disulfiram has been researched along with Hemolysis in 4 studies
Hemolysis: The destruction of ERYTHROCYTES by many different causal agents such as antibodies, bacteria, chemicals, temperature, and changes in tonicity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Disulfiram was found to readily hemolyze erythrocytes at low concentrations as well as to crosslink the proteins in the erythrocyte membrane." | 5.28 | Disulfiram may mediate erythrocyte hemolysis induced by diethyldithiocarbamate and 1,4-naphthoquinone-2-sulfonate. ( Lauriault, VV; O'Brien, PJ, 1991) |
| " It is not possible to generalize with regard to the effects of modulation of tissue levels of DT-diaphorase on naphthoquinone toxicity in vivo, since this may change not only the severity of the toxic effects, but also the target organ specificity." | 1.33 | Effect of inducers of DT-diaphorase on the haemolytic activity and nephrotoxicity of 2-amino-1,4-naphthoquinone in rats. ( Munday, CM; Munday, R; Smith, BL, 2005) |
| "Disulfiram was found to readily hemolyze erythrocytes at low concentrations as well as to crosslink the proteins in the erythrocyte membrane." | 1.28 | Disulfiram may mediate erythrocyte hemolysis induced by diethyldithiocarbamate and 1,4-naphthoquinone-2-sulfonate. ( Lauriault, VV; O'Brien, PJ, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mohammad, IS | 1 |
| Teng, C | 1 |
| Chaurasiya, B | 1 |
| Yin, L | 1 |
| Wu, C | 1 |
| He, W | 1 |
| Munday, R | 1 |
| Smith, BL | 1 |
| Munday, CM | 1 |
| Lauriault, VV | 1 |
| O'Brien, PJ | 1 |
| Johansson, B | 1 |
4 other studies available for disulfiram and Hemolysis
| Article | Year |
|---|---|
Drug-delivering-drug approach-based codelivery of paclitaxel and disulfiram for treating multidrug-resistant cancer.
Topics: A549 Cells; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biologic | 2019 |
Effect of inducers of DT-diaphorase on the haemolytic activity and nephrotoxicity of 2-amino-1,4-naphthoquinone in rats.
Topics: Anemia, Hemolytic; Animals; Biotransformation; Butylated Hydroxyanisole; Butylated Hydroxytoluene; D | 2005 |
Disulfiram may mediate erythrocyte hemolysis induced by diethyldithiocarbamate and 1,4-naphthoquinone-2-sulfonate.
Topics: Animals; Cross-Linking Reagents; Disulfiram; Ditiocarb; Erythrocyte Membrane; Glutathione; Hemolysis | 1991 |
Distribution of disulfiram and its chief metabolites over erythrocyte cell membranes and inactivation of erythrocyte aldehyde dehydrogenase activity.
Topics: Acetaldehyde; Aldehyde Dehydrogenase; Disulfiram; Erythrocyte Membrane; Erythrocytes; Hemolysis; Hum | 1990 |