Page last updated: 2024-10-26

disulfiram and Leukemia, Myeloid, Acute

disulfiram has been researched along with Leukemia, Myeloid, Acute in 5 studies

Leukemia, Myeloid, Acute: Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES.

Research Excerpts

ExcerptRelevanceReference
"Disulfiram (DSF) is an aldehyde dehydrogenase inhibitor currently used for the treatment of alcoholism."1.38Disulfiram, an old drug with new potential therapeutic uses for human hematological malignancies. ( Adamo, L; Amato, G; Anastasi, G; Buccheri, S; Cavalli, M; Chiarenza, A; Conticello, C; De Maria, R; Di Raimondo, F; Giuffrida, R; Giustolisi, R; Gulisano, M; Lombardo, L; Martinetti, D; Parrinello, N, 2012)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's4 (80.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hassani, S1
Ghaffari, P1
Chahardouli, B1
Alimoghaddam, K1
Ghavamzadeh, A1
Alizadeh, S1
Ghaffari, SH1
Dong, H1
Li, R1
Zheng, Z1
He, H1
Zhou, Y1
Deng, M1
Li, Y1
Wang, X1
Zhou, S2
Xu, B2
Shi, P1
Fombon, IS1
Zhang, Y1
Huang, F1
Wang, W1
Conticello, C1
Martinetti, D1
Adamo, L1
Buccheri, S1
Giuffrida, R1
Parrinello, N1
Lombardo, L1
Anastasi, G1
Amato, G1
Cavalli, M1
Chiarenza, A1
De Maria, R1
Giustolisi, R1
Gulisano, M1
Di Raimondo, F1
de Groot, CJ1
Martens, AC1
Hagenbeek, A1

Other Studies

5 other studies available for disulfiram and Leukemia, Myeloid, Acute

ArticleYear
Disulfiram/copper causes ROS levels alteration, cell cycle inhibition, and apoptosis in acute myeloid leukaemia cell lines with modulation in the expression of related genes.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 99

    Topics: Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Copper; Disulfiram; G1 Phase; Gene Expression R

2018
[The lethal effect of disulfiram/cooper complex in NOD/SCID mouse model with acute myeloid leukemia].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2014, Volume: 35, Issue:9

    Topics: Animals; Copper; Disulfiram; Humans; Leukemia, Myeloid, Acute; Mice; Mice, Inbred NOD; Mice, SCID

2014
Disulfiram/copper complex activated JNK/c-jun pathway and sensitized cytotoxicity of doxorubicin in doxorubicin resistant leukemia HL60 cells.
    Blood cells, molecules & diseases, 2011, Dec-15, Volume: 47, Issue:4

    Topics: Apoptosis; Cell Line, Tumor; Copper; Disulfiram; Doxorubicin; Drug Resistance, Neoplasm; Drug Synerg

2011
Disulfiram, an old drug with new potential therapeutic uses for human hematological malignancies.
    International journal of cancer, 2012, Nov-01, Volume: 131, Issue:9

    Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; Caspases; Cell Line, Tumor; Copper; Disulfiram; En

2012
Aldehyde dehydrogenase involvement in a variant of the brown Norway rat acute myelocytic leukaemia (BNML) that acquired cyclophosphamide resistance in vivo.
    European journal of cancer (Oxford, England : 1990), 1994, Volume: 30A, Issue:14

    Topics: Aldehyde Dehydrogenase; Animals; Antineoplastic Agents; Cyclophosphamide; Disulfiram; Drug Resistanc

1994