Page last updated: 2024-10-26

disulfiram and Liver Cirrhosis

disulfiram has been researched along with Liver Cirrhosis in 8 studies

Liver Cirrhosis: Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.

Research Excerpts

ExcerptRelevanceReference
"A 43 year old man with HIV and HCV infection and liver cirrhosis developed fatal lactic acidosis within five days from starting nifedipine for arterial hypertension."7.75Fatal lactic acidosis precipitated by nifedipine in a patient treated with disulfiram and antiretrovirals. ( Mian, P; Moling, O; Pagani, L; Pristerà, R; Rimenti, G; Spoladore, G; Vedovelli, C, 2009)
"A 43 year old man with HIV and HCV infection and liver cirrhosis developed fatal lactic acidosis within five days from starting nifedipine for arterial hypertension."3.75Fatal lactic acidosis precipitated by nifedipine in a patient treated with disulfiram and antiretrovirals. ( Mian, P; Moling, O; Pagani, L; Pristerà, R; Rimenti, G; Spoladore, G; Vedovelli, C, 2009)
" The serum tetrazole concentration was determined following intravenous administration of cefoperazone (CPZ) 1 g, latamoxef (LMOX) 1 g, or cefmetazole (CMZ) 2 g to patients suffering infections without liver dysfunction, and of CPZ 1 g to patients with liver cirrhosis."3.67[Free methyltetrazolethiol concentrations in men subjected to intravenous administration of cephems with methyltetrazolethiol]. ( Hirai, Y; Imamura, K; Kudo, H; Kumasaka, Y; Makino, I; Miyazawa, T; Nakahata, H; Nakamura, T; Takebe, K, 1987)
"But the actual effects of DSF on liver fibrosis and liver function remain unknown."1.72Disulfiram inhibits liver fibrosis in rats by suppressing hepatic stellate cell activation and viability. ( Li, D; Li, J; Ma, X; Nie, HZ; Wang, X; Wang, YH; Wu, Z; Yang, XM; Zhou, Y; Zhu, L, 2022)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19905 (62.50)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's1 (12.50)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Yang, XM1
Wu, Z1
Wang, X1
Zhou, Y1
Zhu, L1
Li, D1
Nie, HZ1
Wang, YH1
Li, J1
Ma, X1
Moling, O1
Rimenti, G1
Pristerà, R1
Vedovelli, C1
Pagani, L1
Spoladore, G1
Mian, P1
Lutz, W1
Szeszko, A1
Kendrey, G1
Sziza, M1
Nakahata, H1
Hirai, Y1
Kumasaka, Y1
Miyazawa, T1
Nakamura, T1
Imamura, K1
Makino, I1
Takebe, K1
Kudo, H1
Hepner, GW1
Vesell, ES1
Jay, M1

Other Studies

8 other studies available for disulfiram and Liver Cirrhosis

ArticleYear
Disulfiram inhibits liver fibrosis in rats by suppressing hepatic stellate cell activation and viability.
    BMC pharmacology & toxicology, 2022, 07-22, Volume: 23, Issue:1

    Topics: Animals; Bile Ducts; Cell Proliferation; Disulfiram; Hepatic Stellate Cells; Humans; Liver; Liver Ci

2022
KASL clinical practice guidelines: management of alcoholic liver disease.
    Clinical and molecular hepatology, 2013, Volume: 19, Issue:3

    Topics: Alcohol Abstinence; Alcohol Drinking; Alcohol-Related Disorders; Baclofen; Disulfiram; Fatty Liver,

2013
Fatal lactic acidosis precipitated by nifedipine in a patient treated with disulfiram and antiretrovirals.
    Drug metabolism letters, 2009, Volume: 3, Issue:3

    Topics: Acidosis, Lactic; Adult; Alcohol Deterrents; Alcoholism; Anti-Retroviral Agents; Antihypertensive Ag

2009
[Diagnostic value of the antabuse test in liver cirrhosis].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1984, Nov-19, Volume: 39, Issue:47

    Topics: Adult; Aged; Disulfiram; Humans; Liver Cirrhosis; Liver Function Tests; Middle Aged

1984
[Morphological studies on the hepatotoxic effect of Thiuram (tetramethylthiuram disulphide) in white rats].
    Morphologiai es igazsagugyi orvosi szemle, 1975, Volume: 15, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Disulfiram; Liver; Liver Cirrhosis; Rats

1975
[Free methyltetrazolethiol concentrations in men subjected to intravenous administration of cephems with methyltetrazolethiol].
    The Japanese journal of antibiotics, 1987, Volume: 40, Issue:7

    Topics: Aldehyde Oxidoreductases; Azoles; Biotransformation; Cefmetazole; Cefoperazone; Cephalosporins; Ceph

1987
Assessment of aminopyrine metabolism in man by breath analysis after oral administration of 14C-aminopyrine. Effects of phenobarbital, disulfiram and portal cirrhosis.
    The New England journal of medicine, 1974, Dec-26, Volume: 291, Issue:26

    Topics: Administration, Oral; Adult; Aged; Alcoholism; Aminopyrine; Breath Tests; Carbon Dioxide; Carbon Rad

1974
[Alcoholism on Réunion].
    Annales medico-psychologiques, 1965, Volume: 123, Issue:1

    Topics: Adolescent; Adult; Alcoholism; Apomorphine; Disulfiram; Fatty Liver; Female; Gastritis; Humans; Indi

1965