Page last updated: 2024-10-26

disulfiram and Idiopathic Parkinson Disease

disulfiram has been researched along with Idiopathic Parkinson Disease in 8 studies

Research Excerpts

ExcerptRelevanceReference
" A toxic product of lipid peroxidation, (±)-4-hydroxy-2E-nonenal (HNE) leads to membrane disruption and formation of HNE-protein adducts and such adducts have been detected in PD brain tissues."1.38Modulation of aldehyde dehydrogenase activity affects (±)-4-hydroxy-2E-nonenal (HNE) toxicity and HNE-protein adduct levels in PC12 cells. ( Kong, D; Kotraiah, V, 2012)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19906 (75.00)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kong, D1
Kotraiah, V1
Charles, V1
Boulvin, S1
Haven, F1
Gille, M1
Arushanian, EB1
Birket-Smith, E1
Andersen, JV1
Presthus, J1
Bianchine, JR1
Sunyapridakul, L1
Duvoisin, RC1
Marsden, CD1
Braham, J1

Reviews

2 reviews available for disulfiram and Idiopathic Parkinson Disease

ArticleYear
[Other trials with drug therapy in parkinsonism].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1973, Oct-10, Volume: 93, Issue:28

    Topics: 5-Hydroxytryptophan; Amitriptyline; Animals; Dihydroxyphenylalanine; Disulfiram; Drug Evaluation; Dr

1973
Individualization of levodopa therapy.
    The Medical clinics of North America, 1974, Volume: 58, Issue:5

    Topics: Amantadine; Amphetamine; Anesthetics; Animals; Antihypertensive Agents; Apomorphine; Arrhythmias, Ca

1974

Other Studies

6 other studies available for disulfiram and Idiopathic Parkinson Disease

ArticleYear
Modulation of aldehyde dehydrogenase activity affects (±)-4-hydroxy-2E-nonenal (HNE) toxicity and HNE-protein adduct levels in PC12 cells.
    Journal of molecular neuroscience : MN, 2012, Volume: 47, Issue:3

    Topics: Aldehyde Dehydrogenase 1 Family; Aldehydes; Animals; Cell Death; Disulfiram; DNA Adducts; Lipid Pero

2012
[Wernicke's encephalopathy associated with chronic disulfiram intoxication].
    Revue neurologique, 2006, Volume: 162, Issue:12

    Topics: Adult; Disulfiram; Humans; Magnetic Resonance Imaging; Male; Parkinson Disease; Wernicke Encephalopa

2006
[The phenomenon of experimental motor retardation as one of the manifestations of the Parkinsonian syndrome].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1975, Volume: 75, Issue:4

    Topics: Amphetamine; Animals; Catecholamines; Cats; Caudate Nucleus; Chlorpromazine; Dihydroergotoxine; Dise

1975
Treatment of side-effects of levodopa.
    Lancet (London, England), 1973, Feb-24, Volume: 1, Issue:7800

    Topics: Dihydroxyphenylalanine; Disulfiram; Humans; Hyperkinesis; Hypertension; Parkinson Disease

1973
Reversal of reserpine-induced bradykinesia by alpha-methyldopa--new light on its modus operandi.
    Brain research, 1974, May-10, Volume: 71, Issue:1

    Topics: Animals; Carbidopa; Chlorpromazine; Dihydroxyphenylalanine; Disease Models, Animal; Disulfiram; Dose

1974
Adjuvants to L-dopa for Parkinsonism.
    British medical journal, 1970, May-30, Volume: 2, Issue:5708

    Topics: Animals; Cats; Dihydroxyphenylalanine; Disulfiram; Drug Synergism; Humans; Isoniazid; Parkinson Dise

1970