disulfiram has been researched along with Osteosarcoma in 4 studies
Osteosarcoma: A sarcoma originating in bone-forming cells, affecting the ends of long bones. It is the most common and most malignant of sarcomas of the bones, and occurs chiefly among 10- to 25-year-old youths. (From Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this study, we reported the effects of disulfiram, a clinically used anti-alcoholism drug, on tumor invasion suppression, as well as its effects on the activity of MMP-2 and MMP-9 in human osteosarcoma cells (U2OS)." | 7.74 | Disulfiram suppresses invasive ability of osteosarcoma cells via the inhibition of MMP-2 and MMP-9 expression. ( Chang, YC; Cho, HJ; Cho, YS; Choe, JY; Choi, MR; Han, SM; Lee, KG; Lee, TS; Lee, YS; Moon, YS; Park, JB; Park, KK; Park, NG; Park, YY; Sin, DI; Yeo, JH, 2007) |
| " In this study, we reported the effects of disulfiram, a clinically used anti-alcoholism drug, on tumor invasion suppression, as well as its effects on the activity of MMP-2 and MMP-9 in human osteosarcoma cells (U2OS)." | 3.74 | Disulfiram suppresses invasive ability of osteosarcoma cells via the inhibition of MMP-2 and MMP-9 expression. ( Chang, YC; Cho, HJ; Cho, YS; Choe, JY; Choi, MR; Han, SM; Lee, KG; Lee, TS; Lee, YS; Moon, YS; Park, JB; Park, KK; Park, NG; Park, YY; Sin, DI; Yeo, JH, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ren, Y | 1 |
| Lin, Y | 1 |
| Chen, J | 1 |
| Jin, Y | 1 |
| Guo, W | 1 |
| Zhang, X | 1 |
| Lin, L | 1 |
| Wang, H | 1 |
| He, E | 1 |
| Wang, G | 1 |
| Zhao, Q | 1 |
| Yu, S | 1 |
| Fourman, MS | 1 |
| Mahjoub, A | 1 |
| Mandell, JB | 1 |
| Crasto, JA | 1 |
| Greco, NG | 1 |
| Weiss, KR | 1 |
| Cho, HJ | 1 |
| Lee, TS | 1 |
| Park, JB | 1 |
| Park, KK | 1 |
| Choe, JY | 1 |
| Sin, DI | 1 |
| Park, YY | 1 |
| Moon, YS | 1 |
| Lee, KG | 1 |
| Yeo, JH | 1 |
| Han, SM | 1 |
| Cho, YS | 1 |
| Choi, MR | 1 |
| Park, NG | 1 |
| Lee, YS | 1 |
| Chang, YC | 1 |
4 other studies available for disulfiram and Osteosarcoma
| Article | Year |
|---|---|
Disulfiram Chelated with Copper Promotes Apoptosis in Osteosarcoma via ROS/Mitochondria Pathway.
Topics: Animals; Apoptosis; Bone Neoplasms; Cell Line, Tumor; Chelating Agents; Copper; Disulfiram; Humans; | 2021 |
The disulfiram/copper complex induces apoptosis and inhibits tumour growth in human osteosarcoma by activating the ROS/JNK signalling pathway.
Topics: Animals; Antineoplastic Agents; Apoptosis; Autophagy; Bone Neoplasms; Cell Line, Tumor; Cell Prolife | 2021 |
Lung cells support osteosarcoma cell migration and survival.
Topics: Aldehyde Dehydrogenase 1 Family; Alkaline Phosphatase; Animals; Biomarkers, Tumor; Cell Line, Tumor; | 2017 |
Disulfiram suppresses invasive ability of osteosarcoma cells via the inhibition of MMP-2 and MMP-9 expression.
Topics: Antineoplastic Agents; Base Sequence; Cell Line, Tumor; Disulfiram; DNA Primers; Enzyme Inhibitors; | 2007 |