Page last updated: 2024-10-26

disulfiram and Huntington Disease

disulfiram has been researched along with Huntington Disease in 2 studies

Huntington Disease: A familial disorder inherited as an autosomal dominant trait and characterized by the onset of progressive CHOREA and DEMENTIA in the fourth or fifth decade of life. Common initial manifestations include paranoia; poor impulse control; DEPRESSION; HALLUCINATIONS; and DELUSIONS. Eventually intellectual impairment; loss of fine motor control; ATHETOSIS; and diffuse chorea involving axial and limb musculature develops, leading to a vegetative state within 10-15 years of disease onset. The juvenile variant has a more fulminant course including SEIZURES; ATAXIA; dementia; and chorea. (From Adams et al., Principles of Neurology, 6th ed, pp1060-4)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19902 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lamprecht, F1
Mattsson, B1
Bertilsson, L1

Reviews

1 review available for disulfiram and Huntington Disease

ArticleYear
Epilepsy and schizophrenia: a neurochemical bridge.
    Journal of neural transmission, 1977, Volume: 40, Issue:2

    Topics: Amphetamine; Anticonvulsants; Brain; Butyrophenones; Disulfiram; Dopamine; Dopamine beta-Hydroxylase

1977

Other Studies

1 other study available for disulfiram and Huntington Disease

ArticleYear
Treatment with disulfiram in huntington's chorea.
    Acta psychiatrica Scandinavica. Supplementum, 1974, Volume: 255

    Topics: Adult; Aged; Disulfiram; Dopamine beta-Hydroxylase; Female; Homovanillic Acid; Humans; Huntington Di

1974