female; Humans; Necrosis; Neoplastic Stem C | 2022 |
Proteomics Analysis Revealed Smad3 as a Potential Target of the Synergistic Antitumor Activity of Disulfiram and Cisplatin in Ovarian Cancer.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cisplatin; Disulfir | 2023 |
Drug repositioning of disulfiram induces endometrioid epithelial ovarian cancer cell death via the both apoptosis and cuproptosis pathways.
Topics: Animals; Apoptosis; Carcinoma, Ovarian Epithelial; Cell Death; Copper; Disulfiram; Drug Repositionin | 2023 |
Inhibitory effect on ovarian cancer ALDH+ stem-like cells by Disulfiram and Copper treatment through ALDH and ROS modulation.
Topics: Aldehyde Dehydrogenase; Apoptosis; Cell Cycle; Cell Line, Tumor; Cisplatin; Copper; Disulfiram; Fema | 2019 |
Drugs Repurposing in High-Grade Serous Ovarian Cancer.
Topics: Antineoplastic Agents; Disulfiram; Drug Repositioning; Female; Humans; Ovarian Neoplasms; Pharmaceut | 2020 |
Docosahexaenoic acid and disulfiram act in concert to kill cancer cells: a mutual enhancement of their anticancer actions.
Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Proliferation; Cell Survival; Disulfiram; D | 2017 |
Enhancement of cisplatin cytotoxicity by disulfiram involves activating transcription factor 3.
Topics: Activating Transcription Factor 3; Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; C | 2012 |