disulfiram has been researched along with Invasiveness, Neoplasm in 8 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this study, we reported the effects of disulfiram, a clinically used anti-alcoholism drug, on tumor invasion suppression, as well as its effects on the activity of MMP-2 and MMP-9 in human osteosarcoma cells (U2OS)." | 7.74 | Disulfiram suppresses invasive ability of osteosarcoma cells via the inhibition of MMP-2 and MMP-9 expression. ( Chang, YC; Cho, HJ; Cho, YS; Choe, JY; Choi, MR; Han, SM; Lee, KG; Lee, TS; Lee, YS; Moon, YS; Park, JB; Park, KK; Park, NG; Park, YY; Sin, DI; Yeo, JH, 2007) |
| "Disulfiram (DSF) has copper (Cu)-dependent anticancer properties in vitro and in vivo." | 5.48 | Disulfiram combined with copper inhibits metastasis and epithelial-mesenchymal transition in hepatocellular carcinoma through the NF-κB and TGF-β pathways. ( Li, TY; Li, Y; Liu, S; Wang, LH; Wang, YT; Wu, CF; Yang, JY; Yuan, XZ; Zhang, HT; Zhou, WL, 2018) |
| " In this study, we reported the effects of disulfiram, a clinically used anti-alcoholism drug, on tumor invasion suppression, as well as its effects on the activity of MMP-2 and MMP-9 in human osteosarcoma cells (U2OS)." | 3.74 | Disulfiram suppresses invasive ability of osteosarcoma cells via the inhibition of MMP-2 and MMP-9 expression. ( Chang, YC; Cho, HJ; Cho, YS; Choe, JY; Choi, MR; Han, SM; Lee, KG; Lee, TS; Lee, YS; Moon, YS; Park, JB; Park, KK; Park, NG; Park, YY; Sin, DI; Yeo, JH, 2007) |
| "Disulfiram (DSF) has copper (Cu)-dependent anticancer properties in vitro and in vivo." | 1.48 | Disulfiram combined with copper inhibits metastasis and epithelial-mesenchymal transition in hepatocellular carcinoma through the NF-κB and TGF-β pathways. ( Li, TY; Li, Y; Liu, S; Wang, LH; Wang, YT; Wu, CF; Yang, JY; Yuan, XZ; Zhang, HT; Zhou, WL, 2018) |
| "Disulfiram (DSF) is an approved drug for the treatment of alcohol dependence, but has also been shown to kill TNBC cells in a copper (Cu)-dependent manner." | 1.46 | Disulfiram induces anoikis and suppresses lung colonization in triple-negative breast cancer via calpain activation. ( An, H; Cho, TM; Cho, Y; Kim, JY; Kim, YJ; Lee, N; Oh, E; Seo, JH; Sung, D, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 7 (87.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hwang, S | 1 |
| Shin, DM | 1 |
| Hong, JH | 1 |
| Li, Y | 2 |
| Wang, LH | 2 |
| Zhang, HT | 1 |
| Wang, YT | 2 |
| Liu, S | 1 |
| Zhou, WL | 1 |
| Yuan, XZ | 1 |
| Li, TY | 1 |
| Wu, CF | 2 |
| Yang, JY | 2 |
| Mettang, M | 1 |
| Meyer-Pannwitt, V | 1 |
| Karpel-Massler, G | 2 |
| Zhou, S | 2 |
| Carragher, NO | 2 |
| Föhr, KJ | 1 |
| Baumann, B | 2 |
| Nonnenmacher, L | 2 |
| Enzenmüller, S | 1 |
| Dahlhaus, M | 1 |
| Siegelin, MD | 1 |
| Stroh, S | 1 |
| Mertens, D | 1 |
| Fischer-Posovszky, P | 1 |
| Schneider, EM | 1 |
| Halatsch, ME | 2 |
| Debatin, KM | 2 |
| Westhoff, MA | 2 |
| Jennewein, C | 1 |
| Schneider, M | 1 |
| Krause, A | 1 |
| Simmet, T | 1 |
| Bachem, MG | 1 |
| Wirtz, CR | 1 |
| Fu, SY | 1 |
| Wang, FY | 1 |
| Wang, NN | 1 |
| Cao, Q | 1 |
| Kim, JY | 1 |
| Lee, N | 1 |
| Kim, YJ | 1 |
| Cho, Y | 1 |
| An, H | 1 |
| Oh, E | 1 |
| Cho, TM | 1 |
| Sung, D | 1 |
| Seo, JH | 1 |
| Ketola, K | 1 |
| Kallioniemi, O | 1 |
| Iljin, K | 1 |
| Cho, HJ | 1 |
| Lee, TS | 1 |
| Park, JB | 1 |
| Park, KK | 1 |
| Choe, JY | 1 |
| Sin, DI | 1 |
| Park, YY | 1 |
| Moon, YS | 1 |
| Lee, KG | 1 |
| Yeo, JH | 1 |
| Han, SM | 1 |
| Cho, YS | 1 |
| Choi, MR | 1 |
| Park, NG | 1 |
| Lee, YS | 1 |
| Chang, YC | 1 |
8 other studies available for disulfiram and Invasiveness, Neoplasm
| Article | Year |
|---|---|
Drug Repurposing as an Antitumor Agent: Disulfiram-Mediated Carbonic Anhydrase 12 and Anion Exchanger 2 Modulation to Inhibit Cancer Cell Migration.
Topics: Antineoplastic Agents; Carbonic Anhydrases; Cell Line, Tumor; Cell Membrane; Cell Movement; Chloride | 2019 |
Disulfiram combined with copper inhibits metastasis and epithelial-mesenchymal transition in hepatocellular carcinoma through the NF-κB and TGF-β pathways.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Copper; Disulfiram; Down-Regula | 2018 |
Blocking distinct interactions between Glioblastoma cells and their tissue microenvironment: A novel multi-targeted therapeutic approach.
Topics: Acetaldehyde Dehydrogenase Inhibitors; Animals; Anti-Ulcer Agents; Apoptosis; Brain Neoplasms; Carbe | 2018 |
Inhibition of NF-κB signaling ablates the invasive phenotype of glioblastoma.
Topics: Animals; Cell Line, Tumor; Cell Movement; Disulfiram; Enzyme Inhibitors; Fibronectins; Gene Expressi | 2013 |
Copper improves the anti-angiogenic activity of disulfiram through the EGFR/Src/VEGF pathway in gliomas.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; | 2015 |
Disulfiram induces anoikis and suppresses lung colonization in triple-negative breast cancer via calpain activation.
Topics: Animals; Anoikis; Antineoplastic Agents; Calpain; Cell Line, Tumor; Cell Movement; Cell Proliferatio | 2017 |
Chemical biology drug sensitivity screen identifies sunitinib as synergistic agent with disulfiram in prostate cancer cells.
Topics: Apoptosis; Cadherins; Cell Line, Tumor; Cell Movement; Cell Survival; Disulfiram; Drug Screening Ass | 2012 |
Disulfiram suppresses invasive ability of osteosarcoma cells via the inhibition of MMP-2 and MMP-9 expression.
Topics: Antineoplastic Agents; Base Sequence; Cell Line, Tumor; Disulfiram; DNA Primers; Enzyme Inhibitors; | 2007 |